45
Views
20
CrossRef citations to date
0
Altmetric
Review

New inhibitors of tubulin polymerisation

Pages 1069-1081 | Published online: 25 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

A. D. McCormick, D. L. Slamon, E. M. Lenz, P. J. Phillips, C. D. King, D. Mckillop & D. W. Roberts. (2007) metabolism of a triclyclic alkaloid (M445526) in human liver microsomes and hepatocytes. Xenobiotica 37:9, pages 972-985.
Read now
Helge Prinz. (2002) Recent advances in the field of tubulin polymerization inhibitors. Expert Review of Anticancer Therapy 2:6, pages 695-708.
Read now
Qun Li & Hing L Sham. (2002) Discovery and development of antimitotic agents that inhibit tubulin polymerisation for the treatment of cancer. Expert Opinion on Therapeutic Patents 12:11, pages 1663-1702.
Read now
Thomas R Gadek & Denise A Ockey. (2002) Inhibitors of protein-protein interactions. Expert Opinion on Therapeutic Patents 12:3, pages 393-400.
Read now
Kenneth H Downing. (2000) Structural basis for the action of drugs that affect microtubule dynamics. Emerging Therapeutic Targets 4:2, pages 219-237.
Read now

Articles from other publishers (15)

Ramandeep Kaur, Gurneet Kaur, Rupinder Kaur Gill, Richard Soni & Jitender Bariwal. (2014) Recent developments in tubulin polymerization inhibitors: An overview. European Journal of Medicinal Chemistry 87, pages 89-124.
Crossref
Abdallah Hamze, Evelia Rasolofonjatovo, Olivier Provot, Céline Mousset, Damien Veau, Jordi Rodrigo, Jérôme Bignon, Jian-Miao Liu, Joanna Wdzieczak-Bakala, Sylviane Thoret, Joëlle Dubois, Jean-Daniel Brion & Mouad Alami. (2011) B-Ring-Modified isoCombretastatin A-4 Analogues Endowed with Interesting Anticancer Activities. ChemMedChem 6:12, pages 2179-2191.
Crossref
Alina Ghinet, Benoît Rigo, Jean-Pierre Hénichart, Delphine Le Broc-Ryckewaert, Jean Pommery, Nicole Pommery, Xavier Thuru, Bruno Quesnel & Philippe Gautret. (2011) Synthesis and biological evaluation of phenstatin metabolites. Bioorganic & Medicinal Chemistry 19:20, pages 6042-6054.
Crossref
Anne Zuse, Helge Prinz, Klaus Müller, Peter Schmidt, Eckhard G. Günther, Frank Schweizer, Jochen H.M. Prehn & Marek Los. (2007) 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity. European Journal of Pharmacology 575:1-3, pages 34-45.
Crossref
Michaela Pojarová, Doris Kaufmann, Robert Gastpar, Tsuyuki Nishino, Przemyslaw Reszka, Patrick J. Bednarski & Erwin von Angerer. (2007) [(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G2/M phase and apoptosis. Bioorganic & Medicinal Chemistry 15:23, pages 7368-7379.
Crossref
Doris Kaufmann, Michaela Pojarová, Susanne Vogel, Renate Liebl, Robert Gastpar, Dietmar Gross, Tsuyuki Nishino, Tobias Pfaller & Erwin von Angerer. (2007) Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells. Bioorganic & Medicinal Chemistry 15:15, pages 5122-5136.
Crossref
Aqeel Ahmed, Noël R. Peters, Megan K. Fitzgerald, James A. Watson,, F. Michael Hoffmann & Jon S. Thorson. (2006) Colchicine Glycorandomization Influences Cytotoxicity and Mechanism of Action. Journal of the American Chemical Society 128:44, pages 14224-14225.
Crossref
S. Mahboobi, A. Sellmer & T. Beckers. 2006. 719 750 .
Arie Zask, Gary Birnberg, Katherine Cheung, Joshua Kaplan, Chuan Niu, Emily Norton, Ronald Suayan, Ayako Yamashita, Derek Cole, Zhilian Tang, Girija Krishnamurthy, Robert Williamson, Gulnaz Khafizova, Sylvia Musto, Richard Hernandez, Tami Annable, Xiaoran Yang, Carolyn Discafani, Carl Beyer, Lee M. Greenberger, Frank Loganzo & Semiramis Ayral-Kaloustian. (2004) Synthesis and Biological Activity of Analogues of the Antimicrotubule Agent N ,β,β-Trimethyl- l -phenylalanyl- N -[(1 S ,2 E )-3-carboxy-1-isopropylbut-2-enyl]- N 1 ,3-dimethyl- l -valinamide (HTI-286) . Journal of Medicinal Chemistry 47:19, pages 4774-4786.
Crossref
Helge PrinzYukihito IshiiTakeo HiranoThomas StoiberJuan A. Camacho GomezPeter SchmidtHeiko DüssmannAngelika M. BurgerJochen H. M. PrehnEckhard G. GüntherEberhard UngerKazuo Umezawa. (2003) Novel Benzylidene-9(10 H )-anthracenones as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization . Journal of Medicinal Chemistry 46:15, pages 3382-3394.
Crossref
Rima S. Al-awar, James E. Ray, Richard M. Schultz, Sherri L. Andis, Joseph H. Kennedy, Richard E. Moore, Jian Liang, Trimurtulu Golakoti, Gottumukkala V. Subbaraju & Thomas H. Corbett. (2003) A Convergent Approach to Cryptophycin 52 Analogues:  Synthesis and Biological Evaluation of a Novel Series of Fragment A Epoxides and Chlorohydrins. Journal of Medicinal Chemistry 46:14, pages 2985-3007.
Crossref
Donna M Barron, Sabarni K Chatterjee, Rudravajhala Ravindra, Rebecca Roof, Erkan Baloglu, David G.I Kingston & Susan Bane. (2003) A fluorescence-based high-throughput assay for antimicrotubule drugs. Analytical Biochemistry 315:1, pages 49-56.
Crossref
Thomas R Gadek & John B Nicholas. (2003) Small molecule antagonists of proteins. Biochemical Pharmacology 65:1, pages 1-8.
Crossref
Qun Li, Keith W. Woods, Akiyo Claiborne, Stephen L. Gwaltney, II, Kenneth J. Barr, Gang Liu, Laura Gehrke, R.Bruce Credo, Yu Hua Hui, Jang Lee, Robert B. Warner, Peter Kovar, Michael A. Nukkala, Nicolette A. Zielinski, Stephen K. Tahir, Michael Fitzgerald, Ki H. Kim, Kennan Marsh, David Frost, Shi-Chung Ng, Saul Rosenberg & Hing L. Sham. (2002) Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent. Bioorganic & Medicinal Chemistry Letters 12:3, pages 465-469.
Crossref
Stephen L. GwaltneyIIII, Hovis M. Imade, Qun Li, Laura Gehrke, R.Bruce Credo, Robert B. Warner, Jang Yun Lee, Peter Kovar, David Frost, Shi-Chung Ng & Hing L. Sham. (2001) Novel sulfonate Derivatives: potent antimitotic agents. Bioorganic & Medicinal Chemistry Letters 11:13, pages 1671-1673.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.