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Patent Evaluations

Novel therapeutics based on inhibiting the interaction of glycogen phosphorylase and GL-subunit of glycogen-associated protein phosphatase 1: WO2009127723

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Pages 969-973 | Published online: 03 Apr 2010

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Nicolas Gaboriaud-Kolar & Alexios-Leandros Skaltsounis. (2013) Glycogen phosphorylase inhibitors: a patent review (2008 – 2012). Expert Opinion on Therapeutic Patents 23:8, pages 1017-1032.
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Articles from other publishers (5)

Mónica Ferreira, Monique Beullens, Mathieu Bollen & Aleyde Van Eynde. (2019) Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:1, pages 16-30.
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Jing Li, Wei-Tien ChangChang-Qing Li, Chunpei Lee, Hsien-Hao HuangChin-Wan HsuWen-Jone ChenXiangdong Zhu, Chong-Zhi Wang, Terry L. Vanden Hoek & Zuo-Hui Shao. (2017) Baicalein Preventive Treatment Confers Optimal Cardioprotection by PTEN/Akt/NO Activation. The American Journal of Chinese Medicine 45:05, pages 987-1001.
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László Juhász, Gergely Varga, Andrea Sztankovics, Ferenc Béke, Tibor Docsa, Attila Kiss‐Szikszai, Pál Gergely, Juraj Kóňa, Igor Tvaroška & László Somsák. (2014) Structure–Activity Relationships of Glycogen Phosphorylase Inhibitor FR258900 and Its Analogues: A Combined Synthetic, Enzyme Kinetics, and Computational Study. ChemPlusChem 79:11, pages 1558-1568.
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Gergely Varga, Tibor Docsa, Pál Gergely, László Juhász & László Somsák. (2013) Synthesis of tartaric acid analogues of FR258900 and their evaluation as glycogen phosphorylase inhibitors. Bioorganic & Medicinal Chemistry Letters 23:6, pages 1789-1792.
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Sofie De Munter, Maja Köhn & Mathieu Bollen. (2012) Challenges and Opportunities in the Development of Protein Phosphatase-Directed Therapeutics. ACS Chemical Biology 8:1, pages 36-45.
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