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Review

Non-camptothecin topoisomerase I active compounds as potential anticancer agents

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Pages 635-666 | Published online: 25 Feb 2005

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Daulat B Khadka & Won-Jea Cho. (2013) Topoisomerase inhibitors as anticancer agents: a patent update. Expert Opinion on Therapeutic Patents 23:8, pages 1033-1056.
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Wen Hou, Zhen-Ya Wang, Cheng-Kang Peng, Jing Lin, Xin Liu, Yi-Qun Chang, Jun Xu, Ren-Wang Jiang, Hui Lin, Ping-Hua Sun & Wei-Min Chen. (2016) Novel securinine derivatives as topoisomerase I based antitumor agents. European Journal of Medicinal Chemistry 122, pages 149-163.
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Niloy Kundu, Arpita Roy, Debasis Banik & Nilmoni Sarkar. (2016) Unveiling the Mode of Interaction of Berberine Alkaloid in Different Supramolecular Confined Environments: Interplay of Surface Charge between Nano-Confined Charged Layer and DNA. The Journal of Physical Chemistry B 120:6, pages 1106-1120.
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Xiaobei Pan, Janet M. Hartley, John A. Hartley, Kenneth N. White, Zhengtao Wang & S.W. Annie Bligh. (2012) Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells. Phytomedicine 19:7, pages 618-624.
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Satoshi Sunami, Teruyuki Nishimura, Ikuko Nishimura, Satoru Ito, Hiroharu Arakawa & Mitsuru Ohkubo. (2009) Synthesis and Biological Activities of Topoisomerase I Inhibitors, 6-Arylmethylamino Analogues of Edotecarin. Journal of Medicinal Chemistry 52:10, pages 3225-3237.
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Shanteri Singh, Jason G. McCoy, Changsheng Zhang, Craig A. Bingman, George N. PhillipsJr.Jr. & Jon S. Thorson. (2008) Structure and Mechanism of the Rebeccamycin Sugar 4′-O-Methyltransferase RebM. Journal of Biological Chemistry 283:33, pages 22628-22636.
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Geoffrey A. Cordell. 2008. 391 410 .
Hans-Joachim Knölker & Kethiri R Reddy. 2008. 181 193 .
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Gui-Qing Xu, Peng Guo, Chong Zhang, Qiao-Jun He, Bo Yang & Yong-Zhou Hu. (2007) Synthesis and Cytotoxicity of Indolopyrrolemaleimides. Chemical and Pharmaceutical Bulletin 55:9, pages 1302-1307.
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C.J. Thibodeaux, H.-W. Liu & J.S. Thorson. 2007. Comprehensive Glycoscience. Comprehensive Glycoscience 373 396 .
Herbert I. Hurwitz, Roger B. Cohen, J. Patrick McGovren, Samit Hirawat, William P. Petros, Yutaka Natsumeda & Tomoko Yoshinari. (2006) A phase I study of the safety and pharmacokinetics of edotecarin (J-107088), a novel topoisomerase I inhibitor, in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology 59:1, pages 139-147.
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Atsushi AkaoNobuaki NonoyamaToshiaki MaseNobuyoshi Yasuda. (2006) Development of Large-Scale Preparations of Indole Derivatives:  Evaluation of Potential Thermal Hazards and Studies of Reaction Kinetics and Mechanisms. Organic Process Research & Development 10:6, pages 1178-1183.
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Changsheng Zhang, Christoph Albermann, Xun Fu, Noel R. Peters, John D. Chisholm, Guisheng Zhang, Eric J. Gilbert, Peng George Wang, David L. Van Vranken & Jon S. Thorson. (2006) RebG- and RebM-Catalyzed Indolocarbazole Diversification. ChemBioChem 7:5, pages 795-804.
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Atsushi Akao, Kimihiko Sato, Nobuaki Nonoyama, Toshiaki Mase & Nobuyoshi Yasuda. (2006) Highly chemoselective reduction using a Rh/C–Fe(OAc)2 system: practical synthesis of functionalized indoles. Tetrahedron Letters 47:6, pages 969-972.
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César Sánchez, Carmen Méndez & José A. Salas. (2006) Indolocarbazole natural products: occurrence, biosynthesis, and biological activity. Nat. Prod. Rep. 23:6, pages 1007-1045.
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Stephen C. Pelly, Christopher J. Parkinson, Willem A. L. van Otterlo & Charles B. de Koning. (2005) Metathesis Reactions for the Synthesis of Ring-Fused Carbazoles. The Journal of Organic Chemistry 70:25, pages 10474-10481.
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Wolfgang Fröhner, Barbara Monse, Tobias M. Braxmeier, Laura Casiraghi, Heidi Sahagún & Pierfausto Seneci. (2005) Regiospecific Synthesis of Mono-N-substituted Indolopyrrolocarbazoles. Organic Letters 7:21, pages 4573-4576.
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Mark G. Saulnier, David R. Langley, David B. Frennesson, Byron H. Long, Stella Huang, Qi Gao, Dedong Wu, Craig R. Fairchild, Edward Ruediger, Kurt Zimmermann, Denis R. St. Laurent, Balu N. Balasubramanian & Dolatrai M. Vyas. (2005) Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3- a ]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp 3 Carbon . Organic Letters 7:7, pages 1271-1274.
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Jianji Wang, Nachimuthu Soundarajan, Nian Liu, Kurt Zimmermann & B. Narasimhulu Naidu. (2005) Highly convergent synthesis of a rebeccamycin analog with benzothioeno(2,3-a)pyrrolo(3,4-c)carbazole as the aglycone. Tetrahedron Letters 46:6, pages 907-910.
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Oliver Koepler, Stefania Mazzini, Maria Cristina Bellucci, Rosanna Mondelli, Angelika Baro, Sabine Laschat, Marc Hotfilder, Christophle Viseur & Wolfgang Frey. (2005) Synthesis and DNA binding properties of novel benzo[b]isoquino[2,3-h]-naphthyridines. Organic & Biomolecular Chemistry 3:15, pages 2848.
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Andrew Westwell. (2004) Monitor – chemistry. Drug Discovery Today 9:17, pages 769.
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. (2004) DNA Binding Mode of the Isoquinoline Alkaloid Berberine with the Deoxyoligonucleotide d(GCCGTCGTTTTACA) 2 . Bulletin of the Korean Chemical Society 25:4, pages 539-544.
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Pascale Moreau, Nathalie Gaillard, Christelle Marminon, Fabrice Anizon, Nathalie Dias, Brigitte Baldeyrou, Christian Bailly, Alain Pierré, John Hickman, Bruno Pfeiffer, Pierre Renard & Michelle Prudhomme. (2003) Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives. Bioorganic & Medicinal Chemistry 11:23, pages 4871-4879.
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Fabrice Anizon, Pascale Moreau, Martine Sancelme, William Laine, Christian Bailly & Michelle Prudhomme. (2003) Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety. Bioorganic & Medicinal Chemistry 11:17, pages 3709-3722.
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Stefania Mazzini, Maria Cristina Bellucci & Rosanna Mondelli. (2003) Mode of binding of the cytotoxic alkaloid berberine with the double helix oligonucleotide d(AAGAATTCTT)2. Bioorganic & Medicinal Chemistry 11:4, pages 505-514.
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Christian Bailly. (2003) Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs. Critical Reviews in Oncology/Hematology 45:1, pages 91-108.
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Jean-François Goossens, Jérôme Kluza, Hervé Vezin, Mustapha Kouach, Gilbert Briand, Brigitte Baldeyrou, Nicole Wattez & Christian Bailly. (2003) Plasma stability of two glycosyl indolocarbazole antitumor agents. Biochemical Pharmacology 65:1, pages 25-34.
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Amy Q. Wang, Wei Zeng, D. G. Musson, J. D. Rogers & A. L. Fisher. (2002) A rapid and sensitive liquid chromatography/negative ion tandem mass spectrometry method for the determination of an indolocarbazole in human plasma using internal standard (IS) 96-well diatomaceous earth plates for solid-liquid extraction. Rapid Communications in Mass Spectrometry 16:10, pages 975-981.
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Christelle Marminon, Michaël Facompré, Christian Bailly, John Hickman, Alain Pierré, Bruno Pfeiffer, Pierre Renard & Michelle Prudhomme. (2002) Dimers from dechlorinated rebeccamycin: synthesis, interaction with DNA, and antiproliferative activities. European Journal of Medicinal Chemistry 37:5, pages 435-440.
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Atsushi Akao, Shouichi Hiraga, Takehiko Iida, Asayuki Kamatani, Masashi Kawasaki, Toshiaki Mase, Takayuki Nemoto, Nobuya Satake, Steven A Weissman, David M Tschaen, Kai Rossen, Daniel Petrillo, Robert A Reamer & R.P Volante. (2001) Practical synthesis of a potent indolocarbazole-based, DNA topoisomerase inhibitor. Tetrahedron 57:43, pages 8917-8923.
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