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Review

Histone deacetylase inhibitors: a survey of recent patents

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Pages 1677-1690 | Published online: 28 Nov 2005

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Haishan Wang & Brian W Dymock. (2009) New patented histone deacetylase inhibitors. Expert Opinion on Therapeutic Patents 19:12, pages 1727-1757.
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Steve Price & Hazel J Dyke. (2007) Histone deacetylase inhibitors. Expert Opinion on Therapeutic Patents 17:7, pages 745-765.
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Articles from other publishers (13)

Maurício Temotheo Tavares, Larissa Costa de Almeida, Thales Kronenberger, Glaucio Monteiro Ferreira, Thainá Fujii de Divitiis, Mônica Franco Zannini Junqueira Toledo, Neuza Mariko Aymoto Hassimotto, João Agostinho Machado-Neto, Letícia Veras Costa-Lotufo & Roberto Parise-Filho. (2021) Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry 35, pages 116085.
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Yusuf Oloruntoyin Ayipo, Mohd Nizam Mordi, Muzaimi Mustapha & Thenmoly Damodaran. (2021) Neuropharmacological potentials of β-carboline alkaloids for neuropsychiatric disorders. European Journal of Pharmacology 893, pages 173837.
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Pakit Kumboonma, Thanaset Senawong, Somprasong Saenglee, Chavi Yenjai & Chanokbhorn Phaosiri. (2017) Identification of phenolic compounds from Zingiber offinale and their derivatives as histone deacetylase inhibitors and antioxidants. Medicinal Chemistry Research 26:3, pages 650-661.
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Murtuza Hadianawala & Bhaskar Datta. (2016) Design and development of sulfonylurea derivatives as zinc metalloenzyme modulators. RSC Advances 6:11, pages 8923-8929.
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Florian Thaler. (2012) Current trends in the development of histone deacetylase inhibitors: a review of recent patent applications. Pharmaceutical Patent Analyst 1:1, pages 75-90.
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Paul A. Marks. (2010) Histone deacetylase inhibitors: A chemical genetics approach to understanding cellular functions. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1799:10-12, pages 717-725.
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Matthias Körner & Ulrich Tibes. 2008. Progress in Medicinal Chemistry Volume 46. Progress in Medicinal Chemistry Volume 46 205 280 .
Yukihiro Itoh, Takayoshi Suzuki, Akiyasu Kouketsu, Nobuaki Suzuki, Satoko Maeda, Minoru Yoshida, Hidehiko Nakagawa & Naoki Miyata. (2007) Design, Synthesis, Structure−Selectivity Relationship, and Effect on Human Cancer Cells of a Novel Series of Histone Deacetylase 6-Selective Inhibitors. Journal of Medicinal Chemistry 50:22, pages 5425-5438.
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Daniel Riester, Christian Hildmann & Andreas Schwienhorst. (2007) Histone deacetylase inhibitors—turning epigenic mechanisms of gene regulation into tools of therapeutic intervention in malignant and other diseases. Applied Microbiology and Biotechnology 75:3, pages 499-514.
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Steve Price, Walter Bordogna, Richard J. Bull, David E. Clark, Peter H. Crackett, Hazel J. Dyke, Matthew Gill, Neil V. Harris, Julia Gorski, Julia Lloyd, Peter M. Lockey, Julia Mullett, Alan G. Roach, Fabien Roussel & Anne B. White. (2007) Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry Letters 17:2, pages 370-375.
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Steve Price, Walter Bordogna, Ruth Braganza, Richard J. Bull, Hazel J. Dyke, Sophie Gardan, Matthew Gill, Neil V. Harris, Robert A. Heald, Marco van den Heuvel, Peter M. Lockey, Julia Lloyd, Aranzazu G. Molina, Alan G. Roach, Fabien Roussel, Jonathan M. Sutton & Anne B. White. (2007) Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry Letters 17:2, pages 363-369.
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Dominic Brittain, Hilmar Weinmann & Eckhard Ottow. 2007. Annual Reports in Medicinal Chemistry Volume 42. Annual Reports in Medicinal Chemistry Volume 42 337 348 .
Takayoshi Suzuki, Akiyasu Kouketsu, Yukihiro Itoh, Shinya Hisakawa, Satoko Maeda, Minoru Yoshida, Hidehiko Nakagawa & Naoki Miyata. (2006) Highly Potent and Selective Histone Deacetylase 6 Inhibitors Designed Based on a Small-Molecular Substrate. Journal of Medicinal Chemistry 49:16, pages 4809-4812.
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