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Benzodiazepine receptor ligands: a patent review (2006 – 2012)

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Pages 843-866 | Published online: 24 Mar 2013

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Letizia Crocetti & Gabriella Guerrini. (2020) GABAA receptor subtype modulators in medicinal chemistry: an updated patent review (2014-present). Expert Opinion on Therapeutic Patents 30:6, pages 409-432.
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Marie-Christine Tonon, Hubert Vaudry, Julien Chuquet, Florent Guillebaud, Jinjiang Fan, Olfa Masmoudi-Kouki, David Vaudry, Damien Lanfray, Fabrice Morin, Vincent Prevot, Vassilios Papadopoulos, Jean-Denis Troadec & Jérôme Leprince. (2020) Endozepines and their receptors: Structure, functions and pathophysiological significance. Pharmacology & Therapeutics 208, pages 107386.
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A. I. Golovko, M. B. Ivanov, E. S. Golovko, V. B. Dolgo-Saburov & E. P. Zatsepin. (2018) The Neurochemical Mechanisms of the Pharmacological Activities of Inverse Agonists of the Benzodiazepine Binding Site. Neurochemical Journal 12:4, pages 337-346.
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Alshaimaa A. Elgarf, David C. B. Siebert, Friederike Steudle, Angelika Draxler, Guanguan Li, Shengming Huang, James M. Cook, Margot Ernst & Petra Scholze. (2018) Different Benzodiazepines Bind with Distinct Binding Modes to GABA A Receptors . ACS Chemical Biology 13:8, pages 2033-2039.
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Tamara Timić Stamenić, Michael M. Poe, Sabah Rehman, Anja Santrač, Branka Divović, Petra Scholze, Margot Ernst, James M. Cook & Miroslav M. Savić. (2016) Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit. European Journal of Pharmacology 791, pages 433-443.
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Tamara Timić Stamenić, Srdjan Joksimović, Poonam Biawat, Tamara Stanković, Bojan Marković, James M Cook & Miroslav M Savić. (2015) Negative modulation of α 5 GABA A receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotion . Journal of Psychopharmacology 29:9, pages 1013-1024.
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Jeannette Y. Wick. (2013) The History of Benzodiazepines. The Consultant Pharmacist 28:9, pages 538-548.
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