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Current Opinion on Therapeutic Patents Volume 3, 1993 - Issue 5
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Original Article

Overview: Recent Advances in Angiotensin II Receptor Antagonists

David T Dudley Departments of Signal Transduction and Chemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, MI, 48105, USA
&
James M Hamby Departments of Signal Transduction and Chemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, MI, 48105, USA
Pages 581-596 | Published online: 03 Mar 2008

Citations (7)

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Read on this site (3)

John C Hodges. (1994) Overview Cardiovascular & Renal: Angiotensin antagonists: agents that interact with the AT2 receptor and their potential therapeutic utilities. Expert Opinion on Therapeutic Patents 4:11, pages 1325-1338.
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. (1993) Patent Evaluation: Substituted aminopyrimidines as angiotensin II antagonists in treatment of hypertension and heart failure. Current Opinion on Therapeutic Patents 3:10, pages 1560-1561.
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. (1993) Patent Evaluation: Quinazolinones and pyridopyrimidinones as angiotensin II antagonists. Current Opinion on Therapeutic Patents 3:9, pages 1397-1399.
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Articles from other publishers (4)

A.M. Venkatesan, J.I. Levin, J.S. Baker, P.S. Chan, T. Bailey & J. Coupet. (1994) Substituted 4H-pyrido[1,2-a]pyrimidin-4-one angiotensin II receptor antagonists.. Bioorganic & Medicinal Chemistry Letters 4:1, pages 183-188.
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S.P. Watson, D. Middlemiss, M. Pass, T. Hubbard, T.A. Panchai, N.M. Heron, J.M.S. Paton, A. Butt, A.W. Dean, M. Donnelly & M.K. Bayliss. (1994) C-linked pyrazole biaryl tetrazoles as antagonists of angiotensin II Part II: pharmacokinetics and an efficient regioselective synthesis. Bioorganic & Medicinal Chemistry Letters 4:1, pages 151-156.
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Peter Bühlmayer, Pascual Furet, Leoluca Criscione, Marc de Gasparo, Steven Whitebread, Tibur Schmidlin, René Lattmann & Jeanette Wood. (1994) Valsartan, a potent, orally active angiotensin II antagonist developed from the structurally new amino acid series. Bioorganic & Medicinal Chemistry Letters 4:1, pages 29-34.
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M.D. Dowle, D.B. Judd, D. Middlemiss, D.I.C. Scopes, B.C. Ross, M. Pass, E. Tranquillini, T.I. Jack, J.E. Hobson, T.A. Panchal, P.G. Stuart, G.M. Drew, M.J. Robertson, A. Hilditch, K.L. Clark, A. Travers, A.A.E. Hunt, G.R. Manchee, D.G. Walker, P.J. Eddershaw, M. Donnelly & M.K. Bayliss. (1993) Benzofuran based angiotensin II antagonists related to GR117289: Part III; GR138950, a triflamide with high oral bioavailability.. Bioorganic & Medicinal Chemistry Letters 3:10, pages 2047-2050.
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