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Patent Evaluations

Novel picolinamide-based cystic fibrosis transmembrane regulator modulators: evaluation of WO2013038373, WO2013038376, WO2013038381, WO2013038386 and WO2013038390

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Pedro Mondejar-Lopez, Maria Dolores Pastor-Vivero, Manuel Sanchez-Solis & Amparo Escribano. (2017) Cystic fibrosis treatment: targeting the basic defect. Expert Opinion on Orphan Drugs 5:2, pages 181-192.
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Lindsay J. Caverly, Sebastián A. Riquelme & Katherine B. Hisert. (2022) The Impact of Highly Effective Modulator Therapy on Cystic Fibrosis Microbiology and Inflammation. Clinics in Chest Medicine 43:4, pages 647-665.
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Svetlana A. Smirnikhina, Ekaterina V. Kondrateva, Elmira P. Adilgereeva, Arina A. Anuchina, Milyausha I. Zaynitdinova, Yana S. Slesarenko, Angelina S. Ershova, Kirill D. Ustinov, Matvei I. Yasinovsky, Elena L. Amelina, Ekaterina S. Voronina, Valentina D. Yakushina, Vyacheslav Yu. Tabakov & Alexander V. Lavrov. (2020) P.F508del editing in cells from cystic fibrosis patients. PLOS ONE 15:11, pages e0242094.
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Martina Gentzsch & Marcus A. Mall. (2018) Ion Channel Modulators in Cystic Fibrosis. Chest 154:2, pages 383-393.
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Phil R. Kym, Xueqing Wang, Mathieu Pizzonero & Steven E. Van der Plas. 2018. 235 276 .
Mark P. Murphy & Emma Caraher. (2016) Current and Emerging Therapies for the Treatment of Cystic Fibrosis or Mitigation of Its Symptoms. Drugs in R&D 16:1, pages 1-17.
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Gerhard Laus, Volker Kahlenberg, Sven Nerdinger, Frank Richter & Herwig Schottenberger. (2016) tert -Butyl 3-(3-methyl-1-oxidopyridin-1-ium-2-yl)benzoate . IUCrData 1:1.
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Ellen M. McDonagh, John P. Clancy, Russ B. Altman & Teri E. Klein. (2015) PharmGKB summary. Pharmacogenetics and Genomics 25:3, pages 149-156.
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