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Review

Potential therapeutic applications of farnesoid X receptor (FXR) modulators

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Pages 333-341 | Published online: 28 Feb 2006

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Read on this site (3)

Valentina Sepe, Eleonora Distrutti, Stefano Fiorucci & Angela Zampella. (2018) Farnesoid X receptor modulators 2014-present: a patent review. Expert Opinion on Therapeutic Patents 28:5, pages 351-364.
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Valentina Sepe, Eleonora Distrutti, Stefano Fiorucci & Angela Zampella. (2015) Farnesoid X receptor modulators (2011 – 2014): a patent review. Expert Opinion on Therapeutic Patents 25:8, pages 885-896.
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Matthew Lantz Crawley. (2010) Farnesoid X receptor modulators: a patent review. Expert Opinion on Therapeutic Patents 20:8, pages 1047-1057.
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Articles from other publishers (7)

Deyamira Matuz-Mares, Héctor Vázquez-Meza & María Magdalena Vilchis-Landeros. (2022) NOX as a Therapeutic Target in Liver Disease. Antioxidants 11:10, pages 2038.
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Tadeja Režen, Damjana Rozman, Tünde Kovács, Patrik Kovács, Adrienn Sipos, Péter Bai & Edit Mikó. (2022) The role of bile acids in carcinogenesis. Cellular and Molecular Life Sciences 79:5.
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Roberto Pellicciari, Daniela Passeri, Francesca De Franco, Serena Mostarda, Paolo Filipponi, Carolina Colliva, Raffaella Maria Gadaleta, Placido Franco, Andrea Carotti, Antonio Macchiarulo, Aldo Roda, Antonio Moschetta & Antimo Gioiello. (2016) Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders. Journal of Medicinal Chemistry 59:19, pages 9201-9214.
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Roberto Pellicciari, Antimo Gioiello, Paola Sabbatini, Francesco Venturoni, Roberto Nuti, Carolina Colliva, Giovanni Rizzo, Luciano Adorini, Mark Pruzanski, Aldo Roda & Antonio Macchiarulo. (2012) Avicholic Acid: A Lead Compound from Birds on the Route to Potent TGR5 Modulators. ACS Medicinal Chemistry Letters 3:4, pages 273-277.
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Antimo Gioiello, Antonio Macchiarulo, Andrea Carotti, Paolo Filipponi, Gabriele Costantino, Giovanni Rizzo, Luciano Adorini & Roberto Pellicciari. (2011) Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-amine. Bioorganic & Medicinal Chemistry 19:8, pages 2650-2658.
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Káthia M. Honório, Richard C. Garratt, Igor Polikarpov & Adriano D. Andricopulo. (2007) 3D QSAR comparative molecular field analysis on nonsteroidal farnesoid X receptor activators. Journal of Molecular Graphics and Modelling 25:6, pages 921-927.
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Peter T. Meinke, Harold B. Wood & Jason W. Szewczyk. 2006. Annual Reports in Medicinal Chemistry Volume 41. Annual Reports in Medicinal Chemistry Volume 41 99 126 .

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