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Therapeutic potential of A1 adenosine receptor ligands: a survey of recent patent literature

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Pages 677-691 | Published online: 19 Jun 2008

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Irene Giorgi & Paola Nieri. (2013) Adenosine A1 modulators: a patent update (2008 to present). Expert Opinion on Therapeutic Patents 23:9, pages 1109-1121.
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Manuela Jörg, Alisa Glukhova, Alaa Abdul-Ridha, Elizabeth A. Vecchio, Anh T. N. Nguyen, Patrick M. Sexton, Paul J. White, Lauren T. May, Arthur Christopoulos & Peter J. Scammells. (2016) Novel Irreversible Agonists Acting at the A 1 Adenosine Receptor . Journal of Medicinal Chemistry 59:24, pages 11182-11194.
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Dilip K. Tosh, Silvia Paoletta, Francesca Deflorian, Khai Phan, Steven M. Moss, Zhan-Guo Gao, Xiaohui Jiang & Kenneth A. Jacobson. (2012) Structural Sweet Spot for A 1 Adenosine Receptor Activation by Truncated (N)-Methanocarba Nucleosides: Receptor Docking and Potent Anticonvulsant Activity . Journal of Medicinal Chemistry 55:18, pages 8075-8090.
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Dilip K. Tosh, Khai Phan, Francesca Deflorian, Qiang Wei, Zhan-Guo Gao & Kenneth A. Jacobson. (2011) Truncated (N)-Methanocarba Nucleosides as A 1 Adenosine Receptor Agonists and Partial Agonists: Overcoming Lack of a Recognition Element . ACS Medicinal Chemistry Letters 2:8, pages 626-631.
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Nils Griebenow, Lars Bärfacker, Heinrich Meier, Dirk Schneider, Nicole Teusch, Klemens Lustig, Raimund Kast & Peter Kolkhof. (2010) Identification and optimization of substituted 5-aminopyrazoles as potent and selective adenosine A1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters 20:19, pages 5891-5894.
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Kenneth A. Jacobson. 2009. Adenosine Receptors in Health and Disease. Adenosine Receptors in Health and Disease 1 24 .

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