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Expert Opinion on Therapeutic Patents Volume 9, 1999 - Issue 10
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Review

Tau protein as a therapeutic target in Alzheimer’s disease and other neurodegenerative disorders

Andrew J Larner Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
Pages 1359-1370 | Published online: 25 Feb 2005

Citations (7)

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Ana Castro & Ana Martinez. (2000) Inhibition of tau phosphorylation: a new therapeutic strategy for the treatment of Alzheimer’s disease and other neurodegenerative disorders. Expert Opinion on Therapeutic Patents 10:10, pages 1519-1527.
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Articles from other publishers (6)

Ana Castro, Arantxa Encinas, Carmen Gil, Stefan Bräse, Williams Porcal, Concepción Pérez, Francisco J. Moreno & Ana Martínez. (2008) Non-ATP competitive glycogen synthase kinase 3β (GSK-3β) inhibitors: Study of structural requirements for thiadiazolidinone derivatives. Bioorganic & Medicinal Chemistry 16:1, pages 495-510.
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Vipin Kumar & A.K. Madan. (2005) Application of graph theory: prediction of glycogen synthase kinase-3 β inhibitory activity of thiadiazolidinones as potential drugs for the treatment of Alzheimer's disease. European Journal of Pharmaceutical Sciences 24:2-3, pages 213-218.
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Marie Knockaert, Paul Greengard & Laurent Meijer. (2002) Pharmacological inhibitors of cyclin-dependent kinases. Trends in Pharmacological Sciences 23:9, pages 417-425.
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Ana Martinez, Mercedes Alonso, Ana Castro, Concepción Pérez & Francisco J. Moreno. (2002) First Non-ATP Competitive Glycogen Synthase Kinase 3 β (GSK-3β) Inhibitors:  Thiadiazolidinones (TDZD) as Potential Drugs for the Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry 45:6, pages 1292-1299.
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Keshab Bhattacharya, Kenneth B. Rank, David B. Evans & Satish K. Sharma. (2001) Role of Cysteine-291 and Cysteine-322 in the Polymerization of Human Tau into Alzheimer-like Filaments. Biochemical and Biophysical Research Communications 285:1, pages 20-26.
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Maryse Leost, Christiane Schultz, Andreas Link, Yong‐Zhong Wu, Jacek Biernat, Eva‐Maria Mandelkow, James A. Bibb, Gretchen L. Snyder, Paul Greengard, Daniel W. Zaharevitz, Rick Gussio, Adrian M. Senderowicz, Edward A. Sausville, Conrad Kunick & Laurent Meijer. (2001) Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25. European Journal of Biochemistry 267:19, pages 5983-5994.
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