Advanced search
Publication Cover
Expert Opinion on Therapeutic Patents Volume 12, 2002 - Issue 11
Submit an article Journal homepage
48
Views
9
CrossRef citations to date
0
Altmetric
Review

Recent advances in the development of melanocortin-4 receptor agonists

Jason D Speake GlaxoSmithKline Research & Development, 5 Moore Drive, Research Triangle Park, NC 27709, USA, Email:
&
Michael J Bishop GlaxoSmithKline Research & Development, 5 Moore Drive, Research Triangle Park, NC 27709, USA, Email:
Pages 1631-1638 | Published online: 25 Feb 2005

Citations (9)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

. (2004) Novel ligands of melanocortin receptors. Expert Opinion on Therapeutic Patents 14:2, pages 261-267.
Read now

Articles from other publishers (8)

Chen Chen. 2007. Progress in Medicinal Chemistry Volume 45. Progress in Medicinal Chemistry Volume 45 111 167 .
Liang Z. Yan, David Flora, Patrick Edwards, David L. Smiley, Paul J. Emmerson, Hansen M. Hsiung, Robert Gadski, JeAnne Hertel, Mark L. Heiman, Saba Husain, Thomas P. O’Brien, Steven D. Kahl, Lianshan Zhang, Richard D. DiMarchi & John P. Mayer. (2005) Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold. Bioorganic & Medicinal Chemistry Letters 15:20, pages 4611-4614.
Crossref
Feroze Ujjainwalla, Daniel Warner, Christine Snedden, Ricky D. Grisson, Thomas F. Walsh, Matthew J. Wyvratt, Rubana N. Kalyani, Tanya MacNeil, Rui Tang, David H. Weinberg, Lex Van der Ploeg & Mark T. Goulet. (2005) Design and syntheses of melanocortin subtype-4 receptor agonists. Part 2: Discovery of the dihydropyridazinone motif. Bioorganic & Medicinal Chemistry Letters 15:18, pages 4023-4028.
Crossref
Brenda L. Palucki, Min K. Park, Ravi P. Nargund, Rui Tang, Tanya MacNeil, David H. Weinberg, Aurawan Vongs, Charles I. Rosenblum, George A. Doss, Randall R. Miller, Ralph A. Stearns, Qianping Peng, Constantin Tamvakopoulos, Lex H.T. Van der Ploeg & Arthur A. Patchett. (2005) 2-Piperazinecarboxamides as potent and selective melanocortin subtype-4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 15:8, pages 1993-1996.
Crossref
Brenda L. Palucki, Min K. Park, Ravi P. Nargund, Zhixiong Ye, Iyassu K. Sebhat, Patrick G. Pollard, Rubana N. Kalyani, Rui Tang, Tanya MacNeil, David H. Weinberg, Aurawan Vongs, Charles I. Rosenblum, George A. Doss, Randall R. Miller, Ralph A. Stearns, Qianping Peng, Constantin Tamvakopoulos, Erin McGowan, William J. Martin, Joseph M. Metzger, Cherrie A. Shepherd, Alison M. Strack, D. Euan MacIntyre, Lex H.T. Van der Ploeg & Arthur A. Patchett. (2005) Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist. Bioorganic & Medicinal Chemistry Letters 15:1, pages 171-175.
Crossref
Felikss Mutulis, Sviatlana Yahorava, Ilze Mutule, Aleh Yahorau, Edvards Liepinsh, Sergei Kopantshuk, Santa Veiksina, Kaspars Tars, Sergey Belyakov, Anatoly Mishnev, Ago Rinken & Jarl E. S. Wikberg. (2004) New Substituted Piperazines as Ligands for Melanocortin Receptors. Correlation to the X-ray Structure of “THIQ”. Journal of Medicinal Chemistry 47:18, pages 4613-4626.
Crossref
Réjean Ruel, Timothy F. Herpin, Lawrence Iben, Guanglin Luo, Alain Martel, Helen Mason, Gail Mattson, Brigitte Poirier, Edward H. Ruediger, Dan Shi, Carl Thibault, Guixue Yu, Ildiko Antal Zimanyi, Graham S. Poindexter & John E. Macor. (2003) β-Alanine dipeptides as MC4R agonists. Bioorganic & Medicinal Chemistry Letters 13:24, pages 4341-4344.
Crossref
Iyassu Sebhat, Zhixiong Ye, Maria Bednarek, David Weinberg, Ravi Nargund & Tung M. Fong. 2003. 31 40 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.