Advanced search
Publication Cover
Expert Opinion on Therapeutic Patents Volume 7, 1997 - Issue 4
Submit an article Journal homepage
43
Views
18
CrossRef citations to date
0
Altmetric
Review

5-HT1B/1D antagonists and depression

Serge Halazy Division of Medicinal Chemistry IV, Centre de Recherche Pierre Fabre, 17 Avenue Jean Moulin, 81106 Castres Cédex, France
,
Marie Lamothe Division of Medicinal Chemistry IV, Centre de Recherche Pierre Fabre, 17 Avenue Jean Moulin, 81106 Castres Cédex, France
&
Catherine Jorand-Lebrun Division of Medicinal Chemistry IV, Centre de Recherche Pierre Fabre, 17 Avenue Jean Moulin, 81106 Castres Cédex, France
Pages 339-352 | Published online: 25 Feb 2005

Citations (18)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Serge Halazy. (1999) G-protein coupled receptors bivalent ligands and drug design. Expert Opinion on Therapeutic Patents 9:4, pages 431-446.
Read now
Frank Kerrigan. (1998) Antidepressant patents: 1995 - 1997. Expert Opinion on Therapeutic Patents 8:4, pages 439-460.
Read now

Articles from other publishers (16)

Navneet Bung, Sowmya Ramaswamy Krishnan & Arijit Roy. (2022) An In Silico Explainable Multiparameter Optimization Approach for De Novo Drug Design against Proteins from the Central Nervous System . Journal of Chemical Information and Modeling 62:11, pages 2685-2695.
Crossref
Penelope Lowe, Amir Krivoy, Lilla Porffy, Erna Henriksdottir, Whiskey Eromona & Sukhwinder S. Shergill. (2017) When the drugs don’t work: treatment-resistant schizophrenia, serotonin and serendipity. Therapeutic Advances in Psychopharmacology 8:1, pages 63-70.
Crossref
Nabeel Nabulsi, Yiyun Huang, David Weinzimmer, Jim Ropchan, James J. Frost, Timothy McCarthy, Richard E. Carson & Yu-Shin Ding. (2010) High-resolution imaging of brain 5-HT1B receptors in the rhesus monkey using [11C]P943. Nuclear Medicine and Biology 37:2, pages 205-214.
Crossref
Charles S. Elmore, Mark E. Powell & J. Richard Heys. (2008) Syntheses of AZ12320927 labeled with H‐3, C‐14, and H‐2. Journal of Labelled Compounds and Radiopharmaceuticals 51:9, pages 343-346.
Crossref
Carey L. Horchler, John P. McCauleyJr.Jr., James E. Hall, Dean H. Snyder, W. Craig Moore, Thomas J. Hudzik & Marc J. Chapdelaine. (2007) Synthesis of novel quinolone and quinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amides: A late-stage diversification approach to potent 5HT1B antagonists. Bioorganic & Medicinal Chemistry 15:2, pages 939-950.
Crossref
Katarina Varnäs, Håkan Hall, Pascal Bonaventure & Göran Sedvall. (2001) Autoradiographic mapping of 5-HT1B and 5-HT1D receptors in the post mortem human brain using [3H]GR 125743. Brain Research 915:1, pages 47-57.
Crossref
Yi Liao, Henning Böttcher, Jürgen Harting, Hartmut Greiner, Christoph van Amsterdam, Thomas Cremers, Staffan Sundell, Joachim März, Wilfried Rautenberg & Håkan Wikström. (2000) New Selective and Potent 5-HT 1B/1D Antagonists:  Chemistry and Pharmacological Evaluation of N -Piperazinylphenyl Biphenylcarboxamides and Biphenylsulfonamides . Journal of Medicinal Chemistry 43:3, pages 517-525.
Crossref
P. Bonaventure, L. Umans, M. H. M. Bakker, P. Cras, X. Langlois, W. H. M. L. Luyten, A. A. H. P. Megens, L. Serneels, F. Van Leuven & J. E. Leysen. (1999) Humanization of Mouse 5-Hydroxytryptamine 1B Receptor Gene by Homologous Recombination: In Vitro and In Vivo Characterization . Molecular Pharmacology 56:1, pages 54-67.
Crossref
Sophie Maurel, Rudy Schreiber & Jean de Vry. (1998) Lack of potentiation of the anti-alcohol effects of fluoxetine by pindolol in alcohol-preferring caa rats. Progress in Neuro-Psychopharmacology and Biological Psychiatry 22:8, pages 1361-1378.
Crossref
P Bonaventure, X Langlois & J.E Leysen. (1998) Co-localization of 5-HT1B- and 5-HT1D receptor mRNA in serotonergic cell bodies in guinea pig dorsal raphé nucleus: a double labeling in situ hybridization histochemistry study. Neuroscience Letters 254:2, pages 113-116.
Crossref
Michel Perez, Catherine Jorand-Lebrun, Petrus J. Pauwels, Isabelle Pallard & Serge Halazy. (1998) Dimers of 5HT 1 ligands preferentially bind to 5HT1b1d receptor subtypes. Bioorganic & Medicinal Chemistry Letters 8:11, pages 1407-1412.
Crossref
M. Briley & C. Moret. 1998. Trends in Drug Research II, Proceedings of the 11th Noordwijkerhout-Camerino Symposium. Trends in Drug Research II, Proceedings of the 11th Noordwijkerhout-Camerino Symposium 75 84 .
Laramie M. Gaster & Frank D. King. 1998. 21 30 .
C. Jorand-Lebrun, P.J. Pauwels, C. Palmier, P. Chopin, C. Moret, M. Marien & S. Halazy. (1997) Arylpiperazide derivatives of phenylpiperazines as a new class of potent and selective 5-HT1B receptor antagonists. Bioorganic & Medicinal Chemistry Letters 7:24, pages 3183-3188.
Crossref
Catherine Jorand-Lebrun, Petrus J. Pauwels, Christiane Palmier, Chantal Moret, Philippe Chopin, Michel Perez, Marc Marien & Serge Halazy. (1997) 5-HT 1B Receptor Antagonist Properties of Novel Arylpiperazide Derivatives of 1-Naphthylpiperazine . Journal of Medicinal Chemistry 40:24, pages 3974-3978.
Crossref
Marie Lamothe, Petrus J. Pauwels, Karine Belliard, Philippe Schambel & Serge Halazy. (1997) Differentiation between Partial Agonists and Neutral 5-HT 1B Antagonists by Chemical Modulation of 3-[3-( N,N -Dimethylamino)propyl]-4-hydroxy- N -[4-(pyridin-4-yl)phenyl]benzamide (GR-55562) . Journal of Medicinal Chemistry 40:22, pages 3542-3550.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.