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Expert Opinion on Therapeutic Patents Volume 16, 2006 - Issue 6
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Review

Progress in acetylcholinesterase inhibitors for Alzheimer’s disease

Maria Laura Bolognesi University of Bologna, Department of Pharmaceutical Sciences, Alma Mater Studiorum, Via Belmeloro 6, I-40126 Bologna, ItalyE-mail: [email protected]
,
Anna Minarini University of Bologna, Department of Pharmaceutical Sciences, Alma Mater Studiorum, Via Belmeloro 6, I-40126 Bologna, Italy. [email protected]
,
Vincenzo Tumiatti University of Bologna, Department of Pharmaceutical Sciences, Alma Mater Studiorum, Via Belmeloro 6, I-40126 Bologna, Italy. [email protected]
&
Carlo Melchiorre University of Bologna, Department of Pharmaceutical Sciences, Alma Mater Studiorum, Via Belmeloro 6, I-40126 Bologna, Italy. [email protected]
Pages 811-823 | Published online: 24 May 2006

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Arjan Blokland & Frank Boess. (2008) Use of behavioural and long-term potentiation models in the development of memory-improving drugs. Expert Opinion on Drug Discovery 3:9, pages 1067-1080.
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Vincenzo Tumiatti, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Andrea Milelli, Riccardo Matera & Carlo Melchiorre. (2008) Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update. Expert Opinion on Therapeutic Patents 18:4, pages 387-401.
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Martin Nimczick & Michael Decker. (2015) New Approaches in the Design and Development of Cannabinoid Receptor Ligands: Multifunctional and Bivalent Compounds. ChemMedChem 10:5, pages 773-786.
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Christophe Rochais, Cédric Lecoutey, Florence Gaven, Patrizia Giannoni, Katia Hamidouche, Damien Hedou, Emmanuelle Dubost, David Genest, Samir Yahiaoui, Thomas Freret, Valentine Bouet, François Dauphin, Jana Sopkova de Oliveira Santos, Céline Ballandonne, Sophie Corvaisier, Aurélie Malzert-Fréon, Remi Legay, Michel Boulouard, Sylvie Claeysen & Patrick Dallemagne. (2015) Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride . Journal of Medicinal Chemistry 58:7, pages 3172-3187.
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C. David Andersson, Nina Forsgren, Christine Akfur, Anders Allgardsson, Lotta Berg, Cecilia Engdahl, Weixing Qian, Fredrik Ekström & Anna Linusson. (2013) Divergent Structure–Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. Journal of Medicinal Chemistry 56:19, pages 7615-7624.
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David Genest, Christophe Rochais, Cédric Lecoutey, Jana Sopkova-de Oliveira Santos, Céline Ballandonne, Sabrina Butt-Gueulle, Remi Legay, Marc Since & Patrick Dallemagne. (2013) Design, synthesis and biological evaluation of novel indano- and thiaindano-pyrazoles with potential interest for Alzheimer's disease. MedChemComm 4:6, pages 925.
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Andrea Cavalli & Maria Laura Bolognesi. 2012. Polypharmacology in Drug Discovery. Polypharmacology in Drug Discovery 441 458 .
Cédric Lecoutey, Christophe Rochais, David Genest, Sabrina Butt-Gueulle, Céline Ballandonne, Sophie Corvaisier, Fabienne Dulin, Alban Lepailleur, Jana Sopkova-de Oliveira Santos & Patrick Dallemagne. (2012) Synthesis of dual AChE/5-HT4 receptor multi-target directed ligands. MedChemComm 3:5, pages 627.
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Ping Jia, Rong Sheng, Jing Zhang, Liang Fang, Qiaojun He, Bo Yang & Yongzhou Hu. (2009) Design, synthesis and evaluation of galanthamine derivatives as acetylcholinesterase inhibitors. European Journal of Medicinal Chemistry 44:2, pages 772-784.
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Michela RosiniElena SimoniManuela BartoliniAndrea CavalliLuisa CeccariniNicoleta PascuDavid W. McClymontAndrea TarozziMaria L. BolognesiAnna MinariniVincenzo TumiattiVincenza AndrisanoIan R. MellorCarlo Melchiorre. (2008) Inhibition of Acetylcholinesterase, β-Amyloid Aggregation, and NMDA Receptors in Alzheimer’s Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush. Journal of Medicinal Chemistry 51:15, pages 4381-4384.
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Andrea Cavalli, Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Vincenzo Tumiatti, Maurizio Recanatini & Carlo Melchiorre. (2008) Multi-target-Directed Ligands To Combat Neurodegenerative Diseases. Journal of Medicinal Chemistry 51:3, pages 347-372.
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. (2007) Current awareness in geriatric psychiatry. International Journal of Geriatric Psychiatry 22:1, pages 91-98.
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