Citations (43)
Keep up to date with the latest research on this topic with citation updates for this article.
Articles from other publishers (43)
Ning-Bo Yi, Xing-Jie Hu, Fei Wang, Si-Yi Chen, Xiao-Xue Xu, Xin Li, Hao Wang, Taolei Sun, Zeng-Ying Qiao & Dong-Bing Cheng. (2023) Endogenous formaldehyde responsive fluorescent probe for bioimaging. Nano Research.
Crossref
Crossref
Yi Jun Desmond Tan, Danielle L Brooks, Kelly Yin Han Wong, Yuefei Huang, Jose R Romero, Jonathan S Williams & Luminita H Pojoga. (2023) Lysine-specific demethylase 1 deficiency modifies aldosterone synthesis in a sex-specific manner. Journal of Endocrinology 256:1.
Crossref
Crossref
Xin He, Baojing Zhang, Peng Cao, Honglei Wang, Shan Wu, Gang Wang, Fangyu Yang, Aijing Leng, Guobiao Liang & Dawei Li. (2022) Biotransformation of dihydrocapsaicin by human intestinal fungi and the inhibitory effects of metabolites against LSD1. Heliyon 8:12, pages e12325.
Crossref
Crossref
Rangan Mitra & Senthil Raja Ayyannan. (2022) Role of Lysine-specific Demethylase 1 and Its Small Molecule Inhibitors in Glioblastoma
Multiforme Therapy. Anti-Cancer Agents in Medicinal Chemistry 22:18, pages 3062-3085.
Crossref
Crossref
Jianshu Dong, Waqar Pervaiz, Bilal Tayyab, Dié Li, Lei Kang, Huimin Zhang, Huimin Gong, Xinli Ma, Jian Li, Clement Agboyibor, Yuefeng Bi & Hongmin Liu. (2022) A comprehensive comparative study on LSD1 in different cancers and tumor specific LSD1 inhibitors. European Journal of Medicinal Chemistry 240, pages 114564.
Crossref
Crossref
Rahul D. Jawarkar, Ravindra L. Bakal, Nobendu Mukherjee, Arabinda Ghosh, Magdi E. A. Zaki, Sami A. AL-Hussain, Aamal A. Al-Mutairi, Abdul Samad, Ajaykumar Gandhi & Vijay H. Masand. (2022) QSAR Evaluations to Unravel the Structural Features in Lysine-Specific Histone Demethylase 1A Inhibitors for Novel Anticancer Lead Development Supported by Molecular Docking, MD Simulation and MMGBSA. Molecules 27:15, pages 4758.
Crossref
Crossref
Martina Menna, Francesco Fiorentino, Biagina Marrocco, Alessia Lucidi, Stefano Tomassi, Domenica Cilli, Mauro Romanenghi, Matteo Cassandri, Silvia Pomella, Michele Pezzella, Donatella Del Bufalo, Mohammad Salik Zeya Ansari, Nevena Tomašević, Milan Mladenović, Monica Viviano, Gianluca Sbardella, Rossella Rota, Daniela Trisciuoglio, Saverio Minucci, Andrea Mattevi, Dante Rotili & Antonello Mai. (2022) Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. European Journal of Medicinal Chemistry 237, pages 114410.
Crossref
Crossref
Wasita W Parksook, Mahyar Heydarpour, Shadi K Gholami, James M Luther, Paul N Hopkins, Luminita H Pojoga & Jonathan S Williams. (2022) Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age. The Journal of Clinical Endocrinology & Metabolism 107:5, pages 1294-1302.
Crossref
Crossref
Zhong-Rui LI, Meng-Zhen GU, Xiao XU, Jing-Han ZHANG, Hai-Li ZHANG & Chao HAN. (2022) Promising natural lysine specific demethylase 1 inhibitors for cancer treatment: advances and outlooks. Chinese Journal of Natural Medicines 20:4, pages 241-257.
Crossref
Crossref
Xingrui He, Hang Zhang, Yingqian Zhang, Yang Ye, Shuo Wang, Renren Bai, Tian Xie & Xiang-Yang Ye. (2022) Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present). European Journal of Medicinal Chemistry 231, pages 114143.
Crossref
Crossref
Chao Yang, Yuan Fang, Xiang Luo, Dehong Teng, Zhongqiu Liu, Yingtang Zhou & Guochao Liao. (2022) Discovery of natural product-like spirooxindole derivatives as highly potent and selective LSD1/KDM1A inhibitors for AML treatment. Bioorganic Chemistry 120, pages 105596.
Crossref
Crossref
Xiangyu Zhang, Xinran Wang, Tianxiao Wu, Wenbo Yin, Jiangkun Yan, Yixiang Sun & Dongmei Zhao. (2022) Therapeutic potential of targeting LSD1/ KDM1A in cancers. Pharmacological Research 175, pages 105958.
Crossref
Crossref
Xiangyu Zhang, Yixiang Sun, Ziheng Zhang, Hanxun Wang, Jian Wang & Dongmei Zhao. (2021) Intermolecular insights into allosteric inhibition of histone lysine-specific demethylase 1. Biochimica et Biophysica Acta (BBA) - General Subjects 1865:11, pages 129990.
Crossref
Crossref
Yimeng Du, Yuqing Zhang, Meirong Huang, Shushu Wang, Jianzheng Wang, Kongke Liao, Xiaojun Wu, Qiang Zhou, Xinhao Zhang, Yun-Dong Wu & Tao Peng. (2021)
Systematic investigation of the aza-Cope reaction for fluorescence imaging of formaldehyde
in vitro
and
in vivo
. Chemical Science 12:41, pages 13857-13869.
Crossref
Crossref
Ying-Chao Duan, Lin-Feng Jin, Hong-Mei Ren, Shao-Jie Zhang, Yue-Jiao Liu, Yong-Tao Xu, Zi-Hao He, Yu Song, Hang Yuan, Shu-Hui Chen & Yuan-Yuan Guan. (2021) Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer. European Journal of Medicinal Chemistry 220, pages 113453.
Crossref
Crossref
Xing-Jie Dai, Ying Liu, Lei-Peng Xue, Xiao-Peng Xiong, Ying Zhou, Yi-Chao Zheng & Hong-Min Liu. (2021) Reversible Lysine Specific Demethylase 1 (LSD1) Inhibitors: A Promising Wrench to Impair LSD1. Journal of Medicinal Chemistry 64:5, pages 2466-2488.
Crossref
Crossref
Feng Song, Yunqiang Bian, Jing Liu, Zhenghua Li, Li Zhao, Junman Fang, Yonghong Lai & Meng Zhou. (2021) Indole Alkaloids, Synthetic Dimers and Hybrids with Potential In Vivo Anticancer Activity. Current Topics in Medicinal Chemistry 21:5, pages 377-403.
Crossref
Crossref
Dong-Jun Fu, Jun Li & Bin Yu. (2021) Annual review of LSD1/KDM1A inhibitors in 2020. European Journal of Medicinal Chemistry 214, pages 113254.
Crossref
Crossref
Xing-Jie Dai, Ying Liu, Xiao-Peng Xiong, Lei-Peng Xue, Yi-Chao Zheng & Hong-Min Liu. (2020) Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective. Journal of Medicinal Chemistry 63:23, pages 14197-14215.
Crossref
Crossref
Sarder Arifuzzaman, Mst Reshma Khatun & Rabeya Khatun. (2020) Emerging of lysine demethylases (KDMs): From pathophysiological insights to novel therapeutic opportunities. Biomedicine & Pharmacotherapy 129, pages 110392.
Crossref
Crossref
Xinran Wang, Cai Zhang, Xiangyu Zhang, Jiangkun Yan, Jiming Wang, Qinwen Jiang, Liyu Zhao, Dongmei Zhao & Maosheng Cheng. (2020) Design, synthesis and biological evaluation of tetrahydroquinoline-based reversible LSD1 inhibitors. European Journal of Medicinal Chemistry 194, pages 112243.
Crossref
Crossref
Xingrui He, Yuan Gao, Zi Hui, Guodong Shen, Shuo Wang, Tian Xie & Xiang-Yang Ye. (2020) 4-Hydroxy-3-methylbenzofuran-2-carbohydrazones as novel LSD1 inhibitors. Bioorganic & Medicinal Chemistry Letters 30:10, pages 127109.
Crossref
Crossref
Wen-juan Liu, Yue Du, Ru Wen, Ming Yang & Jian Xu. (2020) Drug resistance to targeted therapeutic strategies in non-small cell lung cancer. Pharmacology & Therapeutics 206, pages 107438.
Crossref
Crossref
Daniela Tomaselli, Alessia Lucidi, Dante Rotili & Antonello Mai. (2019) Epigenetic polypharmacology: A new frontier for epi‐drug discovery. Medicinal Research Reviews 40:1, pages 190-244.
Crossref
Crossref
Panagiotis Karakaidos, John Verigos & Angeliki Magklara. (2019) LSD1/KDM1A, a Gate-Keeper of Cancer Stemness and a Promising Therapeutic Target. Cancers 11:12, pages 1821.
Crossref
Crossref
Tayaba Ismail, Hyun-Kyung Lee, Chowon Kim, Taejoon Kwon, Tae Joo Park & Hyun-Shik Lee. (2018) KDM1A microenvironment, its oncogenic potential, and therapeutic significance. Epigenetics & Chromatin 11:1.
Crossref
Crossref
Iris F. Macheleidt, Priya S. Dalvi, So‐Young Lim, Sonja Meemboor, Lydia Meder, Olivia Käsgen, Marion Müller, Karolin Kleemann, Lingyu Wang, Peter Nürnberg, Vanessa Rüsseler, Stephan C. Schäfer, Esther Mahabir, Reinhard Büttner & Margarete Odenthal. (2018)
Preclinical studies reveal that
LSD
1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations
. Molecular Oncology 12:11, pages 1965-1979.
Crossref
Crossref
Siyuan Xu, Chen Zhou, Rongfeng Liu, Qihua Zhu, Yungen Xu, Fei Lan & Xiaoming Zha. (2018) Optimization of 5-arylidene barbiturates as potent, selective, reversible LSD1 inhibitors for the treatment of acute promyelocytic leukemia. Bioorganic & Medicinal Chemistry 26:17, pages 4871-4880.
Crossref
Crossref
Hideaki Niwa, Shin Sato, Tomoko Hashimoto, Kenji Matsuno & Takashi Umehara. (2018) Crystal Structure of LSD1 in Complex with 4-[5-(Piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile. Molecules 23:7, pages 1538.
Crossref
Crossref
Clemens Zwergel, Giulia Stazi, Antonello Mai & Sergio Valente. (2018) Trends of LSD1 inhibitors in viral infections. Future Medicinal Chemistry 10:10, pages 1133-1136.
Crossref
Crossref
Chia-Lung Tsai, An-Shine Chao, Shih-Ming Jung, Chiao-Yun Lin, Angel Chao & Tzu-Hao Wang. (2018) Stress-induced phosphoprotein 1 acts as a scaffold protein for glycogen synthase kinase-3 beta-mediated phosphorylation of lysine-specific demethylase 1. Oncogenesis 7:3.
Crossref
Crossref
Johannes Schulz-Fincke, Mirjam Hau, Jessica Barth, Dina Robaa, Dominica Willmann, Andreas Kürner, Julian Haas, Gabriele Greve, Tinka Haydn, Simone Fulda, Michael Lübbert, Steffen Lüdeke, Tobias Berg, Wolfgang Sippl, Roland Schüle & Manfred Jung. (2018) Structure-activity studies on N -Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation. European Journal of Medicinal Chemistry 144, pages 52-67.
Crossref
Crossref
Yue-Yang Ji, Sen-Dong Lin, Yu-Jie Wang, Ming-Bo Su, Wei Zhang, Hendra Gunosewoyo, Fan Yang, Jia Li, Jie Tang, Yu-Bo Zhou & Li-Fang Yu. (2017) Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors. European Journal of Medicinal Chemistry 141, pages 101-112.
Crossref
Crossref
Ying-Chao Duan, Yong-Cheng Ma, Wen-Ping Qin, Li-Na Ding, Yi-Chao Zheng, Ying-Li Zhu, Xiao-Yu Zhai, Jing Yang, Chao-Ya Ma & Yuan-Yuan Guan. (2017) Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment. European Journal of Medicinal Chemistry 140, pages 392-402.
Crossref
Crossref
Xiaoli Fu, Peng Zhang & Bin Yu. (2017) Advances toward LSD1 inhibitors for cancer therapy. Future Medicinal Chemistry 9:11, pages 1227-1242.
Crossref
Crossref
Valentina Piano, Bruce A. Palfey & Andrea Mattevi. (2017) Flavins as Covalent Catalysts: New Mechanisms Emerge. Trends in Biochemical Sciences 42:6, pages 457-469.
Crossref
Crossref
Shuang Liu, Wenting Lu, Shouyun Li, Saisai Li, Jia Liu, Yuanyuan Xing, Shuzu Zhang, Joe Zhongxiang Zhou, Haiyan Xing, Yingxi Xu, Qing Rao, Chengjun Deng, Min Wang & Jianxiang Wang. (2017) Identification of JL1037 as a novel, specific, reversible lysine-specific demethylase 1 inhibitor that induce apoptosis and autophagy of AML cells. Oncotarget 8:19, pages 31901-31914.
Crossref
Crossref
Kristian HelinSaverio Minucci. (2017) The Role of Chromatin-Associated Proteins in Cancer. Annual Review of Cancer Biology 1:1, pages 355-377.
Crossref
Crossref
Shuai Wang, Li-Jie Zhao, Yi-Chao Zheng, Dan-Dan Shen, Er-Fei Miao, Xue-Peng Qiao, Li-Juan Zhao, Ying Liu, Ruilei Huang, Bin Yu & Hong-Min Liu. (2017) Design, synthesis and biological evaluation of [1,2,4]triazolo[1,5-a]pyrimidines as potent lysine specific demethylase 1 (LSD1/KDM1A) inhibitors. European Journal of Medicinal Chemistry 125, pages 940-951.
Crossref
Crossref
Emily L. Ricq, Jacob M. Hooker & Stephen J. Haggarty. (2016)
Toward development of epigenetic drugs for central nervous system disorders: Modulating neuroplasticity
via
H3K4 methylation
. Psychiatry and Clinical Neurosciences 70:12, pages 536-550.
Crossref
Crossref
Chiara Marabelli, Biagina Marrocco & Andrea Mattevi. (2016) The growing structural and functional complexity of the LSD1/KDM1A histone demethylase. Current Opinion in Structural Biology 41, pages 135-144.
Crossref
Crossref
Jingxin Feng, Guiying Xu, Jiwei Liu, Na Zhang, Lili Li, Jiafei Ji, Jianchao Zhang, Lian Zhang, Guannan Wang, Xiuli Wang, Jiang Tan, Baiqu Huang, Jun Lu & Yu Zhang. (2016) Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer. Breast Cancer Research and Treatment 159:3, pages 443-456.
Crossref
Crossref
Valentina Speranzini, Dante RotiliGiuseppe CiossaniSimona PilottoBiagina MarroccoMariantonietta Forgione, Alessia Lucidi, Federico Forneris, Parinaz Mehdipour, Sameer Velankar, Antonello MaiAndrea Mattevi. (2016) Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features. Science Advances 2:9.
Crossref
Crossref