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Expert Opinion on Therapeutic Patents Volume 12, 2002 - Issue 6
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Miscellaneous

Perspectives in camptothecin development

Sergio Penco Sigma-Tau, Pomezia, Italy
,
Lucio Merlini Dipartimento di Scienze Molecolari Agroalimentari, Università di Milano, Milano, Italy
,
Franco Zunino Laboratorio di Chemioterapia e Farmacologia Antitumourale Preclinica, Istituto Nazionale dei Tumori, Via Venezian 1, I 20133 Milano, Italy; Tel: +39 0223 902 267; Fax: +39 0223 902 692; , E-mail: [email protected]
&
Sabrina Dallavalle Dipartimento di Scienze Molecolari Agroalimentari, Università di Milano, Milano, Italy
Pages 837-844 | Published online: 25 Feb 2005

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Laura Magazzini, Fabio Pammolli, Massimo Riccaboni & Maria Alessandra Rossi. (2009) Patent disclosure and R&D competition in pharmaceuticals. Economics of Innovation and New Technology 18:5, pages 467-486.
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Xungui He, Heyong Gao, Wei Lu & Junchao Cai. (2004) New Method for the Synthesis of 5‐Hydroxycamptothecin Derivatives. Synthetic Communications 34:23, pages 4285-4291.
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Franco Zunino & Graziella Pratesi. (2004) Camptothecins in clinical development. Expert Opinion on Investigational Drugs 13:3, pages 269-284.
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Richard W Versace. (2003) The silatecans, a novel class of lipophilic camptothecins. Expert Opinion on Therapeutic Patents 13:6, pages 751-760.
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Articles from other publishers (11)

Nataliya F. Lazareva, Viktor P. Baryshok & Igor M. Lazarev. (2018) Silicon-containing analogs of camptothecin as anticancer agents. Archiv der Pharmazie 351:1, pages 1700297.
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Chen Jin, Shuai Wen, Qiumeng Zhang, Qiwen Zhu, Jiahui Yu & Wei Lu. (2017) Synthesis and Biological Evaluation of Paclitaxel and Camptothecin Prodrugs on the Basis of 2-Nitroimidazole. ACS Medicinal Chemistry Letters 8:7, pages 762-765.
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Lei Wang, Ying Huang, Jie Zhang, Linjiang Tong, Yi Chen, Wei Lu & Qingqing Huang. (2014) Suzuki coupling based synthesis and in vitro cytotoxic evaluation of 7-heteroaryl-substituted camptothecin analogs. Bioorganic & Medicinal Chemistry Letters 24:6, pages 1597-1599.
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Lei Wang, Wei Yuan, Jie Zhang, Linjiang Tong, Yu Luo, Yi Chen, Wei Lu & Qingqing Huang. (2013) Synthesis of 7‐Triazole‐substituted Camptothecin via Click Chemistry and Evaluation of in vitro Antitumor Activity. Chinese Journal of Chemistry 32:2, pages 157-162.
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David G.I. Kingston. 2011. Cancer Management in Man: Chemotherapy, Biological Therapy, Hyperthermia and Supporting Measures. Cancer Management in Man: Chemotherapy, Biological Therapy, Hyperthermia and Supporting Measures 3 23 .
Yu Luo, Heyong Gao, Yunfei Li, Weigang Huang, Wei Lu & Zhaoguo Zhang. (2006) Copper-free Sonogashira reaction using 7-chloro camptothecins. Tetrahedron 62:11, pages 2465-2470.
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Sidney Hecht. 2005. Anticancer Agents from Natural Products. Anticancer Agents from Natural Products.
Mark S. Butler. (2005) Natural products to drugs: natural product derived compounds in clinical trials. Natural Product Reports 22:2, pages 162.
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Craig J. Thomas, Nicolas J. Rahier & Sidney M. Hecht. (2004) Camptothecin: current perspectives. Bioorganic & Medicinal Chemistry 12:7, pages 1585-1604.
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Nicolas J. Rahier, Brian M. Eisenhauer, Rong Gao, Shannon H. Jones & Sidney M. Hecht. (2004) Water-Soluble Camptothecin Derivatives that Are Intrinsic Topoisomerase I Poisons. Organic Letters 6:3, pages 321-324.
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M.E. Brewster, T. Loftsson & N. Bodor. (2004) Applications of chemically-modified cyclodextrins: use of hydroxypropyl-β-cyclodextrin as an enabling excipient for brain targeting, redox-based derivatives of estradiol A review of preclinical and clinical findings. Journal of Drug Delivery Science and Technology 14:1, pages 21-34.
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