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Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review

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Pages 945-957 | Published online: 04 Apr 2011

Keep up to date with the latest research on this topic with citation updates for this article.

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Paolo Governa, Giulia Romagnoli, Paola Albanese, Federico Rossi, Fabrizio Manetti & Marco Biagi. (2023) Effect of in vitro simulated digestion on the anti-Helicobacter Pylori activity of different Propolis extracts. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Abdul Hameed, Mariya Al-Rashida, Maliha Uroos, Syeda Uroos Qazi, Sadia Naz, Marium Ishtiaq & Khalid Mohammed Khan. (2019) A patent update on therapeutic applications of urease inhibitors (2012–2018). Expert Opinion on Therapeutic Patents 29:3, pages 181-189.
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Abdul Hameed, Mariya al-Rashida, Maliha Uroos, Syed Abid Ali & Khalid Mohammed Khan. (2017) Schiff bases in medicinal chemistry: a patent review (2010-2015). Expert Opinion on Therapeutic Patents 27:1, pages 63-79.
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Laxman K. Adsul, Babasaheb P. Bandgar, Hemant V. Chavan, Shivkumar S. Jalde, Valmik D. Dhakane & Amol L. Shirfule. (2013) Synthesis and biological evaluation of novel series of aminopyrimidine derivatives as urease inhibitors and antimicrobial agents. Journal of Enzyme Inhibition and Medicinal Chemistry 28:6, pages 1316-1323.
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Rizwana Dilshad, Kashif-ur-Rehman Khan, Saeed Ahmad, Asif Ansari Shaik Mohammad, Asmaa E. Sherif, Huma Rao, Maqsood Ahmad, Bilal Ahmad Ghalloo & M. Yasmin Begum. (2023) Phytochemical characterization of Typha domingensis and the assessment of therapeutic potential using in vitro and in vivo biological activities and in silico studies. Frontiers in Chemistry 11.
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Arthika Manoharan, Jessica Farrell, Vina R. Aldilla, Greg Whiteley, Erik Kriel, Trevor Glasbey, Naresh Kumar, Kate H. Moore, Jim Manos & Theerthankar Das. (2023) N-acetylcysteine prevents catheter occlusion and inflammation in catheter associated-urinary tract infections by suppressing urease activity. Frontiers in Cellular and Infection Microbiology 13.
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Jalal Uddin, Saeed Ullah, Sobia Ahsan Halim, Muhammad Waqas, Aliya Ibrar, Imtiaz Khan, Abdullatif Bin Muhsinah, Ajmal Khan & Ahmed Al-Harrasi. (2023) Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment. ACS Omega 8:35, pages 31890-31898.
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