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Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature

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Feng Wang, Xin-Yu Cao, Guo-Qiang Lin, Ping Tian & Dingding Gao. (2022) Novel inhibitors of the STAT3 signaling pathway: an updated patent review (2014-present). Expert Opinion on Therapeutic Patents 32:6, pages 667-688.
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Nicole L. Blanchette, David H. Manz, Frank M. Torti & Suzy V. Torti. (2016) Modulation of hepcidin to treat iron deregulation: potential clinical applications. Expert Review of Hematology 9:2, pages 169-186.
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Ping-Shan Lai, David A Rosa, Ahmed Magdy Ali, Rodolfo F Gómez-Biagi, Daniel P Ball, Andrew E Shouksmith & Patrick T Gunning. (2015) A STAT inhibitor patent review: progress since 2011. Expert Opinion on Therapeutic Patents 25:12, pages 1397-1421.
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Articles from other publishers (15)

Qun Lai, Wenqiang Li, Hongping Wang, Siran Xu & Zhiping Deng. (2022) Emerging role of circRNAs in cancer under hypoxia (Review). Oncology Letters 24:4.
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Xin Chen, Can Luo, Yuting Bai, Lihua Yao, Qiyue Shanzhou, Yulei Xie, Shan Wang, Lei Xu, Xiaolan Guo, Xiaowu Zhong & Qing Wu. (2022) Analysis of Hypoxia Inducible Factor-1α Expression and Its Effects on Glycolysis of Esophageal Carcinoma. Critical Reviews in Eukaryotic Gene Expression 32:7, pages 47-66.
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Samantha J. Paddock, Samantha K. Swift, Victor Alencar-Almeida, Aria Kenarsary, Santiago Alvarez-Argote, Michael A. Flinn, Michaela Patterson & Caitlin C. O'Meara. (2021) IL4Rα signaling promotes neonatal cardiac regeneration and cardiomyocyte cell cycle activity. Journal of Molecular and Cellular Cardiology 161, pages 62-74.
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Marwa Ali A. Fathi, Amer Ali Abd El-Hafeez, Dalia Abdelhamid, Samar H. Abbas, Monica M. Montano & Mohamed Abdel-Aziz. (2019) 1,3,4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities. Bioorganic Chemistry 84, pages 150-163.
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Yang Yang & Zhi Shi. 2019. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy. Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy 53 65 .
Jacopo Sgrignani, Maura Garofalo, Milos Matkovic, Jessica Merulla, Carlo V. Catapano & Andrea Cavalli. (2018) Structural Biology of STAT3 and Its Implications for Anticancer Therapies Development. International Journal of Molecular Sciences 19:6, pages 1591.
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Je Won Park, Sang-Jip Nam & Yeo Joon Yoon. (2017) Enabling techniques in the search for new antibiotics: Combinatorial biosynthesis of sugar-containing antibiotics. Biochemical Pharmacology 134, pages 56-73.
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Daniel Vyoral & Jiri Petrak. (2017) Therapeutic potential of hepcidin − the master regulator of iron metabolism. Pharmacological Research 115, pages 242-254.
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Carolyn C. Arpin, Stephen Mac, Yanlin Jiang, Huiwen Cheng, Michelle Grimard, Brent D.G. Page, Malgorzata M. Kamocka, Sina Haftchenary, Han Su, Daniel P. Ball, David A. Rosa, Ping-Shan Lai, Rodolfo F. Gómez-Biagi, Ahmed M. Ali, Rahul Rana, Helmut Hanenberg, Kagan Kerman, Kyle C. McElyea, George E. Sandusky, Patrick T. Gunning & Melissa L. Fishel. (2016) Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics. Molecular Cancer Therapeutics 15:5, pages 794-805.
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Daniel P. Ball, Andrew M. Lewis, Declan Williams, Diana Resetca, Derek J. Wilson & Patrick T. Gunning. (2016) Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent. Oncotarget 7:15, pages 20669-20679.
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Kuppusamy Balamurugan. (2016) HIF-1 at the crossroads of hypoxia, inflammation, and cancer. International Journal of Cancer 138:5, pages 1058-1066.
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Jacopo Sgrignani, Simon Olsson, Dariusz Ekonomiuk, Davide Genini, Rolf Krause, Carlo V. Catapano & Andrea Cavalli. (2015) Molecular Determinants for Unphosphorylated STAT3 Dimerization Determined by Integrative Modeling. Biochemistry 54:35, pages 5489-5501.
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Mu-xing Li, Xin-yu Bi, Zhen Huang, Jian-jun Zhao, Yue Han, Zhi-yu Li, Ye-fan Zhang, Yuan Li, Xiao Chen, Xu-hui Hu, Hong Zhao & Jian-qiang Cai. (2015) Prognostic Role of Phospho-STAT3 in Patients with Cancers of the Digestive System: A Systematic Review and Meta-Analysis. PLOS ONE 10:5, pages e0127356.
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Mellissa J. Hicks, Qiuping Hu, Erin Macrae & James DeWille. (2015) Mitogen-activated protein kinase signaling controls basal and oncostatin M-mediated JUNB gene expression. Molecular and Cellular Biochemistry 403:1-2, pages 115-124.
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Peng Teng, Xiaolei Zhang, Haifan Wu, Qiao Qiao, Said M. Sebti & Jianfeng Cai. (2014) Identification of novel inhibitors that disrupt STAT3?DNA interaction from a ?-AApeptide OBOC combinatorial library. Chem. Commun. 50:63, pages 8739-8742.
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