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Expert Opinion on Therapeutic Patents Volume 25, 2015 - Issue 10
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Review

A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents

Mayank Kumar SharmaThe M. S. University of Baroda, Pharmacy Department, Faculty of Technology and Engineering, KalabhavanVadodara – 390 001, [email protected]
,
Prashant R MurumkarThe M. S. University of Baroda, Pharmacy Department, Faculty of Technology and Engineering, KalabhavanVadodara – 390 001, [email protected]
,
Mahesh A BarmadeThe M. S. University of Baroda, Pharmacy Department, Faculty of Technology and Engineering, KalabhavanVadodara – 390 001, [email protected]
,
Rajani GiridharThe M. S. University of Baroda, Pharmacy Department, Faculty of Technology and Engineering, KalabhavanVadodara – 390 001, [email protected]
&
Mange Ram YadavThe M. S. University of Baroda, Pharmacy Department, Faculty of Technology and Engineering, KalabhavanVadodara – 390 001, [email protected]
Pages 1093-1116 | Published online: 10 Jul 2015

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George Amato, Nayaab S Khan & Rangan Maitra. (2019) A patent update on cannabinoid receptor 1 antagonists (2015-2018). Expert Opinion on Therapeutic Patents 29:4, pages 261-269.
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Articles from other publishers (24)

Thomas Högberg, Jean-Marie Receveur, Anthony Murray, Jean-Michel Linget, Pia K. Nørregaard, Paul B. Little & Martin Cooper. (2024) Optimizing and characterizing 4-methyl substituted pyrazol-3-carboxamides leading to the peripheral cannabinoid 1 receptor inverse agonist TM38837. Bioorganic & Medicinal Chemistry Letters 98, pages 129572.
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Raj Kamal Srivastava, Inigo Ruiz de Azua, Andrea Conrad, Martin Purrio & Beat Lutz. (2022) Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity. International Journal of Molecular Sciences 23:20, pages 12635.
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Thuy Nguyen, Thomas F. Gamage, David B. Finlay, Ann M. Decker, Tiffany L. Langston, Daniel Barrus, Michelle Glass, Jun-Xu Li, Terry P. Kenakin & Yanan Zhang. (2021) Development of 3-(4-Chlorophenyl)-1-(phenethyl)urea Analogues as Allosteric Modulators of the Cannabinoid Type-1 Receptor: RTICBM-189 is Brain Penetrant and Attenuates Reinstatement of Cocaine-Seeking Behavior. Journal of Medicinal Chemistry 65:1, pages 257-270.
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Iona J. MacDonald & Yi-Hung Chen. (2021) The Endocannabinoid System Contributes to Electroacupuncture Analgesia. Frontiers in Neuroscience 14.
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Paula Morales & Patricia H. Reggio. 2021. Cannabinoids and Neuropsychiatric Disorders. Cannabinoids and Neuropsychiatric Disorders 47 65 .
Robert Ettaro, Lucas Laudermilk, Stewart D. Clark & Rangan Maitra. (2020) Behavioral assessment of rimonabant under acute and chronic conditions. Behavioural Brain Research 390, pages 112697.
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Juan A. Páez & Nuria E. Campillo. (2019) Innovative Therapeutic Potential of Cannabinoid Receptors as Targets in Alzheimer’s Disease and Less Well-Known Diseases. Current Medicinal Chemistry 26:18, pages 3300-3340.
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George Amato, Robert Wiethe, Amruta Manke, Vineetha Vasukuttan, Rodney Snyder, Scott Runyon & Rangan Maitra. (2019) Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor – SAR efforts towards selectivity and peripheralization. Bioorganic & Medicinal Chemistry 27:16, pages 3632-3649.
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George Amato, Amruta Manke, Robert Wiethe, Vineetha Vasukuttan, Rodney Snyder, Yun Lan Yueh, Ann Decker, Scott Runyon & Rangan Maitra. (2019) Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor. Journal of Medicinal Chemistry 62:13, pages 6330-6345.
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Mesfin YimamPing JiaoMei HongLidia BrownellYoung-Chul LeeHyun-Jin KimJeong-Bum NamMi-Ran KimQi Jia. (2019) Morus alba , a Medicinal Plant for Appetite Suppression and Weight Loss . Journal of Medicinal Food 22:7, pages 741-751.
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David R. Janero, V. Kiran Vemuri & Alexandros Makriyannis. 2019. Cannabis Use Disorders. Cannabis Use Disorders 43 54 .
Thomas Rossolini, Jamie A. Leitch, Rachel Grainger & Darren J. Dixon. (2018) Photocatalytic Three-Component Umpolung Synthesis of 1,3-Diamines. Organic Letters 20:21, pages 6794-6798.
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Jorge Manzanares, David Cabañero, Nagore Puente, María S. García-Gutiérrez, Pedro Grandes & Rafael Maldonado. (2018) Role of the endocannabinoid system in drug addiction. Biochemical Pharmacology 157, pages 108-121.
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Mange Ram Yadav & Prashant R Murumkar. (2018) Advances in patented CB1 receptor antagonists for obesity. Pharmaceutical Patent Analyst 7:5, pages 169-173.
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George S. Amato, Amruta Manke, Vineetha Vasukuttan, Robert W. Wiethe, Rodney W. Snyder, Scott P. Runyon & Rangan Maitra. (2018) Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists. Bioorganic & Medicinal Chemistry 26:15, pages 4518-4531.
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Mayank Kumar Sharma, Jatin Machhi, Prashant Murumkar & Mange Ram Yadav. (2018) New role of phenothiazine derivatives as peripherally acting CB1 receptor antagonizing anti-obesity agents. Scientific Reports 8:1.
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Mahesh A. Barmade,Mayank K. Sharma. 2018. Vicinal Diaryl Substituted Heterocycles. Vicinal Diaryl Substituted Heterocycles 363 399 .
Atul N. Khadse & Mahesh A. Barmade. 2018. Vicinal Diaryl Substituted Heterocycles. Vicinal Diaryl Substituted Heterocycles 327 362 .
Prashant R. Murumkar & Rupesh V. Chikhale. 2018. Vicinal Diaryl Substituted Heterocycles. Vicinal Diaryl Substituted Heterocycles 191 219 .
Lizi Xia, Henk de Vries, Eelke B. Lenselink, Julien Louvel, Michael J. Waring, Leifeng Cheng, Sara Pahlén, Maria J. Petersson, Peter Schell, Roine I. Olsson, Laura H. Heitman, Robert J. Sheppard & Adriaan P. IJzerman. (2017) Structure–Affinity Relationships and Structure–Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists. Journal of Medicinal Chemistry 60:23, pages 9545-9564.
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Isvett Josefina Flores-Sanchez & Ana Carmela Ramos-Valdivia. (2016) A review from patents inspired by the genus Cannabis. Phytochemistry Reviews 16:4, pages 639-675.
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Emily E Thompson, Julia E Jagielo-Miller, V Kiran Vemuri, Alexandros Makriyannis & Peter J McLaughlin. (2016) CB1 antagonism produces behaviors more consistent with satiety than reduced reward value in food-maintained responding in rats. Journal of Psychopharmacology 30:5, pages 482-491.
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Patrice D. Cani, Hubert Plovier, Matthias Van Hul, Lucie Geurts, Nathalie M. Delzenne, Céline Druart & Amandine Everard. (2015) Endocannabinoids — at the crossroads between the gut microbiota and host metabolism. Nature Reviews Endocrinology 12:3, pages 133-143.
Crossref
Mayank Kumar Sharma, Prashant R. Murumkar, Guanglin Kuang, Yun Tang & Mange Ram Yadav. (2016) Identifying the structural features and diversifying the chemical domain of peripherally acting CB1 receptor antagonists using molecular modeling techniques. RSC Advances 6:2, pages 1466-1483.
Crossref

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