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Expert Opinion on Therapeutic Patents Volume 17, 2007 - Issue 8
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Review

Therapeutic potential of adenosine receptor antagonists and agonists

Neil J Press Novartis Institutes for Biomedical Research, Wimblehurst Road, Horsham, West Sussex, RH12 5AB, UK
,
Stefania Gessi Università degli Studi di Ferrara, Dipartimento di Medicina Clinica e Sperimentale-Sezione di Farmacologia, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy
,
Pier A Borea Università degli Studi di Ferrara, Dipartimento di Medicina Clinica e Sperimentale-Sezione di Farmacologia, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy
&
Riccardo Polosa University of Catania, Dipartimento di Medicina Interna e Specialistica, Ascoli-Tomaselli Hospitals, Via Passo Gravina, 187, 95125 Catania, Italy
Pages 979-991 | Published online: 16 Aug 2007

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Massimo Caruso, Angela Alamo, Emanuele Crisafulli, Cirino Raciti, Alfredo Fisichella & Riccardo Polosa. (2013) Adenosine signaling pathways as potential therapeutic targets in respiratory disease. Expert Opinion on Therapeutic Targets 17:7, pages 761-772.
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Stefania Gessi, Stefania Merighi, Debora Fazzi, Angela Stefanelli, Katia Varani & Pier Andrea Borea. (2011) Adenosine receptor targeting in health and disease. Expert Opinion on Investigational Drugs 20:12, pages 1591-1609.
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Neil J Press & John R Fozard. (2010) Progress towards novel adenosine receptor therapeutics gleaned from the recent patent literature. Expert Opinion on Therapeutic Patents 20:8, pages 987-1005.
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Articles from other publishers (20)

Trevor Simard, Richard Jung, Alisha Labinaz, Mohammad Ali Faraz, F. Daniel Ramirez, Pietro Di Santo, Ian Pitcher, Pouya Motazedian, Chantal Gaudet, Rebecca Rochman, Jeffrey Marbach, Paul Boland, Kiran Sarathy, Saleh Alghofaili, Juan J. Russo, Etienne Couture, Rob S. Beanlands & Benjamin Hibbert. (2019) Adenosine as a Marker and Mediator of Cardiovascular Homeostasis: A Translational Perspective. Cardiovascular & Hematological Disorders-Drug Targets 19:2, pages 109-131.
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K. Seo, J.W. Choi, D.-W. Kim, D. Han, S.J. Noh & H.S. Jung. (2017) Aminophylline Effect on Renal Ischemia-Reperfusion Injury in Mice. Transplantation Proceedings 49:2, pages 358-365.
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David M. Axelrod, Scott M. Sutherland, Andrew Anglemyer, Paul C. Grimm & Stephen J. Roth. (2016) A Double-Blinded, Randomized, Placebo-Controlled Clinical Trial of Aminophylline to Prevent Acute Kidney Injury in Children Following Congenital Heart Surgery With Cardiopulmonary Bypass*. Pediatric Critical Care Medicine 17:2, pages 135-143.
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Geoffrey Burnstock & Amir Pelleg. (2014) Cardiac purinergic signalling in health and disease. Purinergic Signalling 11:1, pages 1-46.
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David M. Axelrod, Andrew T. Anglemyer, Sara F. Sherman-Levine, Aihua Zhu, Paul C. Grimm, Stephen J. Roth & Scott M. Sutherland. (2014) Initial Experience Using Aminophylline to Improve Renal Dysfunction in the Pediatric Cardiovascular ICU. Pediatric Critical Care Medicine 15:1, pages 21-27.
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Chen Ning, Lin Qi, Jiaming Wen, Yujin Zhang, Weiru Zhang, Wei Wang, Michael Blackburn, Rodney Kellems & Yang Xia. (2012) Excessive Penile Norepinephrine Level Underlies Impaired Erectile Function in Adenosine A1 Receptor Deficient Mice. The Journal of Sexual Medicine 9:10, pages 2552-2561.
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Michal Tendera, Ewa Gaszewska-Żurek, Zofia Parma, Piotr Ponikowski, Ewa Jankowska, Kalina Kawecka-Jaszcz, Danuta Czarnecka, Maria Krzemińska-Pakuła, Zbigniew Bednarkiewicz, Maciej Sosnowski, Michael Ochan Kilama & Rahul Agrawal. (2012) The new oral adenosine A1 receptor agonist capadenoson in male patients with stable angina. Clinical Research in Cardiology 101:7, pages 585-591.
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Alessia Scatena, Francesco Fornai, Maria Letizia Trincavelli, Sabrina Taliani, Simona Daniele, Isabella Pugliesi, Sandro Cosconati, Claudia Martini & Federico Da Settimo. (2011) 3-(Fur-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3- a ]benzimidazol-4(10 H )-one, a Novel Adenosine Receptor Antagonist with A 2A -Mediated Neuroprotective Effects . ACS Chemical Neuroscience 2:9, pages 526-535.
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Stefania Gessi, Stefania Merighi, Valeria Sacchetto, Carolina Simioni & Pier Andrea Borea. (2011) Adenosine receptors and cancer. Biochimica et Biophysica Acta (BBA) - Biomembranes 1808:5, pages 1400-1412.
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Stefania Gessi, Stefania Merighi, Katia Varani & Pier Andrea Borea. 2011. Pharmacology of Purine and Pyrimidine Receptors. Pharmacology of Purine and Pyrimidine Receptors 41 75 .
John R. Fozard. 2010. A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics. A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics 3 26 .
Riccardo Polosa & Michael R. Blackburn. (2009) Adenosine receptors as targets for therapeutic intervention in asthma and chronic obstructive pulmonary disease. Trends in Pharmacological Sciences 30:10, pages 528-535.
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Anton V. Dolzhenko, Giorgia Pastorin, Anna V. Dolzhenko & Wai Keung Chui. (2009) A new synthesis of 2,8-disubstituted pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines. Tetrahedron Letters 50:40, pages 5617-5621.
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Wael Al Jaroudi & Ami E. Iskandrian. (2009) Regadenoson: A New Myocardial Stress Agent. Journal of the American College of Cardiology 54:13, pages 1123-1130.
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. (2009) Current World Literature. Current Opinion in Pulmonary Medicine 15:1, pages 79-87.
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Arvinder K. Dhalla, Jeffrey W. Chisholm, Gerald M. Reaven & Luiz Belardinelli. 2009. Adenosine Receptors in Health and Disease. Adenosine Receptors in Health and Disease 271 295 .
Trevor W. Stone, Stefania Ceruti & Mariapia P. Abbracchio. 2009. Adenosine Receptors in Health and Disease. Adenosine Receptors in Health and Disease 535 587 .
P.A. Borea, S. Gessi, S. Bar-Yehuda & P. Fishman. 2009. Adenosine Receptors in Health and Disease. Adenosine Receptors in Health and Disease 297 327 .
R Polosa. (2008) Finding better therapeutic targets for patients with asthma: adenosine receptors?. British Journal of Pharmacology 155:4, pages 441-443.
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G. Trifoglio Benfatto & R. Polosa. (2008) A2A adenosine receptor agonists for the treatment of asthma?. Allergy 63:8, pages 1086-1086.
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