Advanced search
Publication Cover
Expert Opinion on Investigational Drugs Volume 12, 2003 - Issue 1
Submit an article Journal homepage
348
Views
48
CrossRef citations to date
0
Altmetric
Review

Cannabinoids for gastrointestinal diseases: potential therapeutic applications

Giulia Di Carlo Department of Experimental Pharmacology, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy, Fax +39 081 678 403;
&
Angelo A Izzo Department of Experimental Pharmacology, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy, Fax +39 081 678 403;
Pages 39-49 | Published online: 02 Mar 2005

Citations (48)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Maria Notarnicola, Caterina Messa, Antonella Orlando, Maurizio Bifulco, Chiara Laezza, Patrizia Gazzerro & Maria Gabriella Caruso. (2008) Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines. Scandinavian Journal of Gastroenterology 43:1, pages 66-72.
Read now

Articles from other publishers (47)

Niccolò Chiaramonte & Nathalie Saraiva Rosa. 2023. Terpenes. Terpenes 56 93 .
Yang Zhao, Estatira Sepehr, Cory Vaught, Jeffrey Yourick & Robert L. Sprando. (2023) Development and validation of a fit-for-purpose UHPLC-ESI-MS/MS method for the quantitation of cannabinoids in different matrices. Journal of Chromatography B 1218, pages 123629.
Crossref
Bismarck Rezende, Allan Kardec Nogueira Alencar, Graziele Freitas de Bem, Fabrícia Lima Fontes-Dantas & Guilherme Carneiro Montes. (2023) Endocannabinoid System: Chemical Characteristics and Biological Activity. Pharmaceuticals 16:2, pages 148.
Crossref
Justin Bueno & Eric A. Greenbaum. (2021) (−)- trans -Δ 9 -Tetrahydrocannabiphorol Content of Cannabis sativa Inflorescence from Various Chemotypes . Journal of Natural Products 84:2, pages 531-536.
Crossref
Andrea Toschi, Giorgia Galiazzo, Andrea Piva, Claudio Tagliavia, Gemma Mazzuoli-Weber, Roberto Chiocchetti & Ester Grilli. (2021) Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum. Animals 11:2, pages 263.
Crossref
Agnese Stanzani, Giorgia Galiazzo, Fiorella Giancola, Claudio Tagliavia, Margherita De Silva, Marco Pietra, Federico Fracassi & Roberto Chiocchetti. (2020) Localization of cannabinoid and cannabinoid related receptors in the cat gastrointestinal tract. Histochemistry and Cell Biology 153:5, pages 339-356.
Crossref
Samiksha Pandey, Saima Kashif, Mina Youssef, Somia Sarwal, Hala Zraik, Ripudaman Singh & Ian H. Rutkofsky. (2020) Endocannabinoid system in irritable bowel syndrome and cannabis as a therapy. Complementary Therapies in Medicine 48, pages 102242.
Crossref
Marcella Pesce, Giuseppe Esposito & Giovanni Sarnelli. (2018) Endocannabinoids in the treatment of gastrointestinal inflammation and symptoms. Current Opinion in Pharmacology 43, pages 81-86.
Crossref
Régis Bouquié, Guillaume Deslandes, Hélène Mazaré, Marion Cogné, Julien Mahé, Matthieu Grégoire & Pascale Jolliet. (2018) Cannabis and anticancer drugs: societal usage and expected pharmacological interactions - a review. Fundamental & Clinical Pharmacology 32:5, pages 462-484.
Crossref
Nancy Maurya & Bharath Kumar Velmurugan. (2018) Therapeutic applications of cannabinoids. Chemico-Biological Interactions 293, pages 77-88.
Crossref
V.E. Tóth, Á. Fehér, J. Németh, I. Gyertyán, Z.S. Zádori & K. Gyires. (2018) Modulation of central endocannabinoid system results in gastric mucosal protection in the rat. Brain Research Bulletin 139, pages 224-234.
Crossref
Nirajan Shrestha, James S.M. Cuffe, Dana S. Hutchinson, John P. Headrick, Anthony V. Perkins, Andrew J. McAinch & Deanne H. Hryciw. (2018) Peripheral modulation of the endocannabinoid system in metabolic disease. Drug Discovery Today 23:3, pages 592-604.
Crossref
Angel Meza & Christian Lehmann. (2018) Betacaryophyllene – A phytocannabinoid as potential therapeutic modality for human sepsis?. Medical Hypotheses 110, pages 68-70.
Crossref
Anna Capasso. (2017) Do Cannabinoids Confer Neuroprotection Against Epilepsy? An Overview. The Open Neurology Journal 11:1, pages 61-73.
Crossref
Pier Vincenzo Piazza, Daniela Cota & Giovanni Marsicano. (2017) The CB1 Receptor as the Cornerstone of Exostasis. Neuron 93:6, pages 1252-1274.
Crossref
Mustafa A. Karwad, Tara Macpherson, Bo Wang, Elena Theophilidou, Sarir Sarmad, David A. Barrett, Michael Larvin, Karen L. Wright, Jonathan N. Lund & Saoirse E. O'Sullivan. (2016) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα . The FASEB Journal 31:2, pages 469-481.
Crossref
G. Vera, J. Fichna & R. Abalo. 2017. Handbook of Cannabis and Related Pathologies. Handbook of Cannabis and Related Pathologies 947 957 .
Ethan B. Russo. (2016) Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes. Cannabis and Cannabinoid Research 1:1, pages 154-165.
Crossref
Valeria Katchan, Paula David & Yehuda Shoenfeld. (2016) Cannabinoids and autoimmune diseases: A systematic review. Autoimmunity Reviews 15:6, pages 513-528.
Crossref
LING CHEN, HUIXIA CHEN, YANTING LI, LEI LI, YAN QIU & JIE REN. (2015) Endocannabinoid and ceramide levels are altered in patients with colorectal cancer. Oncology Reports 34:1, pages 447-454.
Crossref
Mark E Gerich, Robert W Isfort, Bryan Brimhall & Corey A Siegel. (2015) Medical Marijuana for Digestive Disorders: High Time to Prescribe?. American Journal of Gastroenterology 110:2, pages 208-214.
Crossref
Hesham Khairy & Wael E. Houssen. (2010) Inactivation of Anandamide Signaling: A Continuing Debate. Pharmaceuticals 3:11, pages 3355-3370.
Crossref
Karen C. Weber, Emmanuela F. De Lima, Paula H. De Mello, Albérico B. F. Da Silva & Káthia M. Honório. (2010) Research Article: Insights into the Molecular Requirements for the Anti-obesity Activity of a Series of CB1 Ligands. Chemical Biology & Drug Design 76:4, pages 320-329.
Crossref
Lei Shen, Xiao-jun Yang, Wei Qian & Xiao-hua Hou. (2010) The Role of Peripheral Cannabinoid Receptors Type 1 in Rats With Visceral Hypersensitivity Induced by Chronic Restraint Stress. Journal of Neurogastroenterology and Motility 16:3, pages 281-290.
Crossref
Soheil Sadri, Farideh Bahrami, Mozafar Khazaei, Mansoureh Hashemi & Alireza Asgari. (2010) Cannabinoid Receptor Agonist WIN-55,212-2 Protects Differentiated PC12 Cells From Organophosphorus- Induced Apoptosis. International Journal of Toxicology 29:2, pages 201-208.
Crossref
Orazio Mazzoni, Maria V. Diurno, Antonio M. di Bosco, Ettore Novellino, Paolo Grieco, Giovanni Esposito, Alessia Bertamino, Antonio Calignano & Roberto Russo. (2010) Synthesis and Pharmacological Evaluation of Analogs of Indole-Based Cannabimimetic Agents. Chemical Biology & Drug Design 75:1, pages 106-114.
Crossref
M. STORR, D. EMMERDINGER, J. DIEGELMANN, B. YÜCE, S. PFENNIG, T. OCHSENKÜHN, B. GÖKE, P. LOHSE & S. BRAND. (2009) The role of fatty acid hydrolase gene variants in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics 29:5, pages 542-551.
Crossref
Simona Pisanti, Anna Maria Malfitano, Claudia Grimaldi, Antonietta Santoro, Patrizia Gazzerro, Chiara Laezza & Maurizio Bifulco. (2009) Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. Best Practice & Research Clinical Endocrinology & Metabolism 23:1, pages 117-131.
Crossref
Meliha Karsak, Itai Bab & Andreas Zimmer. 2009. The Cannabinoid Receptors. The Cannabinoid Receptors 309 326 .
Scott D Smid. (2008) GASTROINTESTINAL ENDOCANNABINOID SYSTEM: MULTIFACETED ROLES IN THE HEALTHY AND INFLAMED INTESTINE. Clinical and Experimental Pharmacology and Physiology 35:11, pages 1383-1387.
Crossref
Ekaterina A. Placzek, Yasuo Okamoto, Natsuo Ueda & Eric L. Barker. (2008) Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. Journal of Neurochemistry.
Crossref
K L Wright, M Duncan & K A Sharkey. (2008) Cannabinoid CB 2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation . British Journal of Pharmacology 153:2, pages 263-270.
Crossref
Su-Hyoun Chon, Yin Xiu Zhou, Joseph L. Dixon & Judith Storch. (2007) Intestinal Monoacylglycerol Metabolism. Journal of Biological Chemistry 282:46, pages 33346-33357.
Crossref
G J Sanger. (2007) Endocannabinoids and the gastrointestinal tract: what are the key questions?. British Journal of Pharmacology 152:5, pages 663-670.
Crossref
Barbara Costa. (2007) On the Pharmacological Properties of Δ 9 ‐Tetrahydrocannabinol (THC) . Chemistry & Biodiversity 4:8, pages 1664-1677.
Crossref
Haibin WangSudhansu K. DeyMauro Maccarrone. (2006) Jekyll and Hyde: Two Faces of Cannabinoid Signaling in Male and Female Fertility. Endocrine Reviews 27:5, pages 427-448.
Crossref
Nicholas M Hinds, Katja Ullrich & Scott D Smid. (2006) Cannabinoid 1 (CB 1 ) receptors coupled to cholinergic motorneurones inhibit neurogenic circular muscle contractility in the human colon . British Journal of Pharmacology 148:2, pages 191-199.
Crossref
Ester Fride, Tatyana Bregman & Tim C. Kirkham. (2016) Endocannabinoids and Food Intake: Newborn Suckling and Appetite Regulation in Adulthood. Experimental Biology and Medicine 230:4, pages 225-234.
Crossref
Luciano De Petrocellis, Maurizio Bifulco, Alessia Ligresti & Vincenzo Di Marzo. 2005. Cannabinoids as Therapeutics. Cannabinoids as Therapeutics 165 181 .
A. A. Izzo & A. A. Coutts. 2005. Cannabinoids. Cannabinoids 573 598 .
Vincenzo Di Marzo, Maurizio Bifulco & Luciano De Petrocellis. (2004) The endocannabinoid system and its therapeutic exploitation. Nature Reviews Drug Discovery 3:9, pages 771-784.
Crossref
Angelo A Izzo. (2004) Cannabinoids and intestinal motility: welcome to CB 2 receptors . British Journal of Pharmacology 142:8, pages 1201-1202.
Crossref
Wallace K. MacNaughton, Marja D. Van Sickle, Catherine M. Keenan, Kelly Cushing, Ken Mackie & Keith A. Sharkey. (2004) Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves. American Journal of Physiology-Gastrointestinal and Liver Physiology 286:5, pages G863-G871.
Crossref
Pamela J Hornby & Stephen M Prouty. (2004) Involvement of cannabinoid receptors in gut motility and visceral perception. British Journal of Pharmacology 141:8, pages 1335-1345.
Crossref
M. Storr, A. Sibaev, G. Marsicano, B. Lutz, V. Schusdziarra, J.-P. Timmermans & H. D. Allescher. (2004) Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon. American Journal of Physiology-Gastrointestinal and Liver Physiology 286:1, pages G110-G117.
Crossref
Manuel Guzmán. (2003) Cannabinoids: potential anticancer agents. Nature Reviews Cancer 3:10, pages 745-755.
Crossref
David Royston & Felicia Cox. (2003) Anaesthesia: the patient's point of view. The Lancet 362:9396, pages 1648-1658.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.