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Review

Recent developments in the area of macrolide antibiotics

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Pages 403-425 | Published online: 25 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Barrie Wilkinson, Steven G Kendrew, Rose M Sheridan & Peter F Leadlay. (2003) Biosynthetic engineering of polyketide synthases. Expert Opinion on Therapeutic Patents 13:10, pages 1579-1606.
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Todd C Henninger. (2003) Recent progress in the field of macrolide antibiotics. Expert Opinion on Therapeutic Patents 13:6, pages 787-805.
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H. Abdelghaffar, H. Kirst, A. Soukri, C. Babin-Chevaye & M.-T. Labro. (2002) Structure-Activity Relationships Among 9-N-Alkyl Derivatives of Erythromycylamine and Their Effect on the Oxidative Burst of Human Neutrophils In Vitro . Journal of Chemotherapy 14:2, pages 132-139.
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Articles from other publishers (23)

Afifa, Nazim Hussain & Zulqarnain Baqar. 2023. Microbial Biomolecules. Microbial Biomolecules 375 403 .
Roberto G. S. Berlinck, Camila M. Crnkovic, Juliana R. Gubiani, Darlon I. Bernardi, Laura P. Ióca & Jairo I. Quintana-Bulla. (2022) The isolation of water-soluble natural products – challenges, strategies and perspectives. Natural Product Reports 39:3, pages 596-669.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 573 643 .
Herbert A. Kirst. 2001. Kirk-Othmer Encyclopedia of Chemical Technology. Kirk-Othmer Encyclopedia of Chemical Technology 1 15 .
Tomohiro Sugimoto, Tetsuya Tanikawa, Keiko Suzuki & Yukiko Yamasaki. (2012) Synthesis and structure–activity relationship of a novel class of 15-membered macrolide antibiotics known as ‘11a-azalides’. Bioorganic & Medicinal Chemistry 20:19, pages 5787-5801.
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Tomohiro Sugimoto & Tetsuya Tanikawa. (2010) Synthesis and Antibacterial Activity of a Novel Class of 15-Membered Macrolide Antibiotics, “11a-Azalides”. ACS Medicinal Chemistry Letters 2:3, pages 234-237.
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Dražen Pavlović, Andrea Fajdetić & Stjepan Mutak. (2010) Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials. Bioorganic & Medicinal Chemistry 18:24, pages 8566-8582.
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Dražen Pavlović & Stjepan Mutak. (2010) Synthesis and Structure−Activity Relationships of Novel 8a-Aza-8a-homoerythromycin A Ketolides. Journal of Medicinal Chemistry 53:15, pages 5868-5880.
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Arnold L. Demain. (2009) Antibiotics: Natural products essential to human health. Medicinal Research Reviews 29:6, pages 821-842.
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Bin Zhu, Brett A. Marinelli, Darren Abbanat, Barbara D. Foleno, Karen Bush & Mark J. Macielag. (2007) Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives. Bioorganic & Medicinal Chemistry Letters 17:14, pages 3900-3904.
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Bin Zhu, Brett A. Marinelli, Darren Abbanat, Barbara D. Foleno, Todd C. Henninger, Karen Bush & Mark J. Macielag. (2006) Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives. Bioorganic & Medicinal Chemistry Letters 16:4, pages 1054-1059.
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Bin Zhu, Amy Maden & Mark J. Macielag. (2005) Novel erythromycin A derivatives: synthesis of 11,12-benzoxazine ketolides. Tetrahedron Letters 46:11, pages 1783-1785.
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Arnold L. Demain & Lixin Zhang. 2005. Natural Products. Natural Products 3 29 .
Daniel Hunziker, Pierre-C Wyss, Peter Angehrn, Aranka Mueller, Hans-Peter Marty, Remy Halm, Laurenz Kellenberger, Veronique Bitsch, Gerard Biringer, Wolf Arnold, Andreas Stämpfli, Anne Schmitt-Hoffmann & Denis Cousot. (2004) Novel ketolide antibiotics with a fused five-membered lactone ring––synthesis, physicochemical and antimicrobial properties. Bioorganic & Medicinal Chemistry 12:13, pages 3503-3519.
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Jay C. Butler, Jeffrey L. Lennox, Linda K. McDougal, Joyce A. Sutcliffe, Amelia Tait‐Kamradt & Fred C. Tenover. (2003) Macrolide‐Resistant Pneumococcal Endocarditis and Epidural Abscess that Develop during Erythromycin Therapy. Clinical Infectious Diseases 36:2, pages e19-e25.
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Jesús Cortés, Javier Velasco, Graham Foster, Andrew P. Blackaby, Brian A. M. Rudd & Barrie Wilkinson. (2002) Identification and cloning of a type III polyketide synthase required for diffusible pigment biosynthesis in Saccharopolyspora erythraea ‡ . Molecular Microbiology 44:5, pages 1213-1224.
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Sabine Gaisser, Rachel Lill, James Staunton, Carmen Méndez, José Salas & Peter F. Leadlay. (2002) Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea. Molecular Microbiology 44:3, pages 771-781.
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Joyce A Sutcliffe & Roland Leclercq. 2002. Macrolide Antibiotics. Macrolide Antibiotics 281 317 .
Herbert A. Kirst. 2002. Macrolide Antibiotics. Macrolide Antibiotics 1 13 .
Herbert Kirst. 2001. Kirk-Othmer Encyclopedia of Chemical Technology. Kirk-Othmer Encyclopedia of Chemical Technology.
Sabine Gaisser, Rachel Lill, Gabriele Wirtz, Friederike Grolle, James Staunton & Peter F. Leadlay. (2008) New erythromycin derivatives from Saccharopolyspora erythraea using sugar O‐methyltransferases from the spinosyn biosynthetic gene cluster . Molecular Microbiology 41:5, pages 1223-1231.
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Joanne J. Bronson & John F. Barrett. 2001. 89 98 .
A. Tait-KamradtT. DaviesP. C. AppelbaumF. Depardieu, P. Courvalin, J. PetitpasL. WondrackA. WalkerM. R. Jacobs & J. Sutcliffe. (2000) Two New Mechanisms of Macrolide Resistance in Clinical Strains of Streptococcus pneumoniae from Eastern Europe and North America . Antimicrobial Agents and Chemotherapy 44:12, pages 3395-3401.
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