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Expert Opinion on Therapeutic Patents Volume 12, 2002 - Issue 11
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Review

Small molecule corticotropin-releasing factor antagonists

Marion Lanier Neurocrine Biosciences, 10555 Science Center Drive, San Diego, CA 92121, USA
&
John P Williams Neurocrine Biosciences, 10555 Science Center Drive, San Diego, CA 92121, USA
Pages 1619-1630 | Published online: 25 Feb 2005

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Read on this site (4)

Marcelo Paez-Pereda, Felix Hausch & Florian Holsboer. (2011) Corticotropin releasing factor receptor antagonists for major depressive disorder. Expert Opinion on Investigational Drugs 20:4, pages 519-535.
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Paul J Gilligan. (2006) Corticotropin-releasing factor receptor antagonists. Expert Opinion on Therapeutic Patents 16:7, pages 913-924.
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Dimitri E Grigoriadis. (2005) The corticotropin-releasing factor receptor: a novel target for the treatment of depression and anxiety-related disorders. Expert Opinion on Therapeutic Targets 9:4, pages 651-684.
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Eric P Zorrilla & George F Koob. (2004) The therapeutic potential of CRF1 antagonists for anxiety. Expert Opinion on Investigational Drugs 13:7, pages 799-828.
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Articles from other publishers (11)

Wioletta Siemiradzka, Barbara Dolińska & Florian Ryszka. (2020) Influence of Concentration on Release and Permeation Process of Model Peptide Substance-Corticotropin-From Semisolid Formulations. Molecules 25:12, pages 2767.
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Takuto Kojima, Michiyo Mochizuki, Takafumi Takai, Yasutaka Hoashi, Sachie Morimoto, Masaki Seto, Minoru Nakamura, Katsumi Kobayashi, Yuu Sako, Maiko Tanaka, Naoyuki Kanzaki, Yohei Kosugi, Takahiko Yano & Kazuyoshi Aso. (2018) Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists. Bioorganic & Medicinal Chemistry 26:9, pages 2229-2250.
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D.E. Grigoriadis. 2017. Stress: Neuroendocrinology and Neurobiology. Stress: Neuroendocrinology and Neurobiology 57 65 .
William D. Schmitz, Allison B. Brenner, Joanne J. Bronson, Jonathan L. Ditta, Corrine R. Griffin, Yu-Wen Li, Nicholas J. Lodge, Thaddeus F. Molski, Richard E. Olson, Xiaoliang Zhuo & John E. Macor. (2010) 5-Arylamino-1,2,4-triazin-6(1H)-one CRF1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters 20:12, pages 3579-3583.
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Gary Tresadern, Daniele Bemporad & Trevor Howe. (2009) A comparison of ligand based virtual screening methods and application to corticotropin releasing factor 1 receptor. Journal of Molecular Graphics and Modelling 27:8, pages 860-870.
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Andreas StengelYvette Taché. (2009) Neuroendocrine Control of the Gut During Stress: Corticotropin-Releasing Factor Signaling Pathways in the Spotlight. Annual Review of Physiology 71:1, pages 219-239.
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Carolyn D. Dzierba, Richard A. Hartz & Joanne J. Bronson. 2008. 3 23 .
Sam R.J. Hoare, Brock T. Brown, Mark A. Santos, Siobhan Malany, Stephen F. Betz & Dimitri E. Grigoriadis. (2006) Single amino acid residue determinants of non-peptide antagonist binding to the corticotropin-releasing factor1 (CRF1) receptor. Biochemical Pharmacology 72:2, pages 244-255.
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Paul A. Keller, Adam McCluskey, Jody Morgan & Sean M. J. O'Connor. (2006) The Role of the HPA Axis in Psychiatric Disorders and CRF Antagonists as Potential Treatments. Archiv der Pharmazie 339:7, pages 346-355.
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Kevin J. Hodgetts, Taeyoung Yoon, Jianhua Huang, Michael Gulianello, Andrzej Kieltyka, Renee Primus, Robbin Brodbeck, Stéphane De Lombaert & Darı́o Doller. (2003) 2-Aryl-3,6-dialkyl-5-dialkylaminopyrimidin-4-ones as novel crf-1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters 13:15, pages 2497-2500.
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John H. Kehne, George D. Maynard, Stéphane De Lombaert & James E. Krause. 2003. 11 20 .

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