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The therapeutic potential of 5-HT1A receptors: a patent review

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Pages 887-902 | Published online: 13 Jul 2012

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Jakub Staroń, Ryszard Bugno, Adam S. Hogendorf & Andrzej J. Bojarski. (2018) 5-HT1A receptor ligands and their therapeutic applications: review of new patents. Expert Opinion on Therapeutic Patents 28:9, pages 679-689.
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O. A. Lyubashina, I. I. Busygina, S. S. Panteleev & A. D. Nozdrachev. (2017) Antinociceptive effect of the agonist of 5-HT1A receptors buspirone in the model of abdominal pain in dogs. Doklady Biological Sciences 473:1, pages 46-49.
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Liang Yang, Gang Song, Yinghui Ning & Chi-Sang Poon. (2015) A latent serotonin-1A receptor-gated spinal afferent pathway inhibiting breathing. Brain Structure and Function 221:8, pages 4159-4168.
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Valeria Pittalà, Maria A. Siracusa, Loredana Salerno, Giuseppe Romeo, Maria N. Modica, Nather Madjid & Sven Ove Ogren. (2015) Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands. European Neuropsychopharmacology 25:8, pages 1314-1323.
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Nikolas Stroth, Mauro Niso, Nicola A. Colabufo, Roberto Perrone, Per Svenningsson, Enza Lacivita & Marcello Leopoldo. (2015) Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2. Bioorganic & Medicinal Chemistry 23:15, pages 4824-4830.
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Yusuke Murata, Yuki Yanagihara, Masayoshi Mori, Kazunori Mine & Munechika Enjoji. (2015) Chronic treatment with tandospirone, a serotonin 1A receptor partial agonist, inhibits psychosocial stress-induced changes in hippocampal neurogenesis and behavior. Journal of Affective Disorders 180, pages 1-9.
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Ferdinando Fiorino, Beatrice Severino, Elisa Magli, Antonio Ciano, Giuseppe Caliendo, Vincenzo Santagada, Francesco Frecentese & Elisa Perissutti. (2013) 5-HT 1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer . Journal of Medicinal Chemistry 57:11, pages 4407-4426.
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Masayoshi Mori, Yusuke Murata, Asami Matsuo, Tomoyo Takemoto & Kazunori Mine. (2014) Chronic Treatment with the 5-HT1A Receptor Partial Agonist Tandospirone Increases Hippocampal Neurogenesis. Neurology and Therapy 3:1, pages 67-77.
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Lili Xu, Shanglin Zhou, Kunqian Yu, Bo Gao, Hualiang Jiang, Xuechu Zhen & Wei Fu. (2013) Molecular Modeling of the 3D Structure of 5-HT 1A R: Discovery of Novel 5-HT 1A R Agonists via Dynamic Pharmacophore-Based Virtual Screening . Journal of Chemical Information and Modeling 53:12, pages 3202-3211.
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