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Expert Opinion on Therapeutic Patents Volume 23, 2013 - Issue 1
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Reviews

Novel prostaglandin receptor modulators: a patent review (2002 – 2012) – part I: non-EP receptor modulators

Christina LamersGoethe University Frankfurt am Main, Frankfurt, [email protected]
,
Daniel FleschGoethe University Frankfurt am Main, Frankfurt, [email protected]
,
Manfred Schubert-ZsilaveczGoethe University Frankfurt am Main, Frankfurt, [email protected]
&
Daniel MerkGoethe University Frankfurt am Main, Frankfurt, [email protected]
Pages 47-77 | Published online: 14 Nov 2012

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Peter Norman. (2014) Update on the status of DP2 receptor antagonists; from proof of concept through clinical failures to promising new drugs. Expert Opinion on Investigational Drugs 23:1, pages 55-66.
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Luying Chen, Ge Yan & Tomohiko Ohwada. (2022) Building on endogenous lipid mediators to design synthetic receptor ligands. European Journal of Medicinal Chemistry 231, pages 114154.
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Ewgenij Proschak, Pascal Heitel, Lena Kalinowsky & Daniel Merk. (2017) Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery. Journal of Medicinal Chemistry 60:13, pages 5235-5266.
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Anna Cooper, Sameek Singh, Sarah Hook, Joel D. A. Tyndall & Andrea J. Vernall. (2017) Chemical Tools for Studying Lipid-Binding Class A G Protein–Coupled Receptors. Pharmacological Reviews 69:3, pages 316-353.
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Roopesh Singh Gangwar, Nadine Landolina, Ludovica Arpinati & Francesca Levi-Schaffer. (2017) Mast cell and eosinophil surface receptors as targets for anti-allergic therapy. Pharmacology & Therapeutics 170, pages 37-63.
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David A. Sykes, Michelle E. Bradley, Darren M. Riddy, Elizabeth Willard, John Reilly, Asadh Miah, Carsten Bauer, Simon J. Watson, David A. Sandham, Gerald Dubois & Steven J. Charlton. (2016) Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy. Molecular Pharmacology 89:5, pages 593-605.
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Daniel Merk, Martina Zettl, Dieter Steinhilber, Oliver Werz & Manfred Schubert-Zsilavecz. (2015) Pirinixic acids: flexible fatty acid mimetics with various biological activities. Future Medicinal Chemistry 7:12, pages 1597-1616.
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Michael G. Johnson, Jim (Jiwen) Liu, An-Rong Li, Bettina van Lengerich, Sophie Wang, Julio C. Medina, Tassie L. Collins, Jay Danao, Lisa Seitz, Angela Willee, Warren D’Souza, Alison L. Budelsky, Peter W. Fan & Simon G.W. Wong. (2014) Solving time-dependent CYP3A4 inhibition for a series of indole-phenylacetic acid dual antagonists of the PGD2 receptors CRTH2 and DP. Bioorganic & Medicinal Chemistry Letters 24:13, pages 2877-2880.
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Neelu Kaila, Bruce Follows, Louis Leung, Jennifer Thomason, Adrian Huang, Alessandro Moretto, Kristin Janz, Michael Lowe, Tarek S. Mansour, Cedric Hubeau, Karen Page, Paul Morgan, Susan Fish, Xin Xu, Cara Williams & Eddine Saiah. (2014) Discovery of Isoquinolinone Indole Acetic Acids as Antagonists of Chemoattractant Receptor Homologous Molecule Expressed on Th2 Cells (CRTH2) for the Treatment of Allergic Inflammatory Diseases. Journal of Medicinal Chemistry 57:4, pages 1299-1322.
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