Citations (46)
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Agnese Anna Abate, Francesca Pentimalli, Luca Esposito & Antonio Giordano. (2013) ATP-noncompetitive CDK inhibitors for cancer therapy: an overview. Expert Opinion on Investigational Drugs 22:7, pages 895-906.
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Hervé Galons, Nassima Oumata, Olfa Gloulou & Laurent Meijer. (2013) Cyclin-dependent kinase inhibitors closer to market launch?. Expert Opinion on Therapeutic Patents 23:8, pages 945-963.
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Ahmed Soffar, Katja Storch, Eiman Aleem & Nils Cordes. (2013) CDK2 knockdown enhances head and neck cancer cell radiosensitivity. International Journal of Radiation Biology 89:7, pages 523-531.
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Seon Hee Shin & Kwang Sik Kim. (2012) Treatment of bacterial meningitis: an update. Expert Opinion on Pharmacotherapy 13:15, pages 2189-2206.
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Józefa Węsierska-Gądek & Matthias P Kramer. (2011) The impact of multi-targeted cyclin-dependent kinase inhibition in breast cancer cells: clinical implications. Expert Opinion on Investigational Drugs 20:12, pages 1611-1628.
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Articles from other publishers (41)
Ghanshyam Tiwari, Ashish Khanna, Vinay Kumar Mishra & Ram Sagar. (2023) Recent developments on microwave-assisted organic synthesis of nitrogen- and oxygen-containing preferred heterocyclic scaffolds. RSC Advances 13:47, pages 32858-32892.
Crossref
Crossref
Manzoor Ahmad Mir & Burhan Ul Haq. 2023. Therapeutic potential of Cell Cycle Kinases in Breast Cancer. Therapeutic potential of Cell Cycle Kinases in Breast Cancer
195
210
.
Manzoor Ahmad Mir & Burhan Ul Haq. 2023. Therapeutic potential of Cell Cycle Kinases in Breast Cancer. Therapeutic potential of Cell Cycle Kinases in Breast Cancer
233
252
.
Vivek Asati, Arjun Anant, Preeti Patel, Kamalpreet Kaur & G.D. Gupta. (2021) Pyrazolopyrimidines as anticancer agents: A review on structural and target-based approaches. European Journal of Medicinal Chemistry 225, pages 113781.
Crossref
Crossref
Nadia Hanafy Metwally, Mona Said Mohamed & Emad Abdullah Deeb. (2021) Synthesis, anticancer evaluation, CDK2 inhibition, and apoptotic activity assessment with molecular docking modeling of new class of pyrazolo[1,5-a]pyrimidines. Research on Chemical Intermediates 47:12, pages 5027-5060.
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Crossref
Srinivasa Rao Dasari, Subbaiah Tondepu, Lakshmana Rao Vadali & Nareshvarma Seelam. (2019)
Retracted
: Design, Synthesis and Molecular Modeling of Nonsteroidal Anti‐inflammatory Drugs Tagged Substituted 1,2,3‐Triazole Derivatives and Evaluation of Their Biological Activities
. Journal of Heterocyclic Chemistry 56:4, pages 1318-1329.
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Natalie A. Jabbour-Leung, Xian Chen, Tuyen Bui, Yufeng Jiang, Dong Yang, Smruthi Vijayaraghavan, Mark J. McArthur, Kelly K. Hunt & Khandan Keyomarsi. (2016) Sequential Combination Therapy of CDK Inhibition and Doxorubicin Is Synthetically Lethal in p53-Mutant Triple-Negative Breast Cancer. Molecular Cancer Therapeutics 15:4, pages 593-607.
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Oriana Tabarrini, Jenny Desantis & Serena Massari. (2016) Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV. Future Medicinal Chemistry 8:4, pages 421-442.
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Eva Řezníčková, Sabine Weitensteiner, Libor Havlíček, Radek Jorda, Tomáš Gucký, Karel Berka, Václav Bazgier, Stefan Zahler, Vladimír Kryštof & Miroslav Strnad. (2015)
Characterization of a Pyrazolo[4,3-
d
]pyrimidine Inhibitor of Cyclin-Dependent Kinases 2 and 5 and Aurora A With Pro-Apoptotic and Anti-Angiogenic Activity
In Vitro
. Chemical Biology & Drug Design 86:6, pages 1528-1540.
Crossref
Crossref
Carmen Avendaño & J. Carlos Menéndez. 2015. Medicinal Chemistry of Anticancer Drugs. Medicinal Chemistry of Anticancer Drugs
391
491
.
C Norez, C Vandebrouck, J Bertrand, S Noel, E Durieu, N Oumata, H Galons, F Antigny, A Chatelier, P Bois, L Meijer & F Becq. (2014) Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism. British Journal of Pharmacology 171:21, pages 4831-4849.
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M. Jarry, C. Lecointre, C. Malleval, L. Desrues, M.-T. Schouft, V. Lejoncour, F. Liger, G. Lyvinec, B. Joseph, N. Loaec, L. Meijer, J. Honnorat, P. Gandolfo & H. Castel. (2014) Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis. Neuro-Oncology 16:11, pages 1484-1498.
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Cécile Voisset, Néstor García-Rodríguez, April Birkmire, Marc Blondel & Ralf Erik Wellinger. (2014) Using yeast to model calcium-related diseases: Example of the Hailey–Hailey disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:10, pages 2315-2321.
Crossref
Crossref
Gaëlle Mariaule & Philippe Belmont. (2014) Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey. Molecules 19:9, pages 14366-14382.
Crossref
Crossref
Oussama Dehbi, Abdellatif Tikad, Stéphane Bourg, Pascal Bonnet, Olivier Lozach, Laurent Meijer, Mina Aadil, Mohammed Akssira, Gérald Guillaumet & Sylvain Routier. (2014) Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted Pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors. European Journal of Medicinal Chemistry 80, pages 352-363.
Crossref
Crossref
CHEOL PARK, NA YOUNG JEONG, GI-YOUNG KIM, MIN HO HAN, ILL-MIN CHUNG, WUN-JAE KIM, YOUNG HYUN YOO & YUNG HYUN CHOI. (2014) Momilactone B induces apoptosis and G1 arrest of the cell cycle in human monocytic leukemia U937 cells through downregulation of pRB phosphorylation and induction of the cyclin-dependent kinase inhibitor p21Waf1/Cip1. Oncology Reports 31:4, pages 1653-1660.
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Irene Guendel, Sergey Iordanskiy, Rachel Van Duyne, Kylene Kehn-Hall, Mohammed Saifuddin, Ravi Das, Elizabeth Jaworski, Gavin C. Sampey, Svetlana Senina, Leonard Shultz, Aarthi Narayanan, Hao Chen, Benjamin Lepene, Chen Zeng & Fatah Kashanchi. (2014) Novel Neuroprotective GSK-3β Inhibitor Restricts Tat-Mediated HIV-1 Replication. Journal of Virology 88:2, pages 1189-1208.
Crossref
Crossref
Benoit CarbainDavid J. PatersonElizabeth AnscombeAllyson J. CampbellCeline CanoAude EchalierJane A. EndicottBernard T. GoldingKaren HaggertyIan R. HardcastlePhilip J. JewsburyDavid R. NewellMartin E. M. NobleCeline RocheLan Z. WangRoger J. Griffin. (2013)
8-Substituted
O
6
-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode
. Journal of Medicinal Chemistry 57:1, pages 56-70.
Crossref
Crossref
Céline Bruyère & Laurent Meijer. (2013) Targeting cyclin-dependent kinases in anti-neoplastic therapy. Current Opinion in Cell Biology 25:6, pages 772-779.
Crossref
Crossref
Reine Nehmé, Hala Nehmé, Grégory Roux, Emilie Destandau, Bérengère Claude & Philippe Morin. (2013) Capillary electrophoresis as a novel technique for screening natural flavonoids as kinase inhibitors. Journal of Chromatography A 1318, pages 257-264.
Crossref
Crossref
Mohamed Elagawany, Mohamed A. Ibrahim, Hany Emary Ali Ahmed, A.Sh. El-Etrawy, Adel Ghiaty, Zakaria K. Abdel-Samii, Said A. El-Feky & Jürgen Bajorath. (2013) Design, synthesis, and molecular modelling of pyridazinone and phthalazinone derivatives as protein kinases inhibitors. Bioorganic & Medicinal Chemistry Letters 23:7, pages 2007-2013.
Crossref
Crossref
Gabriele Montanaro, Massimo Bertinaria, Barbara Rolando, Roberta Fruttero, Christopher D. Lucas, David A. Dorward, Adriano G. Rossi, Ian L. Megson & Alberto Gasco. (2013) Novel R-roscovitine NO-donor hybrid compounds as potential pro-resolution of inflammation agents. Bioorganic & Medicinal Chemistry 21:7, pages 2107-2116.
Crossref
Crossref
Sergei NekhaiNamita Kumari & Subhash Dhawan. (2013) Role of cellular iron and oxygen in the regulation of HIV-1 infection. Future Virology 8:3, pages 301-311.
Crossref
Crossref
Takayuki Iwata, Katsunori Tanaka, Tsuyoshi Tahara, Satoshi Nozaki, Hirotaka Onoe, Yasuyoshi Watanabe & Koichi Fukase. (2013) A conformationally fixed analog of the peptide mimic Grb2–SH2 domain: synthesis and evaluation against the A431 cancer cell. Molecular BioSystems 9:5, pages 1019.
Crossref
Crossref
Denitra Breuer, Alexander Kotelkin, Tatiana Ammosova, Namita Kumari, Andrey Ivanov, Andrey V Ilatovskiy, Monique Beullens, Philip R Roane, Mathieu Bollen, Michael G Petukhov, Fatah Kashanchi & Sergei Nekhai. (2012) CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90. Retrovirology 9:1.
Crossref
Crossref
Cécile Apel, Vincent Dumontet, Olivier Lozach, Laurent Meijer, Françoise Guéritte & Marc Litaudon. (2012) Phenanthrene derivatives from Appendicula reflexa as new CDK1/cyclin B inhibitors. Phytochemistry Letters 5:4, pages 814-818.
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Crossref
Aarthi Narayanan, Gavin Sampey, Rachel Van Duyne, Irene Guendel, Kylene Kehn-Hall, Jessica Roman, Robert Currer, Hervé Galons, Nassima Oumata, Benoît Joseph, Laurent Meijer, Massimo Caputi, Sergei Nekhai & Fatah Kashanchi. (2012) Use of ATP analogs to inhibit HIV-1 transcription. Virology 432:1, pages 219-231.
Crossref
Crossref
Joannah N'gompaza-Diarra, Karima Bettayeb, Nohad Gresh, Laurent Meijer & Nassima Oumata. (2012) Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors. European Journal of Medicinal Chemistry 56, pages 210-216.
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Crossref
Abul Arif. (2012) Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5. Biochemical Pharmacology 84:8, pages 985-993.
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Crossref
Katsunori Tanaka, Sanae Shirotsuki, Takayuki Iwata, Chika Kageyama, Tsuyoshi Tahara, Satoshi Nozaki, Eric R. O. Siwu, Satoru Tamura, Shunsuke Douke, Nobutoshi Murakami, Hirotaka Onoe, Yasuyoshi Watanabe & Koichi Fukase. (2012) Template-Assisted and Self-Activating Clicked Peptide as a Synthetic Mimic of the SH2 Domain. ACS Chemical Biology 7:4, pages 637-645.
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Crossref
Angela Nanos-Webb, Natalie A. Jabbour, Asha S. Multani, Hannah Wingate, Nassima Oumata, Hervé Galons, Benoît Joseph, Laurent Meijer, Kelly K. Hunt & Khandan Keyomarsi. (2011) Targeting low molecular weight cyclin E (LMW-E) in breast cancer. Breast Cancer Research and Treatment 132:2, pages 575-588.
Crossref
Crossref
Józefa Węsierska-GądekMatthias P Kramer. (2012) The impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules. Future Medicinal Chemistry 4:4, pages 395-424.
Crossref
Crossref
Pamela Kassis, Joanna Brzeszcz, Valérie Bénéteau, Olivier Lozach, Laurent Meijer, Rémi Le Guével, Christiane Guillouzo, Krzysztof Lewiński, Stéphane Bourg, Lionel Colliandre, Sylvain Routier & Jean-Yves Mérour. (2011) Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents. European Journal of Medicinal Chemistry 46:11, pages 5416-5434.
Crossref
Crossref
Caroline Corbel, Qian Wang, Hadjira Bousserouel, Amel Hamdi, Bing Zhang, Olivier Lozach, Yoan Ferandin, Vincent B. C. Tan, Françoise Guéritte, Pierre Colas, Cyril Couturier & Stéphane Bach. (2011) First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors. Biotechnology Journal 6:7, pages 860-870.
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Crossref
Kylene Kehn-Hall, Irene Guendel, Lawrence Carpio, Leandros Skaltsounis, Laurent Meijer, Lena Al-Harthi, Joseph P. Steiner, Avindra Nath, Olaf Kutsch & Fatah Kashanchi. (2011) Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology 415:1, pages 56-68.
Crossref
Crossref
Tony J. Vanden Bush & Gail A. Bishop. (2011) CDK-Mediated Regulation of Cell Functions via c-Jun Phosphorylation and AP-1 Activation. PLoS ONE 6:4, pages e19468.
Crossref
Crossref
Józefa Węsierska-Gądek, David Gritsch, Nora Zulehner, Oxana Komina & Margarita Maurer. (2011) Interference with ER-α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER-positive breast cancer cells. Journal of Cellular Biochemistry 112:4, pages 1103-1117.
Crossref
Crossref
Laura Delgado-Soler, Javier Ariñez-Soriano, José M. Granadino-Roldán & Jaime Rubio-Martinez. (2010) Predicting binding energies of CDK6 inhibitors in the hit-to-lead process. Theoretical Chemistry Accounts 128:4-6, pages 807-823.
Crossref
Crossref
Józefa Węsierska-Gądek, David Gritsch, Nora Zulehner, Oxana Komina & Margarita Maurer. (2011) Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-α in human ER-positive breast cancer cells. Journal of Cellular Biochemistry 112:3, pages 761-772.
Crossref
Crossref
Józefa Węsierska-Gądek, Margarita Maurer, Nora Zulehner & Oxana Komina. (2011) Whether to target single or multiple CDKs for therapy? That is the question. Journal of Cellular Physiology 226:2, pages 341-349.
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Crossref
Józefa Węsierska-Gądek, Stefan Hackl, Nora Zulehner, Margarita Maurer & Oxana Komina. (2011) Reconstitution of human MCF-7 breast cancer cells with caspase-3 does not sensitize them to action of CDK inhibitors. Journal of Cellular Biochemistry 112:1, pages 273-288.
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