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Patent Evaluations

Evaluation of WO2013136076: two crystalline forms of the phosphatidylinositol 3-kinase-δ inhibitor RV-1729

, MBA PhD

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Paul Glossop, Gavin Whitlock & Karl Gibson. (2015) Small-molecule anti-inflammatory drug compositions for the treatment of asthma: a patent review (2013 – 2014). Expert Opinion on Therapeutic Patents 25:7, pages 743-754.
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Peter Norman. (2014) Evaluation of WO2014075392 and WO2014075393, Merck’s first PI3Kδ inhibitor filings. Expert Opinion on Therapeutic Patents 24:11, pages 1277-1282.
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Articles from other publishers (8)

Jun Wei, Dongyan Gu, Leer Yuan & Rong Sheng. (2023) Advances in the Discovery of Novel Inhaled PI3Kδ Inhibitors for the Treatment of Asthma. Current Medicinal Chemistry 30:17, pages 1971-1992.
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Akira Yamasaki, Ryota Okazaki & Tomoya Harada. (2022) Neutrophils and Asthma. Diagnostics 12:5, pages 1175.
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Chiara Tarantelli, Lisa Argnani, Pier Luigi Zinzani & Francesco Bertoni. (2021) PI3Kδ Inhibitors as Immunomodulatory Agents for the Treatment of Lymphoma Patients. Cancers 13:21, pages 5535.
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Sharif Moradi, Esmaeil Jarrahi, Ali Ahmadi, Jafar Salimian, Mehrdad Karimi, Azadeh Zarei, Sadegh Azimzadeh Jamalkandi & Mostafa Ghanei. (2021) PI3K signalling in chronic obstructive pulmonary disease and opportunities for therapy . The Journal of Pathology 254:5, pages 505-518.
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Flora Pirozzi, Kai Ren, Alessandra Murabito & Alessandra Ghigo. (2019) PI3K Signaling in Chronic Obstructive Pulmonary Disease: Mechanisms, Targets, and Therapy. Current Medicinal Chemistry 26:16, pages 2791-2800.
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Matthew W. D. Perry, Raolat Abdulai, Mickael Mogemark, Jens Petersen, Matthew J. Thomas, Barbara Valastro & Annika Westin Eriksson. (2018) Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases. Journal of Medicinal Chemistry 62:10, pages 4783-4814.
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Manman Wei, Xi Zhang, Xiang Wang, Zilan Song, Jian Ding, Ling-Hua Meng & Ao Zhang. (2017) SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-kinase delta (PI3Kδ) inhibitors. European Journal of Medicinal Chemistry 125, pages 1156-1171.
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Manman Wei, Xiang Wang, Zilan Song, Mingkun Jiao, Jian Ding, Ling-Hua Meng & Ao Zhang. (2015) Targeting PI3Kδ: Emerging Therapy for Chronic Lymphocytic Leukemia and Beyond. Medicinal Research Reviews 35:4, pages 720-752.
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