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Fumiaki Yokokawa. (2013) Recent progress on the discovery of non-peptidic direct renin inhibitors for the clinical management of hypertension. Expert Opinion on Drug Discovery 8:6, pages 673-690.
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Fumiaki Yokokawa & Jürgen Maibaum. (2008) Recent advances in the discovery of non-peptidic direct renin inhibitors as antihypertensives: new patent applications in years 2000 – 2008. Expert Opinion on Therapeutic Patents 18:6, pages 581-602.
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Articles from other publishers (6)
Randy L. Webb, Nikolaus Schiering, Richard Sedrani & Jürgen Maibaum. (2010) Direct Renin Inhibitors as a New Therapy for Hypertension. Journal of Medicinal Chemistry 53:21, pages 7490-7520.
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Rolf Güller, Alfred Binggeli, Volker Breu, Daniel Bur, Walter Fischli, Georges Hirth, Christian Jenny, Manfred Kansy, François Montavon, Marcel Müller, Christian Oefner, Heinz Stadler, Eric Vieira, Maurice Wilhelm, Wolfgang Wostl & Hans Peter Märki. (1999) Piperidine-renin inhibitors compounds with improved physicochemical properties. Bioorganic & Medicinal Chemistry Letters 9:10, pages 1403-1408.
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C Oefner, A Binggeli, V Breu, D Bur, J-P Clozel, A D'Arcy, A Dorn, W Fischli, F Grüninger, R Güller, G Hirth, HP Märki, S Mathews, M Müller, RG Ridley, H Stadier, E Vieira, M Wilhelm, FK Winkler & W Wostl. (1999) Renin inhibition by substituted piperidines: A novel paradigm for the inhibition of monomeric aspartic proteinases?. Chemistry & Biology 6:3, pages 127-131.
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Bruno Simoneau, Pierre Lavallée, Paul C. Anderson, Murray Bailey, Gary Bantle, Sylvie Berthiaume, Catherine Chabot, Gulrez Fazal, Ted Halmos, William W. Ogilvie, Marc-André Poupart, Bounkham Thavonekham, Zhili Xin, Diane Thibeault, Gordon Bolger, Maret Panzenbeck, Raymond Winquist & Grace L. Jung. (1999) Discovery of non-peptidic P 2 –P 3 butanediamide renin inhibitors with high oral efficacy. Bioorganic & Medicinal Chemistry 7:3, pages 489-508.
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Grace L. Jung, Paul C. Anderson, Murray Bailey, Monique Baillet, Gary W. Bantle, Sylvie Berthiaume, Pierre Lavallée, Montse Llinas-Brunet, Bounkham Thavonekham, Diane Thibeault & Bruno Simoneau. (1998) Novel small renin inhibitors containing 4,5- or 3,5-dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2P3 sites. Bioorganic & Medicinal Chemistry 6:12, pages 2317-2336.
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Bruce A. Lefker, William A. Hada, Ann S. Wright, William H. Martin, Ingrid A. Stock, Gayle K. Schulte, Jay Pandit, Dennis E. Danley, Mark J. Ammirati & Scott F. Sneddon. (1995) Rational design, synthesis, and X-ray structure of renin inhibitors with extended P1 sidechains. Bioorganic & Medicinal Chemistry Letters 5:22, pages 2623-2626.
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