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Patent Review

Small molecule glucagon receptor antagonists: a patent review (2011 – 2014)

(Principal Scientist)

Keep up to date with the latest research on this topic with citation updates for this article.

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Chen Cheng, Salman Jabri, Brandon M Taoka & Christopher J Sinz. (2020) Small molecule glucagon receptor antagonists: an updated patent review (2015–2019). Expert Opinion on Therapeutic Patents 30:7, pages 509-526.
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André J. Scheen, Nicolas Paquot & Pierre J. Lefèbvre. (2017) Investigational glucagon receptor antagonists in Phase I and II clinical trials for diabetes. Expert Opinion on Investigational Drugs 26:12, pages 1373-1389.
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Articles from other publishers (7)

Parimal Misra & Ranjan Chakrabarti. 2021. Drug Discovery and Drug Development. Drug Discovery and Drug Development 165 177 .
Nagaraju Kerru, Ashona Singh-Pillay, Paul Awolade & Parvesh Singh. (2018) Current anti-diabetic agents and their molecular targets: A review. European Journal of Medicinal Chemistry 152, pages 436-488.
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Shuangjie Shu, Antao Dai, Jiang Wang, Bin Wang, Yang Feng, Jia Li, Xiaoqing Cai, Dehua Yang, Dakota Ma, Ming-Wei Wang & Hong Liu. (2018) A novel series of 4-methyl substituted pyrazole derivatives as potent glucagon receptor antagonists: Design, synthesis and evaluation of biological activities. Bioorganic & Medicinal Chemistry 26:8, pages 1896-1908.
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Lise Bankir, Antonio Barbato, Ornella Russo, Gilles Crambert, Roberto Iacone, Nadine Bouby, Ludovica Perna & Pasquale Strazzullo. (2018) Renal potassium handling in carriers of the Gly40Ser mutation of the glucagon receptor suggests a role for glucagon in potassium homeostasis. Physiological Reports 6:8, pages e13661.
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Lise Bankir, Nadine Bouby, Bertrand Blondeau & Gilles Crambert. (2016) Glucagon actions on the kidney revisited: possible role in potassium homeostasis. American Journal of Physiology-Renal Physiology 311:2, pages F469-F486.
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Shuangjie Shu, Xiaoqing Cai, Jia Li, Yang Feng, Antao Dai, Jiang Wang, Dehua Yang, Ming-Wei Wang & Hong Liu. (2016) Design, synthesis, structure–activity relationships, and docking studies of pyrazole-containing derivatives as a novel series of potent glucagon receptor antagonists. Bioorganic & Medicinal Chemistry 24:12, pages 2852-2863.
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Clifford J Bailey, Abd A Tahrani & Anthony H Barnett. (2016) Future glucose-lowering drugs for type 2 diabetes. The Lancet Diabetes & Endocrinology 4:4, pages 350-359.
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