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Expert Opinion on Therapeutic Patents Volume 13, 2003 - Issue 6
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Review

The silatecans, a novel class of lipophilic camptothecins

Richard W Versace Oncology Department, Novartis Institute for Biomedical Research, Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, NJ 07936, USA. [email protected]
Pages 751-760 | Published online: 02 Mar 2005

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Firdoos Ahmad Sofi & Nahida Tabassum. (2023) Natural product inspired leads in the discovery of anticancer agents: an update. Journal of Biomolecular Structure and Dynamics 41:17, pages 8605-8628.
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Daulat B Khadka & Won-Jea Cho. (2013) Topoisomerase inhibitors as anticancer agents: a patent update. Expert Opinion on Therapeutic Patents 23:8, pages 1033-1056.
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Articles from other publishers (8)

Maris A. Cinelli. (2018) Topoisomerase 1B poisons: Over a half‐century of drug leads, clinical candidates, and serendipitous discoveries. Medicinal Research Reviews 39:4, pages 1294-1337.
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Nataliya F. Lazareva, Viktor P. Baryshok & Igor M. Lazarev. (2018) Silicon-containing analogs of camptothecin as anticancer agents. Archiv der Pharmazie 351:1, pages 1700297.
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Karol Michał Kacprzak. 2013. Natural Products. Natural Products 643 682 .
Charles Dylan Turner & Marco A Ciufolini. (2011) Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D. Beilstein Journal of Organic Chemistry 7, pages 1475-1485.
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Corrado TringaliJimmy Orjala, Nicholas Oberlies, Cedric Pearce, Steven Swanson & A Kinghorn. 2011. Bioactive Compounds from Natural Sources, Second Edition. Bioactive Compounds from Natural Sources, Second Edition 37 64 .
Maris A. Cinelli, Andrew E. Morrell, Thomas S. Dexheimer, Keli Agama, Surbhi Agrawal, Yves Pommier & Mark Cushman. (2010) The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode. Bioorganic & Medicinal Chemistry 18:15, pages 5535-5552.
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Iñaki F. Trocòniz, María J. Garrido, Cristina Segura, Josep-María Cendrós, Paola Principe, Concepción Peraire & Rosendo Obach. (2005) Phase I dose-finding study and a pharmacokinetic/pharmacodynamic analysis of the neutropenic response of intravenous diflomotecan in patients with advanced malignant tumours. Cancer Chemotherapy and Pharmacology 57:6, pages 727-735.
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Mark S. Butler. (2005) Natural products to drugs: natural product derived compounds in clinical trials. Natural Product Reports 22:2, pages 162.
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