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Expert Opinion on Therapeutic Patents Volume 6, 1996 - Issue 12
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Patent Update Oncologic, Endocrine & Metabolic: Oncologic, Endocrine & Metabolic: Inhibitors of protein farnesylation

Samuel L Graham Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA, 19486, USA
&
Theresa M Williams Samuel L Graham & Theresa M Williams, Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA, 19486, USA
Pages 1295-1304 | Published online: 29 Feb 2008

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Theresa M Williams. (1998) Inhibitors of protein farnesylation 1998. Expert Opinion on Therapeutic Patents 8:5, pages 553-569.
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Ernesto Menta & Manlio Palumbo. (1997) Novel antineoplastic agents. Expert Opinion on Therapeutic Patents 7:12, pages 1401-1426.
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Articles from other publishers (14)

Stéphanie Blanchard, Ivan Rodriguez, Catherine Kuehm-Caubère, Pierre Renard, Bruno Pfeiffer, Gérald Guillaumet & Paul Caubère. (2002) Hetarynic synthesis and chemical transformation of dihydrodipyridopyrazines. Tetrahedron 58:18, pages 3513-3524.
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Herbert I. Hurwitz & Patrick J. Casey. 2002. Peptide-Lipid Interactions. Peptide-Lipid Interactions 531 550 .
Jackson B. Gibbs. 2001. Protein Lipidation. Protein Lipidation 81 103 .
Christopher J. Dinsmore, Theresa M. Williams, Timothy J. O'Neill, Dongming Liu, Elaine Rands, J.Christopher Culberson, Robert B. Lobell, Kenneth S. Koblan, Nancy E. Kohl, Jackson B. Gibbs, Allen I. Oliff, Samuel L. Graham & George D. Hartman. (1999) Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase. Bioorganic & Medicinal Chemistry Letters 9:23, pages 3301-3306.
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Marco Scarsi, Nicolas Majeux & Amedeo Caflisch. (1999) Hydrophobicity at the surface of proteins. Proteins: Structure, Function, and Genetics 37:4, pages 565-575.
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Giuseppe Caliendo, Ferdinando Fiorino, Paolo Grieco, Elisa Perissutti, Stefania De Luca, Ada Giuliano, Giovanni Santelli, Daniela Califano, Beatrice Severino & Vincenzo Santagada. (1999) Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids. Il Farmaco 54:11-12, pages 785-790.
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Neville J. Anthony, Robert P. Gomez, Micheal D. Schaber, Scott D. Mosser, Kelly A. Hamilton, Timothy J. O'Neil, Kenneth S. Koblan, Samuel L. Graham, George D. Hartman, Daksha Shah, Elaine Rands, Nancy E. Kohl, Jackson B. Gibbs & Allen I. Oliff. (1999) Design and in Vivo Analysis of Potent Non-Thiol Inhibitors of Farnesyl Protein Transferase. Journal of Medicinal Chemistry 42:17, pages 3356-3368.
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Terrence M. Ciccarone, Suzanne C. MacTough, Theresa M. Williams, Christopher J. Dinsmore, Timothy J. O'Neill, Daksha Shah, J.Christopher Culberson, Kenneth S. Koblan, Nancy E. Kohl, Jackson B. Gibbs, Allen I. Oliff, Samuel L. Graham & George D. Hartman. (1999) Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase. Bioorganic & Medicinal Chemistry Letters 9:14, pages 1991-1996.
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Theresa M. Williams & Christopher J. Dinsmore. 1999. 273 314 .
Michael J. Breslin, S.Jane deSolms, Elizabeth A. Giuliani, Gerald E. Stokker, Samuel L. Graham, David L. Pompliano, Scott D. Mosser, Kelly A. Hamilton & John H. Hutchinson. (1998) Potent, non-thiol inhibitors of farnesyltransferase. Bioorganic & Medicinal Chemistry Letters 8:23, pages 3311-3316.
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Klaus Hinterding, Patrizia Hagenbuch, Janos Rétey & Herbert Waldmann. (1998) Synthese und In-vitro-Evaluierung des Ras-Farnesyltransferase-Inhibitors Pepticinnamin E. Angewandte Chemie 110:9, pages 1298-1301.
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Hua-Wen Fu, Lorena S. Beese & Patrick J. Casey. (1998) Kinetic Analysis of Zinc Ligand Mutants of Mammalian Protein Farnesyltransferase. Biochemistry 37:13, pages 4465-4472.
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Jackson B Gibbs, Samuel L Graham, George D Hartman, Kenneth S Koblan, Nancy E Kohl, Charles A Omer & Allen Oliff. (1997) Farnesyltransferase inhibitors versus Ras inhibitors. Current Opinion in Chemical Biology 1:2, pages 197-203.
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Charles A. Omer & Nancy E. Kohl. (1997) CA1A2X-competitive inhibitors of farnesyltransferase as anti-cancer agents. Trends in Pharmacological Sciences 18:4, pages 437-444.
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