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Danielle Borges Germano, Steffany Bernardo Oliveira, André Luis Lacerda Bachi, Yára Juliano, Neil Ferreira Novo, Jônatas Bussador do Amaral & Carolina Nunes França. (2023) Monocyte chemokine receptors as therapeutic targets in cardiovascular diseases. Immunology Letters 256-257, pages 1-8.
Crossref
Crossref
Hyun Sik Na, Seon-Yeong Lee, Dong Hwan Lee, Jin Seok Woo, Si-Young Choi, Keun-Hyung Cho, Seon Ae Kim, Eun Jeong Go, A Ram Lee, Jeong-Won Choi, Seok Jung Kim & Mi-La Cho. (2022) Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat model. Journal of Translational Medicine 20:1.
Crossref
Crossref
Ronghui Lin, Yong Gong & Rhys Salter. (2022)
Synthesis of deuterium‐labeled CCR2 antagonist JNJ‐26131300, [4‐(1
H
‐indol‐ 3‐yl)‐piperidin‐1‐yl]‐{1‐[3‐(3,4,5‐trifluoro‐phenyl)‐acryloyl]‐piperidin‐4‐yl}‐acetic acid
. Journal of Labelled Compounds and Radiopharmaceuticals 65:5, pages 147-151.
Crossref
Crossref
Robert J. Cherney, Prakash Anjanappa, Kumaravel Selvakumar, Douglas G. Batt, Gregory D. Brown, Anne V. Rose, Ragini Vuppugalla, Jing Chen, Jian Pang, Songmei Xu, Melissa Yarde, Andrew J. Tebben, Venkatram Reddy Paidi, Mary Ellen Cvijic, Arvind Mathur, Joel C. Barrish, Sandhya Mandlekar, Qihong Zhao & Percy H. Carter. (2021) BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate. ACS Medicinal Chemistry Letters 12:11, pages 1753-1758.
Crossref
Crossref
Michael G. Yang, Zili Xiao, Rulin Zhao, Andrew J. Tebben, Bei Wang, Robert J. Cherney, Douglas G. Batt, Gregory D. Brown, Mary Ellen Cvijic, John V. Duncia, Michael A. Gallela, Daniel S. Gardner, Purnima Khandelwal, Mary F. Malley, Jian Pang, Anne V. Rose, Joseph B. SantellaIIIIII, Amy A. Sarjeant, Songmei Xu, Arvind Mathur, Sandhya Mandlekar, Ragini Vuppugalla, Qihong Zhao & Percy H. Carter. (2021) Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2. ACS Medicinal Chemistry Letters 12:6, pages 969-975.
Crossref
Crossref
Hongwei Jin, Jie Xia, Zhenming Liu, Xiang Simon Wang & Liangren Zhang. (2021) A unique ligand‐steered strategy for CC chemokine receptor 2 homology modeling to facilitate structure‐based virtual screening. Chemical Biology & Drug Design 97:4, pages 944-961.
Crossref
Crossref
Natalia V. Ortiz Zacarías, Kirti K. Chahal, Tereza Šimková, Cas van der Horst, Yi Zheng, Asuka Inoue, Emy Theunissen, Lloyd Mallee, Daan van der Es, Julien Louvel, Adriaan P. IJzerman, Tracy M. Handel, Irina Kufareva & Laura H. Heitman. (2021) Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2. Journal of Medicinal Chemistry 64:5, pages 2608-2621.
Crossref
Crossref
Michael G. Yang, Zili Xiao, Robert J. Cherney, Andrew J. Tebben, Douglas G. Batt, Gregory D. Brown, Jing Chen, Mary Ellen Cvijic, Marta Dabros, John V. Duncia, Michael Galella, Daniel S. Gardner, Purnima Khandelwal, Soo S. Ko, Mary F. Malley, Ruowei Mo, Jian Pang, Anne V. Rose, Joseph B. SantellaIIIIII, Hong Shi, Anurag Srivastava, Sarah C. Traeger, Bei Wang, Songmei Xu, Rulin Zhao, Joel C. Barrish, Sandhya Mandlekar, Qihong Zhao & Percy H. Carter. (2019) Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672. ACS Medicinal Chemistry Letters 10:3, pages 300-305.
Crossref
Crossref
Anna-Katharina Apel, Robert K.Y. Cheng, Christofer S. Tautermann, Michael Brauchle, Chia-Ying Huang, Alexander Pautsch, Michael Hennig, Herbert Nar & Gisela Schnapp. (2019) Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists. Structure 27:3, pages 427-438.e5.
Crossref
Crossref
Li-Huai Qin, Zhi-Long Wang, Xin Xie & Ya-Qiu Long. (2018) Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrido[4,3-c]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategy. Bioorganic & Medicinal Chemistry 26:12, pages 3559-3572.
Crossref
Crossref
Natalia V. Ortiz Zacarías, Eelke B. Lenselink, Adriaan P. IJzerman, Tracy M. Handel & Laura H. Heitman. (2018) Intracellular Receptor Modulation: Novel Approach to Target GPCRs. Trends in Pharmacological Sciences 39:6, pages 547-559.
Crossref
Crossref
Ramesh N. Patel. (2018) Biocatalysis for synthesis of pharmaceuticals. Bioorganic & Medicinal Chemistry 26:7, pages 1252-1274.
Crossref
Crossref
Yongjian Liu, Sean P. Gunsten, Deborah H. Sultan, Hannah P. Luehmann, Yongfeng Zhao, T. Scott Blackwell, Zachary Bollermann-Nowlis, Jie-hong Pan, Derek E. Byers, Jeffrey J. Atkinson, Daniel Kreisel, Michael J. Holtzman, Robert J. Gropler, Christophe Combadiere & Steven L. Brody. (2017) PET-based Imaging of Chemokine Receptor 2 in Experimental and Disease-related Lung Inflammation. Radiology 283:3, pages 758-768.
Crossref
Crossref
Wanming Zhao, Xingyu Wang, Richard M. Ransohoff & Lan Zhou. (2016)
CCR2 deficiency does not provide sustained improvement of muscular dystrophy in
mdx
5cv
mice
. The FASEB Journal 31:1, pages 35-46.
Crossref
Crossref
Joerg Deerberg, Siva J. Prasad, Chris Sfouggatakis, Martin D. Eastgate, Yu Fan, Ramakrishnan Chidambaram, Praveen Sharma, Li Li, Richard Schild, Jale Müslehiddinoğlu, Hyei-Jha Chung, Simon Leung & Victor Rosso. (2016)
Stereoselective Bulk Synthesis of CCR2 Antagonist BMS-741672: Assembly of an All-
cis
(
S,R,R
)-1,2,4-Triaminocyclohexane (TACH) Core via Sequential Heterogeneous Asymmetric Hydrogenations
. Organic Process Research & Development 20:11, pages 1949-1966.
Crossref
Crossref
Ramesh N. Patel. 2016. Applied Biocatalysis: From Fundamental Science to Industrial Applications. Applied Biocatalysis: From Fundamental Science to Industrial Applications
367
403
.
Ramesh N. Patel. 2016. Green Biocatalysis. Green Biocatalysis
71
114
.
Gregory D. Brown, Qing Shi, George V. Delucca, Douglas G. Batt, Michael A. Galella, Mary-Ellen Cvijic, Rui-Qin Liu, Feng Qiu, Qihong Zhao, Joel C. Barrish & Percy H. Carter. (2016) Discovery and synthesis of cyclohexenyl derivatives as modulators of CC chemokine receptor 2 activity. Bioorganic & Medicinal Chemistry Letters 26:2, pages 662-666.
Crossref
Crossref
Ramesh N. Patel. 2016. Organic Synthesis Using Biocatalysis. Organic Synthesis Using Biocatalysis
339
411
.
Ann Kathrin Strunz, Annelien J.M. Zweemer, Christina Weiss, Dirk Schepmann, Anna Junker, Laura H. Heitman, Michael Koch & Bernhard Wünsch. (2015) Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2). Bioorganic & Medicinal Chemistry 23:14, pages 4034-4049.
Crossref
Crossref
Percy H. Carter, Gregory D. Brown, Robert J. Cherney, Douglas G. Batt, Jing Chen, Cheryl M. Clark, Mary Ellen Cvijic, John V. Duncia, Soo S. Ko, Sandhya Mandlekar, Ruowei Mo, David J. Nelson, Jian Pang, Anne V. Rose, Joseph B. SantellaIIIIII, Andrew J. Tebben, Sarah C. Traeger, Songmei Xu, Qihong Zhao & Joel C. Barrish. (2015) Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5. ACS Medicinal Chemistry Letters 6:4, pages 439-444.
Crossref
Crossref
J. G. Cumming, P. A. MacFaul & A. G. Leach. (2015) Novel N-thiazolyl piperazine-1-carboxamide CCR2 antagonists – investigation of an unexpected reaction with glutathione. MedChemComm 6:12, pages 2140-2145.
Crossref
Crossref
M. Vilums, A.J.M. Zweemer, S. Dekkers, Y. Askar, H. de Vries, J. Saunders, D. Stamos, J. Brussee, L.H. Heitman & A.P. IJzerman. (2014) Design and synthesis of novel small molecule CCR2 antagonists: Evaluation of 4-aminopiperidine derivatives. Bioorganic & Medicinal Chemistry Letters 24:23, pages 5377-5380.
Crossref
Crossref
Dionna W. WilliamsDesiree ByrdLeah H. RubinKathryn AnastosSusan MorgelloJoan W. Berman. (2014)
CCR2 on CD14
+
CD16
+
monocytes is a biomarker of HIV-associated neurocognitive disorders
. Neurology Neuroimmunology & Neuroinflammation 1:3.
Crossref
Crossref
Michael P. Winters, Christopher A. Teleha, Fu-An Kang, David McComsey, John C. O’Neill, Cuifen Hou, Thomas Kirchner, Ping Wang, Dana Johnson & Zhihua Sui. (2014) The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2. Bioorganic & Medicinal Chemistry Letters 24:9, pages 2137-2140.
Crossref
Crossref
Robert J. Cherney, Ruowei Mo, Michael G. Yang, Zili Xiao, Qihong Zhao, Sandhya Mandlekar, Mary Ellen Cvijic, Israel F. Charo, Joel C. Barrish, Carl P. Decicco & Percy H. Carter. (2014) Alkylsulfone-containing trisubstituted cyclohexanes as potent and bioavailable chemokine receptor 2 (CCR2) antagonists. Bioorganic & Medicinal Chemistry Letters 24:7, pages 1843-1845.
Crossref
Crossref
Adam A. Skelton, Yushir R. Maharaj & Mahmoud E. S. Soliman. (2013) Target-Bound Generated Pharmacophore Model to Improve the Pharmacophore-Based Virtual Screening: Identification of G-Protein Coupled Human CCR2 Receptors Inhibitors as Anti-Inflammatory Drugs. Cellular and Molecular Bioengineering 7:1, pages 45-57.
Crossref
Crossref