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Expert Opinion on Investigational Drugs Volume 12, 2003 - Issue 4
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Review

The use of antioxidants in Friedreich’s ataxia treatment

Pierre Rustin INSERM U393, Tour Lavoisier, Hôpital des Enfants-Malades, 149, rue de Sèvres, 75743 Paris Cedex 15, France
Pages 569-575 | Published online: 02 Mar 2005

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Susan L Perlman. (2003) Spinocerebellar degeneration. Expert Opinion on Pharmacotherapy 4:10, pages 1637-1641.
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Sze-Yuen LEW, Yoon-Yen YOW, Lee-Wei LIM & Kah-Hui WONG. (2020) Antioxidant-mediated protective role of Hericium erinaceus (Bull.: Fr.) Pers. against oxidative damage in fibroblasts from Friedreich’s ataxia patient. Food Science and Technology 40:suppl 1, pages 264-272.
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Stéphane Fourcade, Isidre Ferrer & Aurora Pujol. (2015) Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration. Free Radical Biology and Medicine 88, pages 18-29.
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José Marín-GarcíaJosé Marín-García. 2013. Mitochondria and Their Role in Cardiovascular Disease. Mitochondria and Their Role in Cardiovascular Disease 431 452 .
Ruoyang Shi, Jiequn Weng, Paul Szelemej & Jiming Kong. 2012. Translational Stroke Research. Translational Stroke Research 145 174 .
Aurélien Bayot, Renata Santos, Jean-Michel Camadro & Pierre Rustin. (2011) Friedreich's ataxia: the vicious circle hypothesis revisited. BMC Medicine 9:1.
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Arnulf H. Koeppen. 2011. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders 288 298 .
Kuanyu Li, Anamika Singh, Daniel R. Crooks, Xiaoman Dai, Zhuangzhuang Cong, Liang Pan, Dung Ha & Tracey A. Rouault. (2010) Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2. PLoS ONE 5:8, pages e12286.
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Vincent Paupe, Emmanuel P. Dassa, Sergio Goncalves, Françoise Auchère, Maria Lönn, Arne Holmgren & Pierre Rustin. (2009) Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia. PLoS ONE 4:1, pages e4253.
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Amy Y. Tsou, Lisa S. Friedman, Robert B. Wilson & David R. Lynch. (2009) Pharmacotherapy for Friedreich Ataxia. CNS Drugs 23:3, pages 213-223.
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Sergio Goncalves, Vincent Paupe, Emmanuel P Dassa & Pierre Rustin. (2008) Deferiprone targets aconitase: Implication for Friedreich's ataxia treatment. BMC Neurology 8:1.
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Jörg B. Schulz. (2007) Hereditäre BewegungsstörungenHereditary movement disorders. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 50:12, pages 1524-1530.
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Matthias L. Jauslin, Silvia Vertuani, Elisa Durini, Lisa Buzzoni, Nunzia Ciliberti, Sara Verdecchia, Paola Palozza, Thomas Meier & Stefano Manfredini. (2007) Protective effects of Fe-Aox29, a novel antioxidant derived from a molecular combination of Idebenone and vitamin E, in immortalized fibroblasts and fibroblasts from patients with Friedreich Ataxia. Molecular and Cellular Biochemistry 302:1-2, pages 79-85.
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J. Finsterer. (2007) Genetic, pathogenetic, and phenotypic implications of the mitochondrial A3243G tRNALeu(UUR) mutation. Acta Neurologica Scandinavica 116:1, pages 1-14.
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A. Joyce Young, Stephanie Johnson, David C. Steffens & P. Murali Doraiswamy. (2014) Coenzyme Q10: A Review of Its Promise as a Neuroprotectant . CNS Spectrums 12:1, pages 62-68.
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H. Puccio. 2007. Conditional Mutagenesis: An Approach to Disease Models. Conditional Mutagenesis: An Approach to Disease Models 365 375 .
Eleonora NapoliFranco TaroniGino A. Cortopassi. (2006) Frataxin, Iron–Sulfur Clusters, Heme, ROS, and Aging. Antioxidants & Redox Signaling 8:3-4, pages 506-516.
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HÉLÈNE PUCCIO. 2006. Genetic Instabilities and Neurological Diseases. Genetic Instabilities and Neurological Diseases 321 326 .
Karen Usdin & Michael Fry. 2006. Human Nucleotide Expansion Disorders. Human Nucleotide Expansion Disorders 279 287 .
A.M. Fernandez, E.M. Carro, C. Lopez-Lopez & I. Torres-Aleman. (2005) Insulin-like growth factor I treatment for cerebellar ataxia: Addressing a common pathway in the pathological cascade?. Brain Research Reviews 50:1, pages 134-141.
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Guido Kroemer & Seamus J Martin. (2005) Caspase-independent cell death. Nature Medicine 11:7, pages 725-730.
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HYMAN M. SCHIPPER. (2004) Redox Neurology: Visions of an Emerging Subspecialty. Annals of the New York Academy of Sciences 1012:1, pages 342-355.
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