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Expert Opinion on Therapeutic Patents Volume 16, 2006 - Issue 8
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Review

P2X receptor ligands and pain

Char-Chang Shieh Research Investigator, Dept. R4PM, Bldg. AP9A, Abbott Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. [email protected]
,
Michael F Jarvis Research Investigator, Dept. R4PM, Bldg. AP9A, Abbott Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. [email protected]
,
Chih-Hung Lee Research Investigator, Dept. R4PM, Bldg. AP9A, Abbott Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. [email protected]
&
Richard J Perner Research Investigator, Dept. R4PM, Bldg. AP9A, Abbott Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. [email protected]
Pages 1113-1127 | Published online: 26 Jul 2006

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Wayne E Childers, Adam M Gilbert, Jeffrey D Kennedy & Garth T Whiteside. (2008) Advances in the development of novel analgesics. Expert Opinion on Therapeutic Patents 18:9, pages 1027-1067.
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Articles from other publishers (16)

Yahya I. Asiri & Mohd. Zaheen Hassan. (2023) An overview of ion channels therapeutics in the treatment of pain. Arabian Journal of Chemistry 16:10, pages 105180.
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Yifan Deng, Dongdong Yuan, Zhizhao Deng, Jianfen Liang, Zhenye Zhang, Ziqing Hei & Xiang Li. (2023) Bone marrow‐derived mesenchymal stem cells attenuate complete Freund's a djuvant‐induced inflammatory pain by inhibiting the expression of P2X3 . Cell Proliferation.
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Zhenhui Luo, Tingting Wang, Zhenglang Zhang, Hekun Zeng, Mengqin Yi, Peiyang Li, Jiaqin Pan, Chunyan Zhu, Na Lin, Shangdong Liang, Alexei Verkhratsky & Hong Nie. (2023) Polyphyllin VI screened from Chonglou by cell membrane immobilized chromatography relieves inflammatory pain by inhibiting inflammation and normalizing the expression of P2X3 purinoceptor. Frontiers in Pharmacology 14.
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Yuemei Wang, Yuanbing Zhu, Junmeng Wang, Longcong Dong, Shuqing Liu, Sihui Li & Qiaofeng Wu. (2023) Purinergic signaling: A gatekeeper of blood-brain barrier permeation. Frontiers in Pharmacology 14.
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Carolina Ocanha Jorge, Graciana de Azambuja, Beatriz Botasso Gomes, Hayla Lourenço Rodrigues, Augusto Ducati Luchessi & Maria Cláudia Gonçalves de Oliveira-Fusaro. (2020) P2X3 receptors contribute to transition from acute to chronic muscle pain. Purinergic Signalling 16:3, pages 403-414.
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Reza Sharif-Naeini. (2020) Role of mechanosensitive ion channels in the sensation of pain. Journal of Neural Transmission 127:4, pages 407-414.
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Karl E. Johansson, Anne-Lie Ståhl, Ida Arvidsson, Sebastian Loos, Ashmita Tontanahal, Johan Rebetz, Milan Chromek, Ann-Charlotte Kristoffersson, Ludger Johannes & Diana Karpman. (2019) Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism. Scientific Reports 9:1.
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Emelie Flood, Céline Boiteux, Bogdan Lev, Igor Vorobyov & Toby W. Allen. (2019) Atomistic Simulations of Membrane Ion Channel Conduction, Gating, and Modulation. Chemical Reviews 119:13, pages 7737-7832.
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Geoffrey Burnstock. 2016. Pharmacological Mechanisms and the Modulation of Pain. Pharmacological Mechanisms and the Modulation of Pain 91 137 .
Geoffrey Burnstock. (2013) Purinergic mechanisms and pain—An update. European Journal of Pharmacology 716:1-3, pages 24-40.
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Kimiko Kobayashi, Hiroki Yamanaka & Koichi Noguchi. (2012) Expression of ATP receptors in the rat dorsal root ganglion and spinal cord. Anatomical Science International 88:1, pages 10-16.
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Rebecca J. Gum, Brian Wakefield & Michael F. Jarvis. (2011) P2X receptor antagonists for pain management: examination of binding and physicochemical properties. Purinergic Signalling 8:S1, pages 41-56.
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Geoffrey Burnstock & Alexei VerkhratskyGeoffrey Burnstock & Alexei Verkhratsky. 2012. Purinergic Signalling and the Nervous System. Purinergic Signalling and the Nervous System 583 625 .
B. Flittiger, M. Klapperstück, G. Schmalzing & F. Markwardt. (2010) Effects of protons on macroscopic and single-channel currents mediated by the human P2X7 receptor. Biochimica et Biophysica Acta (BBA) - Biomembranes 1798:5, pages 947-957.
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Geoffrey Burnstock. 2009. Sensory Nerves. Sensory Nerves 333 392 .
Linda R. Watkins, Mark R. Hutchinson, Erin D. Milligan & Steven F. Maier. (2007) “Listening” and “talking” to neurons: Implications of immune activation for pain control and increasing the efficacy of opioids. Brain Research Reviews 56:1, pages 148-169.
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