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Selective androgen receptor modulators

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Pages 59-66 | Published online: 02 Mar 2005

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Xuqing Zhang, James C Lanter & Zhihua Sui. (2009) Recent advances in the development of selective androgen receptor modulators. Expert Opinion on Therapeutic Patents 19:9, pages 1239-1258.
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Youquan Xie, Yucheng Tian, Yuming Zhang, Zhisheng Zhang, Rui Chen, Mian Li, Jiawei Tang, Jinlei Bian, Zhiyu Li & Xi Xu. (2022) Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998–2021). European Journal of Medicinal Chemistry 230, pages 114119.
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Kiminori Ohta, Tokuhito Goto, Shinya Fujii, Masatoshi Kawahata, Akifumi Oda, Shigeru Ohta, Kentaro Yamaguchi, Shuichi Hirono & Yasuyuki Endo. (2011) Crystal structure, docking study and structure–activity relationship of carborane-containing androgen receptor antagonist 3-(12-hydroxymethyl-1,12-dicarba-closo-dodecaboran-1-yl)benzonitrile. Bioorganic & Medicinal Chemistry 19:11, pages 3540-3548.
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Tokuhito Goto, Kiminori Ohta, Shinya Fujii, Shigeru Ohta & Yasuyuki Endo. (2010) Design and Synthesis of Androgen Receptor Full Antagonists Bearing a p -Carborane Cage: Promising Ligands for Anti-Androgen Withdrawal Syndrome . Journal of Medicinal Chemistry 53:13, pages 4917-4926.
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Kiminori Ohta, Tokuhito Goto, Shinya Fijii, Tomoharu Suzuki, Shigeru Ohta & Yasuyuki Endo. (2008) Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring. Bioorganic & Medicinal Chemistry 16:17, pages 8022-8028.
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Xuqing Zhang, Xiaojie Li, George F. Allan, Tifanie Sbriscia, Olivia Linton, Scott G. Lundeen & Zhihua Sui. (2007) Design, Synthesis, and in Vivo SAR of a Novel Series of Pyrazolines as Potent Selective Androgen Receptor Modulators. Journal of Medicinal Chemistry 50:16, pages 3857-3869.
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Xuqing Zhang, George F. Allan, Tifanie Sbriscia, Olivia Linton, Scott G. Lundeen & Zhihua Sui. (2006) Synthesis and SAR of novel hydantoin derivatives as selective androgen receptor modulators. Bioorganic & Medicinal Chemistry Letters 16:22, pages 5763-5766.
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Xuqing Zhang, Xiaojie Li, George F. Allan, Amy Musto, Scott G. Lundeen & Zhihua Sui. (2006) Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands. Bioorganic & Medicinal Chemistry Letters 16:12, pages 3233-3237.
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S. H. Tariq, M. T. Haren, M. J. Kim & J. E. Morley. (2005) Andropause: Is the Emperor Wearing Any Clothes?. Reviews in Endocrine and Metabolic Disorders 6:2, pages 77-84.
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F. Chen, K. Knecht, C. Leu, S.J. Rutledge, A. Scafonas, C. Gambone, R. Vogel, H. Zhang, V. Kasparcova, C. Bai, S. Harada, A. Schmidt, A. Reszka & L. Freedman. (2004) Partial agonist/antagonist properties of androstenedione and 4-androsten-3β,17β-diol. The Journal of Steroid Biochemistry and Molecular Biology 91:4-5, pages 247-257.
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