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Expert Opinion on Therapeutic Patents Volume 12, 2002 - Issue 5
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Miscellaneous

Therapeutic developments in matrix metalloproteinase inhibition

Prediman K Shah Atherosclerosis Research Centre, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Centre and UCLA School of Medicine, Los Angeles, California 90048, USA
,
Douglas J Wilkin Atherosclerosis Research Centre, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Centre and UCLA School of Medicine, Los Angeles, California 90048, USA
,
Terence M Doherty Atherosclerosis Research Centre, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Centre and UCLA School of Medicine, Los Angeles, California 90048, USA
,
Hiroyasu Uzui Atherosclerosis Research Centre, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Centre and UCLA School of Medicine, Los Angeles, California 90048, USA
,
Tripathi B Rajavashisth Atherosclerosis Research Centre, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Centre and UCLA School of Medicine, Los Angeles, California 90048, USA
,
Kamlesh Asotra Atherosclerosis Research Centre, Division of Cardiology, Department of Medicine, and the Burns and Allen Research Institute, Cedars-Sinai Medical Centre and UCLA School of Medicine, Los Angeles, California 90048, USA
&
Duanqing Pei Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455-0217, USA
 show all
Pages 665-707 | Published online: 25 Feb 2005

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Nian-Guang Li, Yu-Ping Tang, Jin-Ao Duan & Zhi-Hao Shi. (2014) Matrix metalloproteinase inhibitors: a patent review (2011 – 2013). Expert Opinion on Therapeutic Patents 24:9, pages 1039-1052.
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Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T Supuran. (2006) The sulfamide motif in the design of enzyme inhibitors. Expert Opinion on Therapeutic Patents 16:1, pages 27-47.
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Eli Breuer, Julia Frant & Reuven Reich. (2005) Recent non-hydroxamate matrix metalloproteinase inhibitors. Expert Opinion on Therapeutic Patents 15:3, pages 253-269.
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Ian M Clark & Andrew E Parker. (2003) Metalloproteinases: their role in arthritis and potential as therapeutic targets. Expert Opinion on Therapeutic Targets 7:1, pages 19-34.
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Richard D Connell. (2002) Patent focus on cancer chemotherapeutics V. Angiogenesis agents: September 2001 – August 2002. Expert Opinion on Therapeutic Patents 12:12, pages 1763-1782.
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Articles from other publishers (17)

Rayala Swetha, Chandrim Gayen, Devendra Kumar, Tryambak Deo Singh, Gyan Modi & Sushil Kumar Singh. (2018) Biomolecular basis of matrix metallo proteinase-9 activity. Future Medicinal Chemistry 10:9, pages 1093-1112.
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Hiroyasu Uzui, Hideki Hayashi, Izuru Nakae, Tetsuya Matsumoto, Hiroaki Uenishi, Hisae Hayasaki, Takayoshi Asaji, Shinobu Matsui, Kunihisa Miwa, Jong-Dae Lee, Hiroshi Tada, Tatsuya Sawamura & Masatoshi Fujita. (2014) Pitavastatin decreases serum LOX-1 ligand levels and MT1-MMP expression in CD14-positive mononuclear cells in hypercholesterolemic patients. International Journal of Cardiology 176:3, pages 1230-1232.
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Anna Maria Panico, Paola Vicini, Athina Geronikaki, Matteo Incerti, Venera Cardile, Lucia Crascì, Rossella Messina & Simone Ronsisvalle. (2011) Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation. Bioorganic Chemistry 39:1, pages 48-52.
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Ajay Kumar Chaudhary, Mamta Singh, Alok C Bharti, Kamlesh Asotra, Shanthy Sundaram & Ravi Mehrotra. (2010) Genetic polymorphisms of matrix metalloproteinases and their inhibitors in potentially malignant and malignant lesions of the head and neck. Journal of Biomedical Science 17:1.
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Stephen A. Kolodziej, Susan L. Hockerman, Gary A. DeCrescenzo, Joseph J. McDonald, Debbie A. Mischke, Grace E. Munie, Theresa R. Fletcher, Nathan Stehle, Craig Swearingen & Daniel P. Becker. (2010) MMP-13 selective isonipecotamide α-sulfone hydroxamates. Bioorganic & Medicinal Chemistry Letters 20:12, pages 3561-3564.
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JAI PARKASH & KAMLESH ASOTRA. (2010) Combinatorial intervention of prostaglandin E2 receptor and calcium sensing receptor to attenuate breast cancer cell proliferation, migration and bone metastasis. Experimental and Therapeutic Medicine 1:2, pages 227-231.
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Amnon Hoffman, Bashir Qadri, Julia Frant, Yiffat Katz, Sudhakar R. Bhusare, Eli Breuer, Rivka Hadar & Reuven Reich. (2008) Carbamoylphosphonate Matrix Metalloproteinase Inhibitors 6: cis -2-Aminocyclohexylcarbamoylphosphonic Acid, A Novel Orally Active Antimetastatic Matrix Metalloproteinase-2 Selective Inhibitor—Synthesis and Pharmacodynamic and Pharmacokinetic Analysis . Journal of Medicinal Chemistry 51:5, pages 1406-1414.
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Sameer Amin & Prediman K. Shah. 2008. Reperfusion Therapy for Acute Myocardial Infarction. Reperfusion Therapy for Acute Myocardial Infarction 15 28 .
Yue-Mei Zhang, Xiaodong Fan, Shyh-Ming Yang, Robert H. Scannevin, Sharon L. Burke, Kenneth J. Rhodes & Paul F. Jackson. (2008) Syntheses and in vitro evaluation of arylsulfone-based MMP inhibitors with heterocycle-derived zinc-binding groups (ZBGs). Bioorganic & Medicinal Chemistry Letters 18:1, pages 405-408.
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Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T. Supuran. (2006) Therapeutic potential of sulfamides as enzyme inhibitors. Medicinal Research Reviews 26:6, pages 767-792.
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Prediman K. Shah. (2005) Preservation of Cardiac Extracellular Matrix by Passive Myocardial Restraint. Circulation 112:9, pages 1245-1247.
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Masatake Sano, Ikuko Nishino, Kyoji Ueno & Hiroshi Kamimori. (2004) Assay of collagenase activity for native triple-helical collagen using capillary gel electrophoresis with laser-induced fluorescence detection. Journal of Chromatography B 809:2, pages 251-256.
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Franck Augé, William Hornebeck & Jean-Yves Laronze. (2004) A novel strategy for designing specific gelatinase A inhibitors: potential use to control tumor progression. Critical Reviews in Oncology/Hematology 49:3, pages 277-282.
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Terence M. Doherty, Lorraine A. Fitzpatrick, Aisha Shaheen, Tripathi B. Rajavashisth & Robert C. Detrano. (2004) Genetic Determinants of Arterial Calcification Associated With Atherosclerosis. Mayo Clinic Proceedings 79:2, pages 197-210.
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Prediman K Shah. (2003) Pathophysiology of plaque rupture and the concept of plaque stabilization. Cardiology Clinics 21:3, pages 303-314.
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S. J. Yan & E. A. G. Blomme. (2016) In Situ Zymography: A Molecular Pathology Technique to Localize Endogenous Protease Activity in Tissue Sections. Veterinary Pathology 40:3, pages 227-236.
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Hiroyasu UzuiAlice HarpfMing LiuTerence M. DohertyArun ShuklaNing-Ning ChaiPinky V. TripathiStefan JovingeDouglas J. WilkinKamlesh AsotraPrediman K. ShahTripathi B. Rajavashisth. (2002) Increased Expression of Membrane Type 3-Matrix Metalloproteinase in Human Atherosclerotic Plaque. Circulation 106:24, pages 3024-3030.
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