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Recent developments in neuronal nicotinic acetylcholine receptor modulators

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Pages 991-1015 | Published online: 25 Feb 2005

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Steven R Pliszka. (2001) New developments in psychopharmacology of attention deficit hyperactivity disorder. Expert Opinion on Investigational Drugs 10:10, pages 1797-1807.
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Linda P Dwoskin, Rui Xu, Joshua T Ayers & Peter A Crooks. (2000) Recent developments in neuronal nicotinic acetylcholine receptor antagonists. Expert Opinion on Therapeutic Patents 10:10, pages 1561-1581.
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Articles from other publishers (19)

Gulnara N. Kadikova, Vladimir A. D’yakonov, Ramil N. Nasretdinov, Lilya U. Dzhemileva & Usein M. Dzhemilev. (2020) Synthesis of new alkynyl containing 9-azabicyclo[4.2.1]nonatrienes from diynes and azepines. Mendeleev Communications 30:3, pages 318-319.
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Bruno Tasso, Caterina Canu Boido, Emanuela Terranova, Cecilia Gotti, Loredana Riganti, Francesco Clementi, Roberto Artali, Gabriella Bombieri, Fiorella Meneghetti & Fabio Sparatore. (2009) Synthesis, Binding, and Modeling Studies of New Cytisine Derivatives, as Ligands for Neuronal Nicotinic Acetylcholine Receptor Subtypes. Journal of Medicinal Chemistry 52:14, pages 4345-4357.
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Daniel Yohannes, Camilla P. Hansen, Srinivasa Rao Akireddy, Terry A. Hauser, Melanie N. Kiser, Nicholas J. Gurnon, Cynthia S. Day, Balwinder Bhatti & William S. Caldwell. (2008) First Total Synthesis of (±)-3-Hydroxy-11-norcytisine: Structure Confirmation and Biological Characterization. Organic Letters 10:23, pages 5353-5356.
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Daniel Yohannes, Kristen Procko, Lorraine A. Lebel, Carol B. Fox & Brian T. O’Neill. (2008) Deconstructing cytisine: The syntheses of (±)-cyfusine and (±)-cyclopropylcyfusine, fused ring analogs of cytisine. Bioorganic & Medicinal Chemistry Letters 18:7, pages 2316-2319.
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Qi Sun, Cai-Qin Yue, Jia Ye, Chang-Ling Li, Tie-Ming Cheng & Run-Tao Li. (2007) Unique spirocyclopiperazinium salt III: Further investigation of monospirocyclopiperazinium (MSPZ) salts as potential analgesics. Bioorganic & Medicinal Chemistry Letters 17:22, pages 6245-6249.
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Peter A Crooks, Joshua T Ayers, Rui Xu, Sangeetha P Sumithran, Vladimir P Grinevich, Lincoln H Wilkins, A.Gabriela Deaciuc, David D Allen & Linda P Dwoskin. (2004) Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic & Medicinal Chemistry Letters 14:8, pages 1869-1874.
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Jing-Chao Dong, Xin Wang, Run-Tao Li, Hong-Mei Zhang, Tie-Ming Cheng & Chang-Ling Li. (2003) Synthesis and analgesic activity of hydrochlorides and quaternary ammoniums of epibatidine incorporated with amino acid ester. Bioorganic & Medicinal Chemistry Letters 13:24, pages 4327-4329.
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Gaëlle Roger, Béatrice Lagnel, Jacques Rouden, Laurent Besret, Héric Valette, Stéphane Demphel, JaganMohan Gopisetti, Christine Coulon, Michele Ottaviani, Lori A Wrenn, Sharon R Letchworth, Georg A Bohme, Jesus Benavides, Marie-Claire Lasne, Michel Bottlaender & Frédéric Dollé. (2003) Synthesis of a [2-Pyridinyl-18F]-labelled fluoro derivative of (−)-Cytisine as a candidate radioligand for brain nicotinic α4β2 receptor imaging with PET. Bioorganic & Medicinal Chemistry 11:24, pages 5333-5343.
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Xin Wang, Feng-Li Gao, Hong-Bin Piao, Tie-Ming Cheng & Run-Tao Li. (2003) Unique spirocyclopiperazinium salt. Part 2: synthesis and structure–activity relationship of dispirocyclopiperazinium salts as analgesics. Bioorganic & Medicinal Chemistry Letters 13:10, pages 1729-1732.
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Feng-Li Gao, Xin Wang, Hong-Mei Zhang, Tie-Ming Cheng & Run-Tao Li. (2003) Unique spirocyclopiperazinium salt I: synthesis and structure–Activity relationship of spirocyclopiperazinium salts as analgesics. Bioorganic & Medicinal Chemistry Letters 13:9, pages 1535-1537.
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Caterina Canu Boido, Bruno Tasso, Vito Boido & Fabio Sparatore. (2003) Cytisine derivatives as ligands for neuronal nicotine receptors and with various pharmacological activities. Il Farmaco 58:3, pages 265-277.
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Donald J. AbrahamClark N. EidJr.Jr., Yong‐Jin Wu & Gene G. Kinney. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 779 836 .
Joshua T Ayers, Linda P Dwoskin, A.Gabriela Deaciuc, Vladimir P Grinevich, Jun Zhu & Peter A Crooks. (2002) bis-Azaaromatic quaternary ammonium analogues: ligands for α4β2* and α7* subtypes of neuronal nicotinic receptors. Bioorganic & Medicinal Chemistry Letters 12:21, pages 3067-3071.
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Rui Xu, Linda P. Dwoskin, Vladimir Grinevich, Sangeetha P. Sumithran & Peter A. Crooks. (2002) Synthesis and evaluation of conformationally restricted pyridino N ‐alkylated nicotine analogs as nicotinic acetylcholine receptor antagonists . Drug Development Research 55:3, pages 173-186.
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Astrid Stehl, Gunther Seitz & Karen Schulz. (2002) Racemic and enantiopure 4-(piperidine-2′-yl)-pyridazines: novel synthesis of anabasine-analogues with potential nicotinic acetylcholine receptor agonist activity—a new approach via Diels–Alder reaction with inverse electron demand. Tetrahedron 58:7, pages 1343-1354.
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Daniela Gündisch, Thomas Kämpchen, Simone Schwarz, Gunther Seitz, Johanna Siegl & Thomas Wegge. (2002) Syntheses and evaluation of pyridazine and pyrimidine Containing bioisosteres of (±)-Pyrido[3.4-b]homotropane and Pyrido-[3.4-b]tropane as novel nAChR ligands. Bioorganic & Medicinal Chemistry 10:1, pages 1-9.
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P Imming. (2001) Syntheses and evaluation of halogenated cytisine derivatives and of bioisosteric thiocytisine as potent and selective nAChR ligands. European Journal of Medicinal Chemistry 36:4, pages 375-388.
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Thierry Giard, Marie-Claire Lasne & Jean-Christophe Plaquevent. (1999) Pyrrolidines bearing a quaternary α-stereogenic center. Part 1: Synthesis of analogs of ABT-418, a powerful nicotinic agonist. Tetrahedron Letters 40:30, pages 5495-5497.
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Daqing Che, Johanna Siegl & Gunther Seitz. (1999) Synthesis of chiral 2-(2′-pyrrolidinyl)pyridines from (S)- and (R)-proline: potential ligands of the neuronal nicotinic acetylcholine receptors. Tetrahedron: Asymmetry 10:3, pages 573-585.
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