Citations (33)
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Anders Johansson. (2011) Recent progress in the discovery of melanin-concentrating hormone 1-receptor antagonists. Expert Opinion on Therapeutic Patents 21:6, pages 905-925.
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Guillaume J Hervieu. (2006) Further insights into the neurobiology of melanin-concentrating hormone in energy and mood balances. Expert Opinion on Therapeutic Targets 10:2, pages 211-229.
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Timothy J Kowalski & Mark D McBriar. (2004) Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity. Expert Opinion on Investigational Drugs 13:9, pages 1113-1122.
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Andrew Browning. (2004) Recent developments in the discovery of melanin-concentrating hormone antagonists: novel antiobesity agents. Expert Opinion on Therapeutic Patents 14:3, pages 313-325.
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Articles from other publishers (28)
Thomas Högberg, Thomas M. Frimurer & Pradip K. Sasmal. (2012) Melanin concentrating hormone receptor 1 (MCHR1) antagonists—Still a viable approach for obesity treatment?. Bioorganic & Medicinal Chemistry Letters 22:19, pages 6039-6047.
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Matthew D. Surman, Emily E. Freeman, James F. Grabowski, Mark Hadden, Alan J. Henderson, Guowei Jiang, Xiaowu (May) Jiang, Michele Luche, Yuri Khmelnitsky, Steven Vickers, Jean Viggers, Sharon Cheetham & Peter R. Guzzo. (2010) 5-(Pyridinon-1-yl)indazoles and 5-(furopyridinon-5-yl)indazoles as MCH-1 antagonists. Bioorganic & Medicinal Chemistry Letters 20:23, pages 7015-7019.
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Valérie Audinot, Odile Della Zuana, Nelly Fabry, Christine Ouvry, Olivier Nosjean, Jean-Michel Henlin, Jean-Luc Fauchère & Jean A. Boutin. (2009) S38151 [p-guanidinobenzoyl-[Des-Gly10]-MCH(7-17)] is a potent and selective antagonist at the MCH1 receptor and has anti-feeding properties in vivo. Peptides 30:11, pages 1997-2007.
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José L. Méndez-Andino & John A. Wos. (2007) MCH-R1 antagonists: what is keeping most research programs away from the clinic?. Drug Discovery Today 12:21-22, pages 972-979.
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Jing Su, Haiqun Tang, Brian A. McKittrick, Huizhong Gu, Tao Guo, Gang Qian, Duane A. Burnett, John W. Clader, William J. Greenlee, Brian E. Hawes, Kim O’Neill, Brian Spar, Blair Weig, Timothy Kowalski & Steve Sorota. (2007) Synthesis of novel bicyclo[4.1.0]heptane and bicyclo[3.1.0]hexane derivatives as melanin-concentrating hormone receptor R1 antagonists. Bioorganic & Medicinal Chemistry Letters 17:17, pages 4845-4850.
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Chien-An Chen, Yu Jiang, Kai Lu, Irena Daniewska, Christine G. Mazza, Leonardo Negron, Carlos Forray, Tony Parola, Boshan Li, Laxminarayan G. Hegde, Toni D. Wolinsky, Douglas A. Craig, Ron Kong, John M. Wetzel, Kim Andersen & Mohammad R. Marzabadi. (2007)
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Jing Su, Brian A. McKittrick, Haiqun Tang, Duane A. Burnett, John W. Clader, William J. Greenlee, Brian E. Hawes, Kim O’Neill, Brian Spar, Blair Weig, Timothy Kowalski, Steve Sorota, Cheng Li & Tongtong Liu. (2007) SAR study of bicyclo[4.1.0]heptanes as melanin-concentrating hormone receptor R1 antagonists: Taming hERG. Bioorganic & Medicinal Chemistry 15:16, pages 5369-5385.
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Rosa Arienzo, Sue Cramp, Hazel J. Dyke, Peter M. Lockey, Dennis Norman, Alan G. Roach, Phil Smith, Melanie Wong & Stephen P. Wren. (2007) Quinazoline and benzimidazole MCH-1R antagonists. Bioorganic & Medicinal Chemistry Letters 17:5, pages 1403-1407.
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José L. Méndez-Andino, Anny-Odile Colson, Kenneth M. Meyers, Maria C. Mitchell, Karen Hodge, Jeremy M. Howard, Nicholas Kim, David C. Ackley, Jerry K. Holbert, Scott W. Mittelstadt, Martin E. Dowty, Cindy M. Obringer, Paula Suchanek, Ofer Reizes, X. Eric Hu & John A. Wos. (2007) The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: A novel class of potent MCH-R1 antagonists. Bioorganic & Medicinal Chemistry 15:5, pages 2092-2105.
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Kenneth M. Meyers, José Méndez-Andino, Anny-Odile Colson, X. Eric Hu, John A. Wos, Maria C. Mitchell, Karen Hodge, Jeremy Howard, Jennifer L. Paris, Martin E. Dowty, Cindy M. Obringer & Ofer Reizes. (2007) Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists. Bioorganic & Medicinal Chemistry Letters 17:3, pages 657-661.
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Kenneth M. Meyers, Nicholas Kim, José L. Méndez-Andino, X. Eric Hu, Rashid N. Mumin, Sean R. Klopfenstein, John A. Wos, Maria C. Mitchell, Jennifer L. Paris, David C. Ackley, Jerry K. Holbert, Scott W. Mittelstadt & Ofer Reizes. (2007) Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists—Increasing selectivity over hERG. Bioorganic & Medicinal Chemistry Letters 17:3, pages 814-818.
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Kenneth M. Meyers, José L. Méndez-Andino, Anny-Odile Colson, Namal C. Warshakoon, John A. Wos, Maria C. Mitchell, Karen M. Hodge, Jeremy M. Howard, David C. Ackley, Jerry K. Holbert, Scott W. Mittelstadt, Martin E. Dowty, Cindy M. Obringer, Ofer Reizes & X. Eric Hu. (2007) Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists—Increasing selectivity over hERG. Bioorganic & Medicinal Chemistry Letters 17:3, pages 819-822.
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Francis X. Tavares, Kamal A. Al-Barazanji, Eric C. Bigham, Michael J. Bishop, Christy S. Britt, David L. Carlton, Paul L. Feldman, Aaron S. Goetz, Mary K. Grizzle, Yu C. Guo, Anthony L. Handlon, Donald L. Hertzog, Diane M. Ignar, Daniel G. Lang, Ronda J. Ott, Andrew J. Peat & Hui-Qiang Zhou. (2006) Potent, Selective, and Orally Efficacious Antagonists of Melanin-Concentrating Hormone Receptor 1. Journal of Medicinal Chemistry 49:24, pages 7095-7107.
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Sarah Hudson, Mehrak Kiankarimi, Martin W. Rowbottom, Troy D. Vickers, Dongpei Wu, Joseph Pontillo, Brett Ching, Wesley Dwight, Val S. Goodfellow, David Schwarz, Christopher E. Heise, Ajay Madan, Jenny Wen, William Ban, Hua Wang & Warren S. Wade. (2006) Synthesis and structure–activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 2. Bioorganic & Medicinal Chemistry Letters 16:18, pages 4922-4930.
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Martin W. Rowbottom, Troy D. Vickers, Brian Dyck, Jonathan Grey, Junko Tamiya, Mingzhu Zhang, Mehrak Kiankarimi, Dongpei Wu, Wesley Dwight, Warren S. Wade, David Schwarz, Christopher E. Heise, Ajay Madan, Andrew Fisher, Robert Petroski & Val S. Goodfellow. (2006) Synthesis and structure–activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1. Bioorganic & Medicinal Chemistry Letters 16:17, pages 4450-4457.
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Wen-Lian Wu, Duane A. Burnett, Richard Spring, Li Qiang, Thavalakulamgara K. Sasikumar, Martin S. Domalski, William J. Greenlee, Kim O’Neill & Brian E. Hawes. (2006) Synthesis and structure–activity relationships of piperidine-based melanin-concentrating hormone receptor 1 antagonists. Bioorganic & Medicinal Chemistry Letters 16:14, pages 3668-3673.
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Trond Ulven, Paul Brian Little, Jean-Marie Receveur, Thomas M. Frimurer, Øystein Rist, Pia K. Nørregaard & Thomas Högberg. (2006) 6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists: Structure–activity exploration of eastern and western parts. Bioorganic & Medicinal Chemistry Letters 16:4, pages 1070-1075.
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Andrew J. Peat, Paul L. Feldman, Dulce Garrido, Yu C. Guo & Donald L. Hertzog. (2006) A Novel One-Pot Synthesis of N-Substituted Thieno[3,2-d]pyrimidin-4(3H)-ones. HETEROCYCLES 70:1, pages 587.
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Anil Vasudevan, Matthew J. LaMarche, Christopher Blackburn, Jennifer Lee Che, Courtney A. Luchaco-Cullis, Sujen Lai, Thomas H. Marsilje, Michael A. Patane, Andrew J. Souers, Derek Wodka, Bradley Geddes, Sumiao Chen, Seven Brodjian, Doug H. Falls, Brian D. Dayton, Eugene Bush, Michael Brune, Robin D. Shapiro, Kennan C. Marsh, Lisa E. Hernandez, Hing L. Sham, Christine A. Collins & Philip R. Kym. (2005) Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists. Bioorganic & Medicinal Chemistry Letters 15:19, pages 4174-4179.
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Tao Guo, Yuefei Shao, Gang Qian, Laura L. Rokosz, Tara M. Stauffer, Rachael C. Hunter, Suresh D. Babu, Huizhong Gu & Doug W. Hobbs. (2005) Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis. Bioorganic & Medicinal Chemistry Letters 15:16, pages 3696-3700.
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Tao Guo, Rachael C. Hunter, Huizhong Gu, Laura L. Rokosz, Tara M. Stauffer & Doug W. Hobbs. (2005) Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis. Bioorganic & Medicinal Chemistry Letters 15:16, pages 3691-3695.
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Andrew J. Souers, Dariusz Wodka, Ju Gao, Jared C. Lewis, Anil Vasudevan, Robert Gentles, Sevan Brodjian, Brian Dayton, Christopher A. Ogiela, Dennis Fry, Lisa E. Hernandez, Kennan C. Marsh, Christine A. Collins & Philip R. Kym. (2004) Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1. Bioorganic & Medicinal Chemistry Letters 14:19, pages 4873-4877.
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