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Luis Apaza Ticona, Ángel Rumbero Sánchez, Cristina Thiebaut Estrada & Olga M. Palomino. (2020) Identification of TRPV1 Ion Channels Agonists of Tropaeolum tuberosum in Human Skin Keratinocytes. Planta Medica 87:05, pages 383-394.
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Andras Garami, Yury P. Shimansky, Zoltan Rumbus, Robson C.L. Vizin, Nelli Farkas, Judit Hegyi, Zsolt Szakacs, Margit Solymar, Alexandra Csenkey, Dan A. Chiche, Ram Kapil, Donald J. Kyle, Wade D. Van Horn, Peter Hegyi & Andrej A. Romanovsky. (2020) Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis. Pharmacology & Therapeutics 208, pages 107474.
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Larry V. Pearce, Jihyae Ann, Peter M. Blumberg & Jeewoo Lee. (2019) Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level. Biomolecules & Therapeutics 27:5, pages 435-441.
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Hiromasa Oka, Koichi Yonezawa, Akio Kamikawa, Kazuhiro Ikegai, Norio Asai, Shohei Shirakami, Satoshi Miyamoto, Toshihiro Watanabe, Tetsuo Kiso, Yukihiro Takemoto, Seiji Tamura & Takahiro Kuramochi. (2018) Design, synthesis, and biological evaluation of novel biphenyl-4-carboxamide derivatives as orally available TRPV1 antagonists. Bioorganic & Medicinal Chemistry 26:12, pages 3716-3726.
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Discovery of (
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Laykea Tafesse, Toshiyuki Kanemasa, Noriyuki Kurose, Jianming Yu, Toshiyuki Asaki, Gang Wu, Yuka Iwamoto, Yoshitaka Yamaguchi, Chiyou Ni, John Engel, Naoki Tsuno, Aniket Patel, Xiaoming Zhou, Takuya Shintani, Kevin Brown, Tsuyoshi Hasegawa, Manjunath Shet, Yasuyoshi Iso, Akira Kato & Donald J. Kyle. (2014)
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Natalie A. Hawryluk, Jeffrey E. Merit, Alec D. Lebsack, Bryan J. Branstetter, Michael D. Hack, Nadia Swanson, Hong Ao, Michael P. Maher, Anindya Bhattacharya, Qi Wang, Jamie M. Freedman, Brian P. Scott, Alan D. Wickenden, Sandra R. Chaplan & J. Guy Breitenbucher. (2010) Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 20:23, pages 7137-7141.
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Scott D. Kuduk, Ronald K. Chang, Jenny M.-C. Wai, Christina N. Di Marco, Victoria Cofre, Robert M. DiPardo, Sean P. Cook, Matthew J. Cato, Aneta Jovanovska, Mark O. Urban, Michael Leitl, Robert H. Spencer, Stefanie A. Kane, George D. Hartman & Mark T. Bilodeau. (2009) Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3). Bioorganic & Medicinal Chemistry Letters 19:15, pages 4059-4063.
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Philip R. Kym, Michael E. Kort & Charles W. Hutchins. (2009) Analgesic potential of TRPV1 antagonists. Biochemical Pharmacology 78:3, pages 211-216.
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Dong Xiao, Anandan Palani, Robert Aslanian, Brian A. McKittrick, Andrew T. McPhail, Craig C. Correll, P. Tara Phelps, John C. Anthes & Diane Rindgen. (2009) Spiro-piperidine azetidinones as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 19:3, pages 783-787.
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Anindya Bhattacharya, Brian P. Scott, Nadia Nasser, Hong Ao, Michael P. Maher, Adrienne E. Dubin, Devin M. Swanson, Nigel P. Shankley, Alan D. Wickenden & Sandra R. Chaplan. (2007) Pharmacology and Antitussive Efficacy of 4-(3-Trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic Acid (5-Trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a Transient Receptor Potential Vanilloid 1 Antagonist in Guinea Pigs. Journal of Pharmacology and Experimental Therapeutics 323:2, pages 665-674.
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Michele C. Jetter, Mark A. Youngman, James J. McNally, Mark E. McDonnell, Sui-Po Zhang, Adrienne E. Dubin, Nadia Nasser, Ellen E. Codd, Christopher M. Flores & Scott L. Dax. (2007) Heteroaryl β-tetralin ureas as novel antagonists of human TRPV1. Bioorganic & Medicinal Chemistry Letters 17:22, pages 6160-6163.
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