Citations (59)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Yoonji Lee, Sunhye Hong, Minghua Cui, Pankaz K Sharma, Jeewoo Lee & Sun Choi. (2015) Transient receptor potential vanilloid type 1 antagonists: a patent review (2011 – 2014). Expert Opinion on Therapeutic Patents 25:3, pages 291-318.
Read now
Read now
János Szolcsányi & Erika Pintér. (2013) Transient receptor potential vanilloid 1 as a therapeutic target in analgesia. Expert Opinion on Therapeutic Targets 17:6, pages 641-657.
Read now
Read now
Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Rosa Planells-Cases, Gregorio Fernández-Ballester, José Manuel González-Ros, Àngel Messeguer & Rosario González-Muñiz. (2012) Advances in modulating thermosensory TRP channels. Expert Opinion on Therapeutic Patents 22:9, pages 999-1017.
Read now
Read now
Articles from other publishers (56)
Yue Qiao, Yang Zhang, Zhenrui Qiao, Wenya He, Yingda Chen, Depu Song, Guohao Wang, Ning Guo, Lulian Shao, Zhiyong Tian, Qiang Wang, Lin Yan & Hai Qian. (2022) Discovery of (S)–N-(3-isopropylphenyl)-2-(5-phenylthiazol-2-yl)pyrrolidine-1-carboxamide as potent and brain-penetrant TRPV1 antagonist. European Journal of Medicinal Chemistry 233, pages 114191.
Crossref
Crossref
Jin Mi Kang, Sun Ok Kwon, Jihyae Ann, Sunho Lee, Changhoon Kim, Nayeon Do, Jin Ju Jeong, Peter M. Blumberg, Heejin Ha, Thi Ngoc Lan Vu, Sanghee Yoon, Sun Choi, Robert Frank-Foltyn, Bernhard Lesch, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2021) 2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 48, pages 128266.
Crossref
Crossref
Luis Apaza Ticona, Ángel Rumbero Sánchez, Cristina Thiebaut Estrada & Olga M. Palomino. (2020) Identification of TRPV1 Ion Channels Agonists of Tropaeolum tuberosum in Human Skin Keratinocytes. Planta Medica 87:05, pages 383-394.
Crossref
Crossref
Mircea Iftinca, Manon Defaye & Christophe Altier. (2020) TRPV1-Targeted Drugs in Development for Human Pain Conditions. Drugs 81:1, pages 7-27.
Crossref
Crossref
Jin Mi Kang, Sun Ok Kwon, Jihyae Ann, Peter M. Blumberg, Heejin Ha, Young Dong Yoo, Robert Frank-Foltyn, Bernhard Lesch, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2020) Discovery of 1-(1H-indazol-4-yl)-3-((1-phenyl-1H-pyrazol-5-yl)methyl) ureas as potent and thermoneutral TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 30:23, pages 127548.
Crossref
Crossref
Yiding Chen, Jingxi Mu, Min Zhu, Arjudeb Mukherjee & Hu Zhang. (2020) Transient Receptor Potential Channels and Inflammatory Bowel Disease. Frontiers in Immunology 11.
Crossref
Crossref
Songyeon Ahn, Yong Soo Kim, Myeong Seup Kim, Jihyae Ann, Heejin Ha, Young Dong Yoo, Young Ho Kim, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2020) Discovery of indane propanamides as potent and selective TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 30:3, pages 126838.
Crossref
Crossref
Larry V. Pearce, Jihyae Ann, Peter M. Blumberg & Jeewoo Lee. (2019) Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level. Biomolecules & Therapeutics 27:5, pages 435-441.
Crossref
Crossref
Changhoon Kim, Jihyae Ann, Sunho Lee, Wei Sun, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2018) Discovery of 2-(3,5-difluoro-4-methylsulfonaminophenyl)propanamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 28:14, pages 2539-2542.
Crossref
Crossref
Changhoon Kim, Jihyae Ann, Sunho Lee, Eunhye Kim, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2018) 4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands. Bioorganic & Medicinal Chemistry 26:15, pages 4509-4517.
Crossref
Crossref
Hiromasa Oka, Koichi Yonezawa, Akio Kamikawa, Kazuhiro Ikegai, Norio Asai, Shohei Shirakami, Satoshi Miyamoto, Toshihiro Watanabe, Tetsuo Kiso, Yukihiro Takemoto, Seiji Tamura & Takahiro Kuramochi. (2018) Design, synthesis, and biological evaluation of novel biphenyl-4-carboxamide derivatives as orally available TRPV1 antagonists. Bioorganic & Medicinal Chemistry 26:12, pages 3716-3726.
Crossref
Crossref
Seol Rin Park, Juhyun Kim, Sun Young Lee, Young-Ho Park & Hee-Doo Kim. (2018) 2-Methylacrylamide as a bioisoster of thiourea group for 1,3-dibenzylthioureido TRPV1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters 28:11, pages 2080-2083.
Crossref
Crossref
Chen Liao, Yan Liu, Chunxia Liu, Jiaqi Zhou, Huilan Li, Nasi Wang, Jieming Li, Taiyu Liu, Hesham Ghaleb, Wenlong Huang & Hai Qian. (2018) Phenylquinoline transient receptor potential vanilloid 1 antagonists for the treatment of pain: Discovery of 1-(2-phenylquinoline-4-carbonyl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide. Bioorganic & Medicinal Chemistry 26:4, pages 845-854.
Crossref
Crossref
Larry V. Pearce, Jihyae Ann, Aeran Jung, Shivaji A. Thorat, Brienna K. A. Herold, Amelework D. Habtemichael, Peter M. Blumberg & Jeewoo Lee. (2017) Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1). Journal of Medicinal Chemistry 60:19, pages 8246-8252.
Crossref
Crossref
Katsushi Kumata, Joji Yui, Yiding Zhang, Yusuke Kurihara, Masanao Ogawa, Wakana Mori, Masayuki Fujinaga & Ming-Rong Zhang. (2017) [ 11 C]BCTC: Radiosynthesis and in vivo binding to transient receptor potential vanilloid subfamily member 1 (TRPV1) receptor in the mouse trigeminal nerve. Bioorganic & Medicinal Chemistry Letters 27:19, pages 4521-4524.
Crossref
Crossref
Sunho Lee, Changhoon Kim, Jihyae Ann, Shivaji A. Thorat, Eunhye Kim, Jongmi Park, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2017) Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 27:18, pages 4383-4388.
Crossref
Crossref
Yelena Mostinski, Gilad Noy, Rakesh Kumar, Dmitry Tsvelikhovsky & Avi Priel. (2017) Tricyclic Spirolactones as Modular TRPV1 Synthetic Agonists. ACS Chemical Neuroscience 8:8, pages 1688-1696.
Crossref
Crossref
Sunho Lee, Dong Wook Kang, HyungChul Ryu, Changhoon Kim, Jihyae Ann, Hobin Lee, Eunhye Kim, Sunhye Hong, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2017) t-Butyl pyridine and phenyl C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry 25:8, pages 2451-2462.
Crossref
Crossref
Rajendra Kristam, Shashidhar N. Rao, Anne Sudha D’Cruz, Vijayalakshmi Mahadevan & Vellarkad N. Viswanadhan. (2017) TRPV1 antagonism by piperazinyl-aryl compounds: A Topomer-CoMFA study and its use in virtual screening for identification of novel antagonists. Journal of Molecular Graphics and Modelling 72, pages 112-128.
Crossref
Crossref
Jihyae Ann, Wei Sun, Xing Zhou, Aeran Jung, Jisoo Baek, Sunho Lee, Changhoon Kim, Suyoung Yoon, Sunhye Hong, Sun Choi, Noe A. Turcios, Brienna K.A. Herold, Timothy E. Esch, Nancy E. Lewin, Adelle Abramovitz, Larry V. Pearce, Peter M. Blumberg & Jeewoo Lee. (2016) Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template. Bioorganic & Medicinal Chemistry Letters 26:15, pages 3603-3607.
Crossref
Crossref
Tanisa Patcharatrakul & Sutep Gonlachanvit. (2016) Chili Peppers, Curcumins, and Prebiotics in Gastrointestinal Health and Disease. Current Gastroenterology Reports 18:4.
Crossref
Crossref
Jihyae Ann, Yooran Ki, Suyoung Yoon, Myeong Seop Kim, Jung-Un Lee, Changhoon Kim, Sunho Lee, Aeran Jung, Jisoo Baek, Sunhye Hong, Sun Choi, Larry V. Pearce, Timothy E. Esch, Noe A. Turcios, Nancy E. Lewin, Adebowale E. Ogunjirin, Brienna K.A. Herold, Anna K. McCall, Peter M. Blumberg & Jeewoo Lee. (2016) 2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry 24:6, pages 1231-1240.
Crossref
Crossref
Lin Yan, Jingjie Wang, Miaobo Pan, Qianqian Qiu, Wenlong Huang & Hai Qian. (2015)
Synthesis of Analogues of
BCTC
Incorporating a Pyrrolidinyl Linker and Biological Evaluation as Transient Receptor Potential Vanilloid 1 Antagonists
. Chemical Biology & Drug Design 87:2, pages 306-311.
Crossref
Crossref
Minghua Cui, Vijayakumar Gosu, Shaherin Basith, Sunhye Hong & Sun Choi. 2016. Ion channels as therapeutic targets, part B. Ion channels as therapeutic targets, part B
81
125
.
Jihyae Ann, Aeran Jung, Mi-Yeon Kim, Hyuk-Min Kim, HyungChul Ryu, Sunjoo Kim, Dong Wook Kang, Sunhye Hong, Minghua Cui, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2015) Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry 23:21, pages 6844-6854.
Crossref
Crossref
Phuong-Thao Tran, Ho Shin Kim, Jihyae Ann, Sung-Eun Kim, Changhoon Kim, Mannkyu Hong, Van-Hai Hoang, Van T.H. Ngo, Sunhye Hong, Minghua Cui, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Thomas Christoph & Jeewoo Lee. (2015) α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 25:11, pages 2326-2330.
Crossref
Crossref
HyungChul Ryu, Sejin Seo, Jee-Young Lee, Tae-Hwan Ha, Sunho Lee, Aeran Jung, Jihyae Ann, Sung-Eun Kim, Suyoung Yoon, Mannkyu Hong, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Klaus Schiene, Hannelore Stockhausen, Thomas Christoph, Sven Frormann & Jeewoo Lee. (2015) Pyridine C-region analogs of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists. European Journal of Medicinal Chemistry 93, pages 101-108.
Crossref
Crossref
Wei Sun, Hyo-Shin Kim, Sunho Lee, Aeran Jung, Sung-Eun Kim, Jihyae Ann, Suyoung Yoon, Sun Choi, Jin Hee Lee, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Klaus Schiene, Hannelore Stockhausen, Thomas Christoph, Sven Frormann & Jeewoo Lee. (2015) 6,6-Fused heterocyclic ureas as highly potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 25:4, pages 803-806.
Crossref
Crossref
Eric A. Voight, Arthur R. Gomtsyan, Jerome F. Daanen, Richard J. Perner, Robert G. Schmidt, Erol K. Bayburt, Stanley DiDomenico, Heath A. McDonald, Pamela S. Puttfarcken, Jun Chen, Torben R. Neelands, Bruce R. Bianchi, Ping Han, Regina M. Reilly, Pamela H. Franklin, Jason A. Segreti, Richard A. Nelson, Zhi Su, Andrew J. King, James S. Polakowski, Scott J. Baker, Donna M. Gauvin, LaGeisha R. Lewis, Joseph P. Mikusa, Shailen K. Joshi, Connie R. Faltynek, Philip R. Kym & Michael E. Kort. (2014)
Discovery of (
R
)-1-(7-Chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): A Temperature-Neutral Transient Receptor Potential Vanilloid-1 (TRPV1) Antagonist with Analgesic Efficacy
. Journal of Medicinal Chemistry 57:17, pages 7412-7424.
Crossref
Crossref
Laykea Tafesse, Toshiyuki Kanemasa, Noriyuki Kurose, Jianming Yu, Toshiyuki Asaki, Gang Wu, Yuka Iwamoto, Yoshitaka Yamaguchi, Chiyou Ni, John Engel, Naoki Tsuno, Aniket Patel, Xiaoming Zhou, Takuya Shintani, Kevin Brown, Tsuyoshi Hasegawa, Manjunath Shet, Yasuyoshi Iso, Akira Kato & Donald J. Kyle. (2014)
Structure–Activity Relationship Studies and Discovery of a Potent Transient Receptor Potential Vanilloid (TRPV1) Antagonist 4-[3-Chloro-5-[(1
S
)-1,2-dihydroxyethyl]-2-pyridyl]-
N
-[5-(trifluoromethyl)-2-pyridyl]-3,6-dihydro-2
H
-pyridine-1-carboxamide (V116517) as a Clinical Candidate for Pain Management
. Journal of Medicinal Chemistry 57:15, pages 6781-6794.
Crossref
Crossref
HyungChul Ryu, Sejin Seo, Seong-Hee Cho, Ho Shin Kim, Aeran Jung, Dong Wook Kang, Karam Son, Minghua Cui, Sun-hye Hong, Pankaz Kumar Sharma, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Hannelore Stockhausen, Klaus Schiene, Thomas Christoph, Sven Frormann & Jeewoo Lee. (2014) 2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 24:16, pages 4039-4043.
Crossref
Crossref
HyungChul Ryu, Sejin Seo, Myeong Seop Kim, Mi-Yeon Kim, Ho Shin Kim, Jihyae Ann, Phuong-Thao Tran, Van-Hai Hoang, Jieun Byun, Minghua Cui, Karam Son, Pankaz Kumar Sharma, Sun Choi, Peter M. Blumberg, Robert Frank-Foltyn, Gregor Bahrenberg, Babette-Yvonne Koegel, Thomas Christoph, Sven Frormann & Jeewoo Lee. (2014) 2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 24:16, pages 4044-4047.
Crossref
Crossref
Bernd Nilius & Arpad Szallasi. (2014) Transient Receptor Potential Channels as Drug Targets: From the Science of Basic Research to the Art of Medicine. Pharmacological Reviews 66:3, pages 676-814.
Crossref
Crossref
Ho Shin Kim, Mi-Kyoung Jin, Sang-Uk Kang, Ju-Ok Lim, Phuong-Thao Tran, Van-Hai Hoang, Jihyae Ann, Tae-Hwan Ha, Larry V. Pearce, Vladimir A. Pavlyukovets, Peter M. Blumberg & Jeewoo Lee. (2014) α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 24:12, pages 2685-2688.
Crossref
Crossref
Mary E. Bellizzi, Ashok V. Bhatia, Steven C. Cullen, Jorge Gandarilla, Albert W. Kruger & Dennie S. Welch. (2014)
Asymmetric Synthesis of a TRPV1 Antagonist via
tert
-Butanesulfinamide-Directed Reductive Amination with a Chromanone
. Organic Process Research & Development 18:2, pages 303-309.
Crossref
Crossref
Emmanuel Bourinet, Christophe Altier, Michael E. Hildebrand, Tuan Trang, Michael W. Salter & Gerald W. Zamponi. (2014) Calcium-Permeable Ion Channels in Pain Signaling. Physiological Reviews 94:1, pages 81-140.
Crossref
Crossref
Jennifer Victoria Bodkin & Elizabeth Soares Fernandes. (2013) TRPV1 and SP: key elements for sepsis outcome?. British Journal of Pharmacology 170:7, pages 1279-1292.
Crossref
Crossref
Tae-Hwan Ha, HyungChul Ryu, Sung-Eun Kim, Ho Shin Kim, Jihyae Ann, Phuong-Thao Tran, Van-Hai Hoang, Karam Son, Minghua Cui, Sun Choi, Peter M. Blumberg, Robert Frank, Gregor Bahrenberg, Klaus Schiene, Thomas Christoph, Sven Frormann & Jeewoo Lee. (2013) TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides. Bioorganic & Medicinal Chemistry 21:21, pages 6657-6664.
Crossref
Crossref
Rajendra Kristam, Vinod Parmar & Vellarkad N. Viswanadhan. (2013) 3D-QSAR analysis of TRPV1 inhibitors reveals a pharmacophore applicable to diverse scaffolds and clinical candidates. Journal of Molecular Graphics and Modelling 45, pages 157-172.
Crossref
Crossref
Stephen Zicha, Olivier Radresa, Patricia Laplante, Michael Morton, Karen Jones, Martin Main, Shephali Trivedi, Ron P. Julien, Andrew Griffin, Jean Labrecque, Sultan Ahmad & William Brown. (2013) Novel Methodology to Identify TRPV1 Antagonists Independent of Capsaicin Activation. SLAS Discovery 18:5, pages 544-555.
Crossref
Crossref
Shivaji A. Thorat, Dong Wook Kang, HyungChul Ryu, Myeong Seop Kim, Ho Shin Kim, Jihyae Ann, Taehwan Ha, Sung-Eun Kim, Karam Son, Sun Choi, Peter M. Blumberg, Robert Frank, Gregor Bahrenberg, Klaus Schiene, Thomas Christoph & Jeewoo Lee. (2013) 2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region. European Journal of Medicinal Chemistry 64, pages 589-602.
Crossref
Crossref
Abraham J. Nagy & Alan M. Rapoport. (2013) Update on future headache treatments. Neurological Sciences 34:S1, pages 101-108.
Crossref
Crossref
Frank Hevert, Sigrid Karrer, Philipp Babilas & Carola Berking. 2013. Fortschritte der praktischen Dermatologie und Venerologie 2012. Fortschritte der praktischen Dermatologie und Venerologie 2012
503
519
.
János Szolcsányi & Zoltán Sándor. (2012) Multisteric TRPV1 nocisensor: a target for analgesics. Trends in Pharmacological Sciences 33:12, pages 646-655.
Crossref
Crossref
Ismet Dorange, Rickard Forsblom, Istvan Macsari, Mats Svensson, Johan Bylund, Yevgeni Besidski, Jan Blid, Daniel Sohn & Ylva Gravenfors. (2012) Discovery of novel pyrrolopyridazine scaffolds as transient receptor potential vanilloid (TRPV1) antagonists. Bioorganic & Medicinal Chemistry Letters 22:22, pages 6888-6895.
Crossref
Crossref
Myeong Seop Kim, HyungChul Ryu, Dong Wook Kang, Seong-Hee Cho, Sejin Seo, Young Soo Park, Mi-Yeon Kim, Eun Joo Kwak, Yong Soo Kim, Rahul S. Bhondwe, Ho Shin Kim, Seul-gi Park, Karam Son, Sun Choi, Ian A. DeAndrea-Lazarus, Larry V. Pearce, Peter M. Blumberg, Robert Frank, Gregor Bahrenberg, Hannelore Stockhausen, Babette Y. Kögel, Klaus Schiene, Thomas Christoph & Jeewoo Lee. (2012)
2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure–Activity Relationships of 2-Amino Derivatives in the
N
-(6-Trifluoromethylpyridin-3-ylmethyl) C-Region
. Journal of Medicinal Chemistry 55:19, pages 8392-8408.
Crossref
Crossref
Rahul S. Bhondwe, Dong Wook Kang, Myeong Seop Kim, Ho Shin Kim, Seul-gi Park, Karam Son, Sun Choi, Krystle A. Lang Kuhs, Vladimir A. Pavlyukovets, Larry V. Pearce, Peter M. Blumberg & Jeewoo Lee. (2012) Structure–activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N′-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonism. Bioorganic & Medicinal Chemistry Letters 22:11, pages 3656-3660.
Crossref
Crossref
Wei Sun, Keliang Liu, HyungChul Ryu, Dong Wook Kang, Yong Soo Kim, Myeong Seop Kim, Yongsung Cho, Rahul S. Bhondwe, Shivaji A. Thorat, Ho Shin Kim, Larry V. Pearce, Vladimir A. Pavlyukovets, Richard Tran, Matthew A. Morgan, Jozsef Lazar, Christopher B. Ryder, Attila Toth, Peter M. Blumberg & Jeewoo Lee. (2012) 2-(4-Methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the B and C-regions. Bioorganic & Medicinal Chemistry 20:3, pages 1310-1318.
Crossref
Crossref
Yong Soo Kim, Min-Jung Kil, Sang-Uk Kang, HyungChul Ryu, Myeong Seop Kim, Yongsung Cho, Rahul S. Bhondwe, Shivaji A. Thorat, Wei Sun, Keliang Liu, Jin Hee Lee, Sun Choi, Larry V. Pearce, Vladimir A. Pavlyukovets, Matthew A. Morgan, Richard Tran, Jozsef Lazar, Peter M. Blumberg & Jeewoo Lee. (2012) N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure–activity relationships in the A-region. Bioorganic & Medicinal Chemistry 20:1, pages 215-224.
Crossref
Crossref
Michael E. Kort & Philip R. Kym. 2012. Progress in Medicinal Chemistry Volume 51. Progress in Medicinal Chemistry Volume 51
57
70
.
Paul Ratcliffe, Lynn Abernethy, Nasrin Ansari, Ken Cameron, Tom Clarkson, Maureen Dempster, David Dunn, Anna-Marie Easson, Darren Edwards, Katy Everett, Helen Feilden, Koc-Kan Ho, Steve Kultgen, Peter Littlewood, John Maclean, Duncan McArthur, Deborah McGregor, Hazel McLuskey, Irina Neagu, Olaf Nimz, Lesley-Anne Nisbet, Michael Ohlmeyer, Ronnie Palin, Quynhchi Pham, Yajing Rong, Andrew Roughton, Melanie Sammons, Robert Swanson, Heather Tracey & Glenn Walker. (2011) Discovery of potent, soluble and orally active TRPV1 antagonists. Structure–activity relationships of a series of isoxazoles. Bioorganic & Medicinal Chemistry Letters 21:15, pages 4652-4657.
Crossref
Crossref
Peter Holzer. (2011) Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system. Pharmacology & Therapeutics 131:1, pages 142-170.
Crossref
Crossref
Jes Olesen & Messoud Ashina. (2011) Emerging migraine treatments and drug targets. Trends in Pharmacological Sciences 32:6, pages 352-359.
Crossref
Crossref
Paul Ratcliffe, John Maclean, Lynn Abernethy, Tom Clarkson, Maureen Dempster, Anna-Marie Easson, Darren Edwards, Katy Everett, Helen Feilden, Peter Littlewood, Duncan McArthur, Deborah McGregor, Hazel McLuskey, Olaf Nimz, Lesley-Anne Nisbet, Ronnie Palin, Heather Tracey & Glenn Walker. (2011) Identification of potent, soluble, and orally active TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters 21:8, pages 2559-2563.
Crossref
Crossref
Thomas Ruzicka, Hans Wolff, Peter Thomas & Jörg Prinz. 2011. Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie
269
546
.
Kendall Mitchell, Brian D Bates, Jason M Keller, Matthew Lopez, Lindsey Scholl, Julia Navarro, Nicholas Madian, Gal Haspel, Michael I Nemenov & Michael J Iadarola. (2010) Ablation of Rat TRPV1-Expressing Adelta/C-Fibers with Resiniferatoxin: Analysis of Withdrawal Behaviors, Recovery of Function and Molecular Correlates. Molecular Pain 6, pages 1744-8069-6-94.
Crossref
Crossref