733
Views
21
CrossRef citations to date
0
Altmetric
Review

Farnesoid X receptor modulators (2011 – 2014): a patent review

, , &

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Stefano Fiorucci, Michele Biagioli, Monia Baldoni, Patrizia Ricci, Valentina Sepe, Angela Zampella & Eleonora Distrutti. (2021) The identification of farnesoid X receptor modulators as treatment options for nonalcoholic fatty liver disease. Expert Opinion on Drug Discovery 16:10, pages 1193-1208.
Read now
Hong Wang, Qingxian He, Guangji Wang, Xiaowei Xu & Haiping Hao. (2018) FXR modulators for enterohepatic and metabolic diseases. Expert Opinion on Therapeutic Patents 28:11, pages 765-782.
Read now
Valentina Sepe, Eleonora Distrutti, Stefano Fiorucci & Angela Zampella. (2018) Farnesoid X receptor modulators 2014-present: a patent review. Expert Opinion on Therapeutic Patents 28:5, pages 351-364.
Read now

Articles from other publishers (18)

Xiaoyue Li, Haoming Li, Kangyuan Qu, Yucheng Liu, Shuyan Chi, Qihui Yang, Beiping Tan, Shuang Zhang & Shiwei Xie. (2023) Dietary bile acids promote sterol metabolism, bile acids enterohepatic circulation, and apoptosis in juvenile Pacific white shrimp (Litopenaeus vannamei). Animal Feed Science and Technology 303, pages 115710.
Crossref
Qiang Ren, Ya Chen, Zongtao Zhou, Zongyu Cai, Shixuan Jiao, Wanqiu Huang, Bin Wang, Siliang Chen, Wenxin Wang, Zhijun Cao, Zhongcheng Yang, Liming Deng, Lijun Hu, Luyong Zhang & Zheng Li. (2023) Discovery of the First-in-Class Intestinal Restricted FXR and FABP1 Dual Modulator ZLY28 for the Treatment of Nonalcoholic Fatty Liver Disease. Journal of Medicinal Chemistry 66:9, pages 6082-6104.
Crossref
Shibin Yao, Shengjie Ren, Chunfang Cai, Xiamin Cao, Ye Shi, Ping Wu & Yuantu Ye. (2022) Glycocholic acid supplementation improved growth performance and alleviated tissue damage in the liver and intestine in Pelteobagrus fulvidraco fed a high-pectin diet. Fish Physiology and Biochemistry.
Crossref
Stefano Fiorucci, Angela Zampella, Patrizia Ricci, Eleonora Distrutti & Michele Biagioli. (2022) Immunomodulatory functions of FXR. Molecular and Cellular Endocrinology 551, pages 111650.
Crossref
Michele Biagioli & Stefano Fiorucci. (2021) Bile acid activated receptors: Integrating immune and metabolic regulation in non-alcoholic fatty liver disease. Liver Research 5:3, pages 119-141.
Crossref
Anita Kumari, Lovika Mittal, Mitul Srivastava, Dharam Pal Pathak & Shailendra Asthana. (2021) Conformational Characterization of the Co-Activator Binding Site Revealed the Mechanism to Achieve the Bioactive State of FXR. Frontiers in Molecular Biosciences 8.
Crossref
John Rothman. 2021. Autism Spectrum Disorder - Profile, Heterogeneity, Neurobiology and Intervention. Autism Spectrum Disorder - Profile, Heterogeneity, Neurobiology and Intervention.
Marianna Potenza, Maria Maddalena Cavalluzzi, Gualtiero Milani, Gianluigi Lauro, Adriana Carino, Rosalinda Roselli, Stefano Fiorucci, Angela Zampella, Ciro Leonardo Pierri, Giovanni Lentini & Giuseppe Bifulco. (2021) Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR). Bioorganic Chemistry 111, pages 104897.
Crossref
Stefano Fiorucci, Eleonora Distrutti, Adriana Carino, Angela Zampella & Michele Biagioli. (2021) Bile acids and their receptors in metabolic disorders. Progress in Lipid Research 82, pages 101094.
Crossref
Dong Xiang, Jinyu Yang, Yanan Liu, Wenxi He, Si Zhang, Xiping Li, Chenliang Zhang & Dong Liu. (2019) Calculus Bovis Sativus Improves Bile Acid Homeostasis via Farnesoid X Receptor-Mediated Signaling in Rats With Estrogen-Induced Cholestasis. Frontiers in Pharmacology 10.
Crossref
Simona De Marino, Carmen Festa, Valentina Sepe & Angela Zampella. 2019. Bile Acids and Their Receptors. Bile Acids and Their Receptors 137 165 .
Karolina E. Zaborska & Bethany P. Cummings. (2018) Rethinking Bile Acid Metabolism and Signaling for Type 2 Diabetes Treatment. Current Diabetes Reports 18:11.
Crossref
Peter HegyiJozsef MaléthJulian R. WaltersAlan F. HofmannStephen J. Keely. (2018) Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease. Physiological Reviews 98:4, pages 1983-2023.
Crossref
Fan Yang, Yao Wang, Gang Li, Juan Xue, Zhi-Lin Chen, Feng Jin, Lei Luo, Xuan Zhou, Qian Ma, Xin Cai, Hua-Rong Li & Lei Zhao. (2018) Effects of corilagin on alleviating cholestasis via farnesoid X receptor-associated pathways in vitro and in vivo . British Journal of Pharmacology 175:5, pages 810-829.
Crossref
Kim Frisch & Aage Kristian Olsen Alstrup. (2018) On the Evolution of Bile Salts and the Farnesoid X Receptor in Vertebrates. Physiological and Biochemical Zoology 91:2, pages 797-813.
Crossref
Andrea Ferrigno, Laura Giuseppina Di Pasqua, Clarissa Berardo, Veronica Siciliano, Vittoria Rizzo, Luciano Adorini, Plinio Richelmi & Mariapia Vairetti. (2018) The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury. PLOS ONE 13:1, pages e0191430.
Crossref
Edithe Selwa, Eddy Elisée, Agustin Zavala & Bogdan I. Iorga. (2017) Blinded evaluation of farnesoid X receptor (FXR) ligands binding using molecular docking and free energy calculations. Journal of Computer-Aided Molecular Design 32:1, pages 273-286.
Crossref
Carmen Festa, Simona De Marino, Adriana Carino, Valentina Sepe, Silvia Marchianò, Sabrina Cipriani, Francesco S. Di Leva, Vittorio Limongelli, Maria C. Monti, Angela Capolupo, Eleonora Distrutti, Stefano Fiorucci & Angela Zampella. (2017) Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases. Frontiers in Pharmacology 8.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.