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JIANHONG CHEN, AGRIPINA G. DEACIUC, LINDA P. DWOSKIN, PETER A. CROOKS & DONGLU BAI. (2006) N, N –Disubstituted piperazines and homopiperazines: Synthesis and affinities at α4β2* and α7* neuronal nicotinic acetylcholine receptors. Journal of Enzyme Inhibition and Medicinal Chemistry 21:6, pages 667-680.
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Anatoly A. Mazurov, David C. Kombo, Terry A. Hauser, Lan Miao, Gary Dull, John F. Genus, Nikolai B. Fedorov, Lisa Benson, Serguei Sidach, Yunde Xiao, Philip S. Hammond, John W. James, Craig H. Miller & Daniel Yohannes. (2012)
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S
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R
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E. Lucas-Meunier, C. Monier, M. Amar, G. Baux, Y. Fregnac & P. Fossier. (2009) Involvement of Nicotinic and Muscarinic Receptors in the Endogenous Cholinergic Modulation of the Balance between Excitation and Inhibition in the Young Rat Visual Cortex. Cerebral Cortex 19:10, pages 2411-2427.
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Zhenfa Zhang, Guangrong Zheng, Marharyta Pivavarchyk, A.Gabriela Deaciuc, Linda P. Dwoskin & Peter A. Crooks. (2008) Tetrakis-azaaromatic quaternary ammonium salts: Novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters 18:21, pages 5753-5757.
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László Kursinszki, Krisztina Ludányi & Éva Szőke. (2008) LC-DAD and LC–MS–MS Analysis of Piperidine Alkaloids of Lobelia inflata L. (In Vitro and In Vivo). Chromatographia 68:S1, pages 27-33.
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Guangrong Zheng, Sangeetha P. Sumithran, Agripina G. Deaciuc, Linda P. Dwoskin & Peter A. Crooks. (2007) tris-Azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters 17:24, pages 6701-6706.
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Guangrong Zheng, Zhenfa Zhang, Marharyta Pivavarchyk, Agripina G. Deaciuc, Linda P. Dwoskin & Peter A. Crooks. (2007) Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation. Bioorganic & Medicinal Chemistry Letters 17:24, pages 6734-6738.
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Qi Sun, Cai-Qin Yue, Jia Ye, Chang-Ling Li, Tie-Ming Cheng & Run-Tao Li. (2007) Unique spirocyclopiperazinium salt III: Further investigation of monospirocyclopiperazinium (MSPZ) salts as potential analgesics. Bioorganic & Medicinal Chemistry Letters 17:22, pages 6245-6249.
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Linda P. Dwoskin, B. Matthew Joyce, Guangrong Zheng, Nichole M. Neugebauer, Vamshi K. Manda, Paul Lockman, Roger L. Papke, Michael T. Bardo & Peter A. Crooks. (2007) Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD). Biochemical Pharmacology 74:8, pages 1271-1282.
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William H. Bunnelle, Jerome F. Daanen, Keith B. Ryther, Michael R. Schrimpf, Michael J. Dart, Arianna Gelain, Michael D. Meyer, Jennifer M. Frost, David J. Anderson, Michael Buckley, Peter Curzon, Ying-Jun Cao, Pamela Puttfarcken, Xenia Searle, Jianguo Ji, C. Brent Putman, Carol Surowy, Lucio Toma & Daniela Barlocco. (2007)
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Lincoln H. Wilkins, Dennis K. Miller, Joshua T. Ayers, Peter A. Crooks & Linda P. Dwoskin. (2005) N-n-alkylnicotinium analogs, a novel class of antagonists at α4β2* Nicotinic acetylcholine receptors: Inhibition of S(-)-nicotine-evoked 86Rb+Efflux from rat thalamic synaptosomes. The AAPS Journal 7:4, pages E922-E930.
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Joshua T. Ayers, Aaron Clauset, Jeffrey D. Schmitt, Linda P. Dwoskin & Peter A. Crooks. (2005) Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the α4β2 nicotinic acetylcholine receptor subtype using nonlinear techniques. The AAPS Journal 7:3, pages E678-E685.
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Nicolas Leflemme, Patrick Dallemagne & Sylvain Rault. (2004) An efficient route to 6-(het)aryl-2-methyl-2,3-dihydro-1H-pyridin-4-ones as potential nAChRs ligands. Tetrahedron 60:22, pages 4861-4865.
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Linda P Dwoskin, Sangeetha P Sumithran, Jun Zhu, A.Gabriela Deaciuc, Joshua T Ayers & Peter A Crooks. (2004) Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents. Bioorganic & Medicinal Chemistry Letters 14:8, pages 1863-1867.
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Jing-Chao Dong, Xin Wang, Run-Tao Li, Hong-Mei Zhang, Tie-Ming Cheng & Chang-Ling Li. (2003) Synthesis and analgesic activity of hydrochlorides and quaternary ammoniums of epibatidine incorporated with amino acid ester. Bioorganic & Medicinal Chemistry Letters 13:24, pages 4327-4329.
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J. Zhu, P. A. Crooks, J. T. Ayers, S. P. Sumithran & L. P. Dwoskin. (2003)
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Vladimir P. Grinevich, Peter A. Crooks, Sangeetha P. Sumithran, Aaron J. Haubner, Joshua T. Ayers & Linda P. Dwoskin. (2003)
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Feng-Li Gao, Xin Wang, Hong-Mei Zhang, Tie-Ming Cheng & Run-Tao Li. (2003) Unique spirocyclopiperazinium salt I: synthesis and structure–Activity relationship of spirocyclopiperazinium salts as analgesics. Bioorganic & Medicinal Chemistry Letters 13:9, pages 1535-1537.
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E. Lucas-Meunier, P. Fossier, G. Baux & M. Amar. (2003) Cholinergic modulation of the cortical neuronal network. Pflügers Archiv - European Journal of Physiology 446:1, pages 17-29.
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David D. Allen, Paul R. Lockman, Karen E. Roder, Linda P. Dwoskin & Peter A. Crooks. (2003) Active Transport of High-Affinity Choline and Nicotine Analogs into the Central Nervous System by the Blood-Brain Barrier Choline Transporter. Journal of Pharmacology and Experimental Therapeutics 304:3, pages 1268-1274.
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Jianhong Chen, Seth Norrholm, Linda P. Dwoskin, Peter A. Crooks & Donglu Bai. (2003) N,N-Disubstituted piperazines: synthesis and affinities at α4β2∗ and α7∗ neuronal nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters 13:1, pages 97-100.
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Joshua T Ayers, Linda P Dwoskin, A.Gabriela Deaciuc, Vladimir P Grinevich, Jun Zhu & Peter A Crooks. (2002) bis-Azaaromatic quaternary ammonium analogues: ligands for α4β2* and α7* subtypes of neuronal nicotinic receptors. Bioorganic & Medicinal Chemistry Letters 12:21, pages 3067-3071.
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