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Expert Opinion on Therapeutic Patents Volume 8, 1998 - Issue 2
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Review

Quinoline antimalarials

Robert G Ridley Pharmaceuticals Division, Dept. PRPI-D, F Hoffmann-La Roche, CH-4070 Basel, Switzerland
&
Alan T Hudson Pharmaceuticals Division, Dept. PRPI-D, F Hoffmann-La Roche, CH-4070 Basel, Switzerland
Pages 121-136 | Published online: 25 Feb 2005

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Read on this site (2)

Timothy J Egan. (2001) Quinoline antimalarials. Expert Opinion on Therapeutic Patents 11:2, pages 185-209.
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Gary H Posner. (1998) Antimalarial peroxides in the qinghaosu (artemisinin) and yingzhaosu families. Expert Opinion on Therapeutic Patents 8:11, pages 1487-1493.
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Articles from other publishers (21)

Bianca Seitz, Thomas Schneider, Nikola Majstorovic, Maximilian Fleischmann & Gerhard Maas. (2021) Reactions of 1-Trifluoromethylprop-2-yne 1-Iminium Salts with Nitroanilines: Synthesis of 4-Trifluoromethylnitroquinolines and 1,2,3-Trisubstituted 5-Trifluoromethylpyrroles. Synthesis 54:08, pages 2057-2069.
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Juanjuan Chen, Yuting Fang, Hong Liu, Naisheng Chen, Shengping Chen & Jinping Xue. (2018) Quinolin-8-yloxy-substituted zinc(II) phthalocyanines for enhanced in vitro photodynamic therapy . Journal of Porphyrins and Phthalocyanines 22:09n10, pages 807-813.
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Erika Murce, Teobaldo Ricardo Cuya-Guizado, Helmut Isaac Padilla-Chavarria, Tanos Celmar Costa França & Andre Silva Pimentel. (2015) Structure-based de novo design, molecular docking and molecular dynamics of primaquine analogues acting as quinone reductase II inhibitors. Journal of Molecular Graphics and Modelling 62, pages 235-244.
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Xiao Jia, Feng-Feng Yang, Jun Li, Jian-Yong Liu & Jin-Ping Xue. (2013) Synthesis and in Vitro Photodynamic Activity of Oligomeric Ethylene Glycol–Quinoline Substituted Zinc(II) Phthalocyanine Derivatives. Journal of Medicinal Chemistry 56:14, pages 5797-5805.
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Matteo Staderini, Nieves Cabezas, Maria Laura Bolognesi & J. Carlos Menéndez. (2013) Solvent- and chromatography-free amination of π-deficient nitrogen heterocycles under microwave irradiation. A fast, efficient and green route to 9-aminoacridines, 4-aminoquinolines and 4-aminoquinazolines and its application to the synthesis of the drugs amsacrine and bistacrine. Tetrahedron 69:3, pages 1024-1030.
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Diego González Cabrera, Frederic Douelle, Tzu-Shean Feng, Aloysius T. Nchinda, Yassir Younis, Karen L. White, Quoc Wu, Eileen Ryan, Jeremy N. Burrows, David Waterson, Michael J. Witty, Sergio Wittlin, Susan A. Charman & Kelly Chibale. (2011) Novel Orally Active Antimalarial Thiazoles. Journal of Medicinal Chemistry 54:21, pages 7713-7719.
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Albert J. Ndakala, Richard K. Gessner, Patricia W. Gitari, Natasha October, Karen L. White, Alan HudsonFoluke Fakorede, David M. Shackleford, Marcel Kaiser, Clive YeatesSusan A. Charman & Kelly Chibale. (2011) Antimalarial Pyrido[1,2- a ]benzimidazoles . Journal of Medicinal Chemistry 54:13, pages 4581-4589.
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Kristin Janz & Neelu Kaila. (2009) Bromodecarboxylation of Quinoline Salicylic Acids: Increasing the Diversity of Accessible Substituted Quinolines. The Journal of Organic Chemistry 74:22, pages 8874-8877.
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Juliana Martha Sá, Olivia Twu, Karen Hayton, Sahily Reyes, Michael P. Fay, Pascal Ringwald & Thomas E. Wellems. (2009) Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine . Proceedings of the National Academy of Sciences 106:45, pages 18883-18889.
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Anirban Karmakar, Dipjyoti Kalita & Jubaraj B. Baruah. (2009) Structural study on few co-crystals and a salt of quinoline derivatives having amide bond. Journal of Molecular Structure 935:1-3, pages 47-52.
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Dipjyoti Kalita, Rupam Sarma & Jubaraj B. Baruah. (2009) Catalytic alcoholysis of quinolin-8-yl esters by manganese complexes. Inorganic Chemistry Communications 12:6, pages 569-571.
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Donelly A. van Schalkwyk & Timothy J. Egan. (2006) Quinoline-resistance reversing agents for the malaria parasite Plasmodium falciparum. Drug Resistance Updates 9:4-5, pages 211-226.
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Bronwen Naudé, Joseph A. Brzostowski, Alan R. Kimmel & Thomas E. Wellems. (2005) Dictyostelium discoideum Expresses a Malaria ChloroquineResistance Mechanism upon Transfection with Mutant, but Not Wild-type,Plasmodium falciparum TransporterPfCRT. Journal of Biological Chemistry 280:27, pages 25596-25603.
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Kanyile K. Ncokazi & Timothy J. Egan. (2005) A colorimetric high-throughput β-hematin inhibition screening assay for use in the search for antimalarial compounds. Analytical Biochemistry 338:2, pages 306-319.
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Robert G. Ridley. (2002) Medical need, scientific opportunity and the drive for antimalarial drugs. Nature 415:6872, pages 686-693.
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Yae Kurosawa, Arnulf Dorn, Michiko Kitsuji-Shirane, Hisao Shimada, Tomoko Satoh, Hugues Matile, Werner Hofheinz, Raffaello Masciadri, Manfred Kansy & Robert G. Ridley. (2000) Hematin Polymerization Assay as a High-Throughput Screen for Identification of New Antimalarial Pharmacophores. Antimicrobial Agents and Chemotherapy 44:10, pages 2638-2644.
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Gry Stensrud, Sverre A Sande, Solveig Kristensen & Gro Smistad. (2000) Formulation and characterisation of primaquine loaded liposomes prepared by a pH gradient using experimental design. International Journal of Pharmaceutics 198:2, pages 213-228.
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C. Biot, L. Delhaes, C.M. N'Diaye, L.A. Maciejewski, D. Camus, D. Dive & J.S. Brocard. (1999) Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorganic & Medicinal Chemistry 7:12, pages 2843-2847.
Crossref
Sudha Rani Vippagunta, Arnulf Dorn, Hugues Matile, Apurba K. Bhattacharjee, Jean M. Karle, William Y. Ellis, Robert G. Ridley & Jonathan L. Vennerstrom. (1999) Structural Specificity of Chloroquine−Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth. Journal of Medicinal Chemistry 42:22, pages 4630-4639.
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C Biot, L Delhaes, H Abessolo, O Domarle, L.A Maciejewski, M Mortuaire, P Delcourt, P Deloron, D Camus, D Dive & J.S Brocard. (1999) Novel metallocenic compounds as antimalarial agents. Study of the position of ferrocene in chloroquine. Journal of Organometallic Chemistry 589:1, pages 59-65.
Crossref
Robert G. Ridley. (1998) Malaria: Dissecting chloroquine resistance. Current Biology 8:10, pages R346-R349.
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