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Review

Steroid sulfatase inhibitors

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Pages 605-625 | Published online: 02 Mar 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T Supuran. (2006) The sulfamide motif in the design of enzyme inhibitors. Expert Opinion on Therapeutic Patents 16:1, pages 27-47.
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Amarylla Horvath & Andreas Billich. (2005) Steroid sulfatase inhibitors. Expert Opinion on Therapeutic Patents 15:11, pages 1541-1553.
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Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T Supuran. (2004) Therapeutic applications of sulfamates. Expert Opinion on Therapeutic Patents 14:9, pages 1273-1308.
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Articles from other publishers (23)

Gauri alias Pooja M. Naik, Omkar D. ParadkarAarti M. Naik, Shamali S. Rane, Deepashree D. Dalvi, Saili S. Gad, Trupti S. Morajkar & Mohini T. Tawade. (2020) Recent Developments in Coumarin Derivatives for Breast Cancer Therapy. International Journal of Advanced Research in Science, Communication and Technology, pages 287-305.
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Xiaoye Sang, Hui Han, Donald Poirier & Sheng-Xiang Lin. (2018) Steroid sulfatase inhibition success and limitation in breast cancer clinical assays: An underlying mechanism. The Journal of Steroid Biochemistry and Molecular Biology 183, pages 80-93.
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A. Jameera Begam, S. Jubie & M.J. Nanjan. (2017) Estrogen receptor agonists/antagonists in breast cancer therapy: A critical review. Bioorganic Chemistry 71, pages 257-274.
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Jenny Roy, Julie Lefebvre, René Maltais & Donald Poirier. (2013) Inhibition of dehydroepiandosterone sulfate action in androgen-sensitive tissues by EM-1913, an inhibitor of steroid sulfatase. Molecular and Cellular Endocrinology 376:1-2, pages 148-155.
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René Maltais & Donald Poirier. (2011) Steroid sulfatase inhibitors: A review covering the promising 2000–2010 decade. Steroids 76:10-11, pages 929-948.
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Diane Fournier & Donald Poirier. (2011) Chemical synthesis and evaluation of 17α-alkylated derivatives of estradiol as inhibitors of steroid sulfatase. European Journal of Medicinal Chemistry 46:9, pages 4227-4237.
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René Maltais, Diane Fournier & Donald Poirier. (2009) Quantitative Structure‐Activity Relationship (QSAR) Study with a Series of 17α‐Derivatives of Estradiol: Model for the Development of Reversible Steroid Sulfatase Inhibitors. QSAR & Combinatorial Science 28:11-12, pages 1284-1299.
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Jean‐Yves Winum, Jean‐Louis Montero, Andrea Scozzafava & Claudiu T. Supuran. 2009. Drug Design of Zinc‐Enzyme Inhibitors. Drug Design of Zinc‐Enzyme Inhibitors 39 72 .
Diane Fournier & Donald Poirier. (2009) Estradiol dimers as a new class of steroid sulfatase reversible inhibitors. Bioorganic & Medicinal Chemistry Letters 19:3, pages 693-696.
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Donald Poirier. (2008) New cancer drugs targeting the biosynthesis of estrogens and androgens. Drug Development Research 69:6, pages 304-318.
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Hiroyuki Ishida, Taisuke Nakata, Masayo Suzuki, Yukimasa Shiotsu, Hideyuki Tanaka, Natsuko Sato, Yoko Terasaki, Miho Takebayashi, Hideharu Anazawa, Chikara Murakata, Pui-Kai Li, Takashi Kuwabara & Shiro Akinaga. (2007) A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models. Breast Cancer Research and Treatment 106:2, pages 215-227.
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Liviu C. Ciobanu & Donald Poirier. (2006) Synthesis of Libraries of 16β‐Aminopropyl Estradiol Derivatives for Targeting Two Key Steroidogenic Enzymes. ChemMedChem 1:11, pages 1249-1259.
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Jean-Yves Winum, Andrea Scozzafava, Jean-Louis Montero & Claudiu T. Supuran. (2006) Therapeutic potential of sulfamides as enzyme inhibitors. Medicinal Research Reviews 26:6, pages 767-792.
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Emma Denehy, Jonathan M. White & Spencer J. Williams. (2006) Ground state structures of sulfate monoesters and sulfamates reveal similar reaction coordinates for sulfuryl and sulfamyl transfer. Chem. Commun.:3, pages 314-316.
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Jean‐Yves Winum, Andrea Scozzafava, Jean‐Louis Montero & Claudiu T. Supuran. (2004) Sulfamates and their therapeutic potential. Medicinal Research Reviews 25:2, pages 186-228.
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Philipp Lehr, Andreas Billich, Barbara Wolff & Peter Nussbaumer. (2005) N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase. Bioorganic & Medicinal Chemistry Letters 15:4, pages 1235-1238.
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H John Smith & Claire Simons. 2004. Enzymes and Their Inhibitors. Enzymes and Their Inhibitors.
Erwin P. Schreiner & Andreas Billich. (2004) Estrone formate: a novel type of irreversible inhibitor of human steroid sulfatase. Bioorganic & Medicinal Chemistry Letters 14:19, pages 4999-5002.
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Andreas Billich, Josef G. Meingassner, Peter Nussbaumer, Sandrine Desrayaud, Charles Lam, Anthony Winiski & Erwin Schreiner. (2004) 6-[2-(Adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases. The Journal of Steroid Biochemistry and Molecular Biology 92:1-2, pages 29-37.
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Peter Nussbaumer & Andreas Billich. (2004) Steroid sulfatase inhibitors. Medicinal Research Reviews 24:4, pages 529-576.
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Erwin P. Schreiner, Barbara Wolff, Anthony P. Winiski & Andreas Billich. (2003) 6-(2-Adamantan-2-ylidene-hydroxybenzoxazole)- O -sulfamate: A potent non-steroidal irreversible inhibitor of human steroid sulfatase. Bioorganic & Medicinal Chemistry Letters 13:24, pages 4313-4316.
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Peter Nussbaumer, Anthony P. Winiski & Andreas Billich. (2003) Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6- O -Sulfamates:  Potent Inhibitors of Human Steroid Sulfatase . Journal of Medicinal Chemistry 46:23, pages 5091-5094.
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Peter Nussbaumer, Dieter Geyl, Amarylla Horvath, Philipp Lehr, Barbara Wolff & Andreas Billich. (2003) Nortropinyl-Arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase. Bioorganic & Medicinal Chemistry Letters 13:21, pages 3673-3677.
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