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Review

Clinical status of agents being developed for leishmaniasis

Pages 1337-1346 | Published online: 28 Oct 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Neena Goyal. (2013) Novel approaches for the identification of inhibitors of leishmanial dipeptidylcarboxypeptidase. Expert Opinion on Drug Discovery 8:9, pages 1127-1134.
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Guilherme Carneiro, Marta Gontijo Aguiar, Ana Paula Fernandes & Lucas Antônio Miranda Ferreira. (2012) Drug delivery systems for the topical treatment of cutaneous leishmaniasis . Expert Opinion on Drug Delivery 9:9, pages 1083-1097.
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Sunandini Chandra, Dipali Ruhela, Anindita Deb & Ram A Vishwakarma. (2010) Glycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery. Expert Opinion on Therapeutic Targets 14:7, pages 739-757.
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Margriet den Boer & Robert N Davidson. (2006) Treatment options for visceral leishmaniasis. Expert Review of Anti-infective Therapy 4:2, pages 187-197.
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Ermin Schadich, Susanne Nylén, Soňa Gurská, Jana Kotulová, Sergey Andronati, Victor Pavlovsky, Svetlana Soboleva, Pavel Polishchuk, Marián Hajdúch & Petr Džubák. (2022) Activity of 1-aryl-4-(naphthalimidoalkyl) piperazine derivatives against Leishmania major and Leishmania mexicana. Parasitology International 91, pages 102647.
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Regina Maia de Souza, Roberta Cristina Ruedas Martins, Lucas Augusto Moyses Franco, Felipe Francisco Tuon, Isael Gomes de Oliveira Junior, Camila Alves Maia da Silva, Rui Imamura & Valdir Sabbaga Amato. (2022) Identification of Leishmania species by next generation sequencing of hsp70 gene. Molecular and Cellular Probes 61, pages 101791.
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Viviane Pereira, Neuza Biguinati de Barros, Sharon Rose Aragão Macedo, Amália dos Santos Ferreira, Luiz Alberto Kanis & Roberto Nicolete. (2019) Drug-containing hydrophobic dressings as a topical experimental therapy for cutaneous leishmaniasis. Journal of Parasitic Diseases 44:1, pages 79-87.
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Luiz C. S. Pinheiro, Maria de Lourdes G. Ferreira, Flávia F. Silveira, Lívia M. Feitosa & Nubia Boechat. (2019) Synthetic compounds with sulfonamide moiety against Leishmaniasis: an overview. Medicinal Chemistry Research 28:11, pages 1807-1817.
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Elias Ferreira Sabiá Júnior, Luis Felipe Santos Menezes, Israel Flor Silva de Araújo & Elisabeth Ferroni Schwartz. (2019) Natural Occurrence in Venomous Arthropods of Antimicrobial Peptides Active against Protozoan Parasites. Toxins 11:10, pages 563.
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Eliane de Morais-Teixeira, Ana Rabello & Marta Marques Gontijo Aguiar. (2019) In vitro activity and in vivo efficacy of fexinidazole against New World Leishmania species. Journal of Antimicrobial Chemotherapy 74:8, pages 2318-2325.
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Emilia Díaz & Alicia Ponte-Sucre. 2018. Drug Resistance in Leishmania Parasites. Drug Resistance in Leishmania Parasites 1 16 .
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Eliane de Morais-Teixeira, Marta Gontijo Aguiar, Bruna Soares de Souza Lima, Lucas Antônio Miranda Ferreira & Ana Rabello. (2015) Combined suboptimal schedules of topical paromomycin, meglumine antimoniate and miltefosine to treat experimental infection caused by Leishmania ( Viannia ) braziliensis . Journal of Antimicrobial Chemotherapy, pages dkv254.
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Behrouz Ezatpour, Ebrahim Saedi Dezaki, Hossein Mahmoudvand, Mojgan Azadpour & Fatemeh Ezzatkhah. (2015) In Vitro and In Vivo Antileishmanial Effects of Pistacia khinjuk against Leishmania tropica and Leishmania major . Evidence-Based Complementary and Alternative Medicine 2015, pages 1-6.
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Denis Zofou, Raymond B Nyasa, Dickson S Nsagha, Fidele Ntie-Kang, Henry D Meriki, Jules Clement N Assob & Victor Kuete. (2014) Control of malaria and other vector-borne protozoan diseases in the tropics: enduring challenges despite considerable progress and achievements. Infectious Diseases of Poverty 3:1.
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Ifedayo Victor Ogungbe, Joseph D Ng & William N Setzer. (2013) Interactions of antiparasitic alkaloids with Leishmania protein targets: a molecular docking analysis . Future Medicinal Chemistry 5:15, pages 1777-1799.
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Christopher F. Prada, Raquel ?lvarez-Velilla, Rafael Bala?a-Fouce, Carlos Prieto, Estefania Calvo-?lvarez, Jose Miguel Escudero-Mart?nez, Jos? Mar?a Requena, C?sar Ord??ez, Alessandro Desideri, Yolanda P?rez-Pertejo & Rosa M. Reguera. (2013) Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect. Biochemical Pharmacology 85:10, pages 1433-1440.
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A. Ponte-Sucre. 2013. Drug Resistance in Leishmania Parasites. Drug Resistance in Leishmania Parasites 1 12 .
Bhaskar, Neeti Kumari & Neena Goyal. (2012) Cloning, characterization and sub-cellular localization of gamma subunit of T-complex protein-1 (chaperonin) from Leishmania donovani. Biochemical and Biophysical Research Communications 429:1-2, pages 70-74.
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Christopher F. Prada, Raquel Álvarez-Velilla, Rosario Diaz-González, Carlos Prieto, Yolanda Pérez-Pertejo, Rafael Balaña-Fouce & Rosa M. Reguera. (2012) A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity. Biochimica et Biophysica Acta (BBA) - General Subjects 1820:12, pages 2062-2071.
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Diogo G. Valadares, Mariana C. Duarte, Laura Ramírez, Miguel A. Chávez-Fumagalli, Vivian T. Martins, Lourena E. Costa, Paula S. Lage, Tatiana G. Ribeiro, Rachel O. Castilho, Ana Paula Fernandes, Wiliam C.B. Régis, Manuel Soto, Carlos A.P. Tavares & Eduardo A.F. Coelho. (2012) Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis. Experimental Parasitology 132:2, pages 228-236.
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M. G. Aguiar, D. L. Silva, F. A. Nunan, E. A. Nunan, A. P. Fernandes & L. A. M. Ferreira. (2009) Combined topical paromomycin and oral miltefosine treatment of mice experimentally infected with Leishmania (Leishmania) major leads to reduction in both lesion size and systemic parasite burdens. Journal of Antimicrobial Chemotherapy 64:6, pages 1234-1240.
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