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Expert Opinion on Therapeutic Patents Volume 10, 2000 - Issue 4
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Review

Regulators of the anaphylatoxin C5a

Stephen M Taylor Department of Physiology and Pharmacology and Centre for Drug Design and Development, University of Queensland, Brisbane, Qld 4072, Australia. [email protected]
&
David P Fairlie Department of Physiology and Pharmacology and Centre for Drug Design and Development, University of Queensland, Brisbane, Qld 4072, Australia. [email protected]
Pages 449-458 | Published online: 25 Feb 2005

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Lavinia M Proctor, Trent M Woodruff & Stephen M Taylor. (2006) Recent developments in C5/C5a inhibitors. Expert Opinion on Therapeutic Patents 16:4, pages 445-458.
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Articles from other publishers (12)

Enrique L. Larghi, María A. Operto, Rene Torres & Teodoro S. Kaufman. (2009) New inhibitors of the complement system inspired in K76-COOH. A SAR study of filifolinol derivatives through modifications of the C3′ position. Bioorganic & Medicinal Chemistry Letters 19:21, pages 6172-6175.
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T.V. Arumugam, T.M. Woodruff, J.D. Lathia, P.K. Selvaraj, M.P. Mattson & S.M. Taylor. (2009) Neuroprotection in stroke by complement inhibition and immunoglobulin therapy. Neuroscience 158:3, pages 1074-1089.
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Hitesh J. Sanganee, Andrew Baxter, Simon Barber, Alastair J.H. Brown, Denise Grice, Fraser Hunt, Sarah King, David Laughton, Garry Pairaudeau, Bob Thong, Richard Weaver & John Unitt. (2009) Discovery of small molecule human C5a receptor antagonists. Bioorganic & Medicinal Chemistry Letters 19:4, pages 1143-1147.
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Julian Blagg, Charles Mowbray, David C. Pryde, Gary Salmon, Esther Schmid, David Fairman & Kevin Beaumont. (2008) Small, non-peptide C5a receptor antagonists: Part 1. Bioorganic & Medicinal Chemistry Letters 18:20, pages 5601-5604.
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Julian Blagg, Charles Mowbray, David Pryde, Gary Salmon, David Fairman, Esther Schmid & Kevin Beaumont. (2008) Small, non-peptide C5a receptor antagonists: Part 2. Bioorganic & Medicinal Chemistry Letters 18:20, pages 5605-5608.
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J. Kent Barbay, Yong Gong, Mieke Buntinx, Jian Li, Concha Claes, Pamela J. Hornby, Guy Van Lommen, Jean Van Wauwe & Wei He. (2008) Synthesis and characterization of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists. Bioorganic & Medicinal Chemistry Letters 18:8, pages 2544-2548.
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Jade S. Blakeney, Robert C. Reid, Giang T. Le & David P. Fairlie. (2007) Nonpeptidic Ligands for Peptide-Activated G Protein-Coupled Receptors. Chemical Reviews 107:7, pages 2960-3041.
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Mariana Useglio, Patricia M. Castellano, María A. Operto, René Torres & Teodoro S. Kaufman. (2006) Synthesis of 3H-spiro[benzofuran-2,1′-cyclohexane] derivatives from naturally occurring filifolinol and their classical complement pathway inhibitory activity. Bioorganic & Medicinal Chemistry Letters 16:19, pages 5097-5101.
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Stephen Taylor & David Fairlie. 2005. Structural Biology of the Complement System. Structural Biology of the Complement System 341 362 .
Thiruma V Arumugam, Ian A Shiels, Trent M Woodruff, D Neil Granger & Stephen M Taylor. (2004) THE ROLE OF THE COMPLEMENT SYSTEM IN ISCHEMIA-REPERFUSION INJURY. Shock 21:5, pages 401-409.
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Robert C. Reid, Giovanni Abbenante, Stephen M. Taylor & David P. Fairlie. (2003) A Convergent Solution-Phase Synthesis of the Macrocycle Ac-Phe-[Orn-Pro- d -Cha-Trp-Arg], a Potent New Antiinflammatory Drug . The Journal of Organic Chemistry 68:11, pages 4464-4471.
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Thiruma V. Arumugam, Ian A. Shiels, Trent M. Woodruff, Robert C. Reid, David P. Fairlie & Stephen M. Taylor. (2002) Protective Effect of a New C5a Receptor Antagonist against Ischemia–Reperfusion Injury in the Rat Small Intestine. Journal of Surgical Research 103:2, pages 260-267.
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