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Recent advances in the therapeutic applications of pyrazolines

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Pages 253-291 | Published online: 08 Mar 2012

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Tarfah Al-Warhi, Ahmed M El Kerdawy, Mohamed A Said, Amgad Albohy, Zainab M Elsayed, Nada Aljaeed, Eslam B Elkaeed, Wagdy M Eldehna, Hatem A Abdel-Aziz & Miral A Abdelmoaz. (2022) Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights. Drug Design, Development and Therapy 16, pages 1457-1471.
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Mohamed M. Hammouda, Heba M. Metwally, Ahmed Fekri & Johan Van der Eycken. (2021) Synthesis and Molecular Modeling Studies on Novel C2 Alkylated Benzoazonine Scaffold and Corresponding 2-Pyrazoline Derivatives as Acetylcholinestrase Enzyme Inhibitors. Polycyclic Aromatic Compounds 41:6, pages 1223-1240.
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Crossref
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Crossref
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Crossref
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Crossref
Sandip S. Pathade, Vishnu A. Adole & Bapu S. Jagdale. (2021) PEG-400 mediated synthesis, computational, antibacterial and antifungal studies of fluorinated pyrazolines. Current Research in Green and Sustainable Chemistry 4, pages 100172.
Crossref
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Crossref
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Crossref
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Crossref
Jing Tang, Dong‐Hui Xu, Xin Wang, Laicai Li, Xiang‐Yang Liu, Xin‐Tong Su, Jianmin Guo & Bin Zhai. (2020) A density functional theory study of the stereoselectivity of Cu( OTf ) 2 ‐catalyzed [3+2] cycloaddition of trifluoromethylated N ‐acylhydrazones and isoprene: A concerted asynchronous mechanism . International Journal of Quantum Chemistry 120:14.
Crossref
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Crossref
Mehlika Dilek Altıntop. (2020) Synthesis, In vitro and In silico Evaluation of a Series of Pyrazolines as New Anticholinesterase Agents. Letters in Drug Design & Discovery 17:5, pages 574-584.
Crossref
Ranju Bansal & Ranjit Singh. (2020) Steroidal pyrazolines as a promising scaffold in drug discovery. Future Medicinal Chemistry 12:10, pages 949-959.
Crossref
Safaa I. Elewa, Eman Mansour, Ibrahim F. Nassar & Amal A. I. Mekawey. (2020) Synthesis of Some New Pyrazoline-Based Thiazole Derivatives and Evaluation of Their Antimicrobial, Antifungal, and Anticancer Activities. Russian Journal of Bioorganic Chemistry 46:3, pages 382-392.
Crossref
Fatima Ezzahra Bennani, Latifa Doudach, Yahia Cherrah, Youssef Ramli, Khalid Karrouchi, M'hammed Ansar & My El Abbes Faouzi. (2020) Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line. Bioorganic Chemistry 97, pages 103470.
Crossref
Saba Farooq & Zainab Ngaini. (2020) One-Pot and Two-Pot Synthesis of Chalcone Based Mono and Bis-Pyrazolines. Tetrahedron Letters 61:4, pages 151416.
Crossref
Asmaa M. Fahim & Ahmad M. Farag. (2020) Synthesis, antimicrobial evaluation, molecular docking and theoretical calculations of novel pyrazolo[1,5-a]pyrimidine derivatives. Journal of Molecular Structure 1199, pages 127025.
Crossref
Mohammed Eddahmi, Nuno M. M. Moura, Latifa Bouissane, Ouafa Amiri, M. Amparo F. Faustino, José A. S. Cavaleiro, Ricardo F. Mendes, Filipe A. A. Paz, Maria G. P. M. S. Neves & El Mostapha Rakib. (2019) A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions. Molecules 25:1, pages 126.
Crossref
Belgin Sever, Mehlika Dilek Altıntop, Mohamed O. Radwan, Ahmet Özdemir, Masami Otsuka, Mikako Fujita & Halil I. Ciftci. (2019) Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors. European Journal of Medicinal Chemistry 182, pages 111648.
Crossref
Doaa M. Masoud, Rasha A. Azzam, Fatma Hamdy, Amal A.I. Mekawey & Hatem A. Abdel‐Aziz. (2019) Synthesis of some novel pyrazoline‐thiazole hybrids and their antimicrobial activities. Journal of Heterocyclic Chemistry 56:11, pages 3030-3041.
Crossref
Ranjit Singh & Ranju Bansal. (2019) 16,17-N′-(alky/arylsulfonyl)pyrazoline substituted neuroprotective heterosteroids: Synthesis, molecular docking and preclinical efficacy/toxicity studies in rodents. Steroids 148, pages 114-124.
Crossref
K. H. Ibnaouf, M. A. Ibrahem, O. Aldaghri, Raed Alhathlool & A. O. Elzupir. (2019) Structural, optical characteristics of 3-(p-N, N-dimethyl aminophenyl) 5-phenyl-1H-pyrazole: tuning band gaps with acid solutions. Journal of Materials Science: Materials in Electronics 30:15, pages 14312-14319.
Crossref
Ahmad M. Farag & Asmaa M. Fahim. (2019) Synthesis, biological evaluation and DFT calculation of novel pyrazole and pyrimidine derivatives. Journal of Molecular Structure 1179, pages 304-314.
Crossref
K. H. Ibnaouf, A. O. Elzupir, M. A. Ibrahem, M. K. M. Ali & Muhanna K. Al-Muhanna. (2018) Optical Characteristics and Structural Properties of 3-(p-Nitrophenyl)-5-phenyl-1H-pyrazole. Journal of Electronic Materials 48:2, pages 861-866.
Crossref
Yuan Chen, Hao Fan & Elena Galoppini. 2009. PATAI'S Chemistry of Functional Groups. PATAI'S Chemistry of Functional Groups 1 46 .
Jeong-Hwan Kim, Haruki Eguchi, Masanari Umemura & Yoshihiro Ishikawa. 2019. Materials for Biomedical Engineering. Materials for Biomedical Engineering 427 461 .
Ahmet Özdemir, Belgin Sever & Mehlika Dilek Altıntop. (2018) New Benzodioxole-based Pyrazoline Derivatives: Synthesis and Anticandidal, In silico ADME, Molecular Docking Studies. Letters in Drug Design & Discovery 16:1, pages 82-92.
Crossref
Ahmed A. Abd-Rabou, Bakr F. Abdel-Wahab & Mohamed S. Bekheit. (2018) Synthesis, molecular docking, and evaluation of novel bivalent pyrazolinyl-1,2,3-triazoles as potential VEGFR TK inhibitors and anti-cancer agents. Chemical Papers 72:9, pages 2225-2237.
Crossref
Ahmet Özdemir, Belgin Sever, Mehlika Altıntop, Elif Kaya Tilki & Miriş Dikmen. (2018) Design, Synthesis, and Neuroprotective Effects of a Series of Pyrazolines against 6-Hydroxydopamine-Induced Oxidative Stress. Molecules 23:9, pages 2151.
Crossref
Josiane Weber Tessmann, Julieti Buss, Karine Rech Begnini, Lucas Moraes Berneira, Favero Reisdorfer Paula, Claudio Martin Pereira de Pereira, Tiago Collares & Fabiana Kömmling Seixas. (2017) Antitumor potential of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-1H-pyrazoles in human bladder cancer cells. Biomedicine & Pharmacotherapy 94, pages 37-46.
Crossref
Hong Wang, Jinhong Zheng, Weijie Xu, Cheng Chen, Duncan Wei, Wenxiu Ni & Ying Pan. (2017) A New Series of Cytotoxic Pyrazoline Derivatives as Potential Anticancer Agents that Induce Cell Cycle Arrest and Apoptosis. Molecules 22:10, pages 1635.
Crossref
Edith Nagy & Salvatore D. Lepore. (2017) Alkyne Cycloadditions Mediated by Tetrabutylammonium Fluoride: A Unified and Diversifiable Route to Isoxazolines and Pyrazolines. Organic Letters 19:14, pages 3695-3698.
Crossref
Mikhail Yu. Ovchinnikov, Tagir A. Yangirov, Alexander N. Lobov, Rimma M. Sultanova & Sergey L. Khursan. (2017) Nature of Lewis Base Catalysis of 1,3-Dipolar Cycloaddition of Methyl Diazoacetate to Methyl Acrylate; NMR Kinetic Spectroscopy and DFT Study. The Journal of Physical Chemistry B 121:27, pages 6601-6609.
Crossref
Mohd. Imran Ansari & Suroor Ahmad Khan. (2017) Synthesis and antimicrobial activity of some novel quinoline-pyrazoline-based coumarinyl thiazole derivatives. Medicinal Chemistry Research 26:7, pages 1481-1496.
Crossref
Kamal M. Dawood, Salwa M. Moghazy & Ahmad M. Farag. (2017) Convenient synthesis of azolopyrimidine, azolotriazine, azinobenzimidazole and 1,3,4-thiadiazole derivatives. Arabian Journal of Chemistry 10, pages S2782-S2789.
Crossref
Kiran Gangarapu, Gouthami Thumma, Sarangapani Manda, Anvesh Jallapally, Ravi Jarapula & Sriram Rekulapally. (2017) Design, synthesis and molecular docking of novel structural hybrids of substituted isatin based pyrazoline and thiadiazoline as antitumor agents. Medicinal Chemistry Research 26:4, pages 819-829.
Crossref
Aftab Ahmad, Asif Husain, Shah Alam Khan, Mohd. Mujeeb & Anil Bhandari. (2016) Synthesis, antimicrobial and antitubercular activities of some novel pyrazoline derivatives. Journal of Saudi Chemical Society 20:5, pages 577-584.
Crossref
Alba Montoya, Jairo Quiroga, Rodrigo Abonia, Marcos Derita, Maximiliano Sortino, Alfredo Ornelas, Susana Zacchino & Braulio Insuasty. (2016) Hybrid Molecules Containing a 7-Chloro-4-aminoquinoline Nucleus and a Substituted 2-Pyrazoline with Antiproliferative and Antifungal Activity. Molecules 21:8, pages 969.
Crossref
Dmytro Havrylyuk, Olexandra Roman & Roman Lesyk. (2016) Synthetic approaches, structure activity relationship and biological applications for pharmacologically attractive pyrazole/pyrazoline–thiazolidine-based hybrids. European Journal of Medicinal Chemistry 113, pages 145-166.
Crossref
Waseem A. Wani, Umair Baig, Sheikh Shreaz, Rayees Ahmad Shiekh, Prince Firdous Iqbal, Ehtesham Jameel, Akil Ahmad, Siti Hamidah Mohd-Setapar, Md. Mushtaque & Lee Ting Hun. (2016) Recent advances in iron complexes as potential anticancer agents. New Journal of Chemistry 40:2, pages 1063-1090.
Crossref
Muhammed Karabacak, Mehlika Altıntop, Halil İbrahim Çiftçi, Ryoko Koga, Masami Otsuka, Mikako Fujita & Ahmet Özdemir. (2015) Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents. Molecules 20:10, pages 19066-19084.
Crossref
Mostafa E. Salem, Ashour A. Ahmed, Mohamed R. Shaaban, Mohamed F. Shibl & Ahmad M. Farag. (2015) Regioselective synthesis and ab initio calculations of fused heterocycles thermally and under microwave irradiation. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 148, pages 175-183.
Crossref
Gergő Mótyán, István Zupkó, Renáta Minorics, Gyula Schneider, János Wölfling & Éva Frank. (2015) Lewis acid-induced intramolecular access to novel steroidal ring D-condensed arylpyrazolines exerting in vitro cell-growth-inhibitory effects. Molecular Diversity 19:3, pages 511-527.
Crossref
Mehlika Dilek Altıntop, Ahmet Özdemir, Gülhan Turan-Zitouni, Sinem Ilgın, Özlem Atlı, Rasime Demirel & Zafer Asım Kaplancıklı. (2015) A novel series of thiazolyl–pyrazoline derivatives: Synthesis and evaluation of antifungal activity, cytotoxicity and genotoxicity. European Journal of Medicinal Chemistry 92, pages 342-352.
Crossref
Ahmet Özdemir, Mehlika Altıntop, Zafer Kaplancıklı, Özgür Can, Ümide Demir Özkay & Gülhan Turan-Zitouni. (2015) Synthesis and Evaluation of New 1,5-Diaryl-3-[4-(methyl-sulfonyl)phenyl]-4,5-dihydro-1H-pyrazole Derivatives as Potential Antidepressant Agents. Molecules 20:2, pages 2668-2684.
Crossref
Changjiang Yang, Juanjuan Li, Rong Zhou, Xiangyu Chen, Yunpeng Gao & Zhengjie He. (2015) Facile synthesis of spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines and their fungicidal activity. Organic & Biomolecular Chemistry 13:17, pages 4869-4878.
Crossref
Leonid I. Belen'kii & Yu B. Evdokimenkova. 2015. 193 363 .
Asghar Abbas, Safdar Hussain, Noureen Hafeez & Muhammad Moazzam Naseer. (2014) Synthesis and spectral characterization of new homologous 1,3,5-triaryl-2-pyrazolines: Influence of alkyloxy chain length on fluorescence. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 133, pages 182-189.
Crossref
B.S. Jayashree, Sukriti Nigam, Aravinda Pai & P.V.R. Chowdary. (2014) Overview on the recently developed coumarinyl heterocycles as useful therapeutic agents. Arabian Journal of Chemistry 7:6, pages 885-899.
Crossref
Dmytro Havrylyuk, Borys Zimenkovsky, Olexandr Karpenko, Philippe Grellier & Roman Lesyk. (2014) Synthesis of pyrazoline–thiazolidinone hybrids with trypanocidal activity. European Journal of Medicinal Chemistry 85, pages 245-254.
Crossref
Asghar Abbas, Safdar Hussain, Noureen Hafeez, Aurangzeb Hasan & Muhammad Moazzam Naseer. (2014) Synthesis and spectral characterization of new 1,3,5-triaryl-2-pyrazolines highlighting effect of alkyloxy chain length on fluorescence. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 127, pages 32-40.
Crossref
Pavel K. Mykhailiuk . (2014) Generation of C 2 F 5 CHN 2 In Situ and Its First Reaction: [3+2] Cycloaddition with Alkenes . Chemistry – A European Journal 20:17, pages 4942-4947.
Crossref
Evgeniy Y. Slobodyanyuk, Olexiy S. Artamonov, Oleg V. Shishkin & Pavel K. Mykhailiuk. (2014) One‐Pot Synthesis of CF 3 ‐Substituted Pyrazolines/Pyrazoles from Electron‐Deficient Alkenes/Alkynes and CF 3 CHN 2 Generated in situ: Optimized Synthesis of Tris(trifluoromethyl)pyrazole . European Journal of Organic Chemistry 2014:12, pages 2487-2495.
Crossref
Asghar Abbas, Habiba Nazir, Muhammad Moazzam Naseer, Michael Bolte, Safdar Hussain, Noureen Hafeez & Aurangzeb Hasan. (2014) Synthesis, spectral characterization, self-assembly and biological studies of N-acyl-2-pyrazolines bearing long alkoxy side chains. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 120, pages 176-184.
Crossref
Faiza Anam, Asghar Abbas, Kong Mun Lo, Zia-ur-Rehman Zia-ur-Rehman, Shahid Hameed & Muhammad Moazzam Naseer. (2014) Homologous 1,3,5-triarylpyrazolines: synthesis, CH⋯π interactions guided self-assembly and effect of alkyloxy chain length on DNA binding properties. New J. Chem. 38:11, pages 5617-5625.
Crossref
Dmytro Havrylyuk, Borys Zimenkovsky, Olexandr Vasylenko, Craig W. Day, Donald F. Smee, Philippe Grellier & Roman Lesyk. (2013) Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones. European Journal of Medicinal Chemistry 66, pages 228-237.
Crossref
Ahmed Mehanna. (2013) Antidiabetic agents: past, present and future. Future Medicinal Chemistry 5:4, pages 411-430.
Crossref
Mehlika D. Altintop, Ahmet Özdemir, Zafer A. Kaplancikli, Gülhan Turan-Zitouni, Halide E. Temel & Gülşen A. Çiftçi. (2013) Synthesis and Biological Evaluation of Some Pyrazoline Derivatives Bearing a Dithiocarbamate Moiety as New Cholinesterase Inhibitors. Archiv der Pharmazie 346:3, pages 189-199.
Crossref
Kishwar SaleemWaseem A Wani, Ashanul Haque, Mohamad Nadeem Lone, Ming-Fa Hsieh, Mohamad Aman Jairajpuri & Imran Ali. (2013) Synthesis, DNA binding, hemolysis assays and anticancer studies of copper(II), nickel(II) and iron(III) complexes of a pyrazoline-based ligand. Future Medicinal Chemistry 5:2, pages 135-146.
Crossref
Alexander Ciupa, Paul A. De Bank, Mary F. Mahon, Pauline J. Wood & Lorenzo Caggiano. (2013) Synthesis and antiproliferative activity of some 3-(pyrid-2-yl)-pyrazolines. MedChemComm 4:6, pages 956.
Crossref
Anand Singh, Amanda L. Loomer & Gregory P. Roth. (2012) Synthesis of Oxindolyl Pyrazolines and 3-Amino Oxindole Building Blocks via a Nitrile Imine [3 + 2] Cycloaddition Strategy . Organic Letters 14:20, pages 5266-5269.
Crossref
Imran Ali, Waseem A. Wani, Amber Khan, Ashanul Haque, Aijaz Ahmad, Kishwar Saleem & Nikhat Manzoor. (2012) Synthesis and synergistic antifungal activities of a pyrazoline based ligand and its copper(II) and nickel(II) complexes with conventional antifungals. Microbial Pathogenesis 53:2, pages 66-73.
Crossref

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