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Review

New advances in antibiotic development and discovery

Pages 117-134 | Published online: 22 Apr 2005

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Zhi-Xiong Ruan, De-Sheng Huangfu, Xing-Jun Xu, Ping-Hua Sun & Wei-Min Chen. (2013) 3D-QSAR and molecular docking for the discovery of ketolide derivatives. Expert Opinion on Drug Discovery 8:4, pages 427-444.
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Gordon S Lynch. (2008) Update on emerging drugs for sarcopenia – age-related muscle wasting. Expert Opinion on Emerging Drugs 13:4, pages 655-673.
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Urs A Ochsner, Xicheng Sun, Thale Jarvis, Ian Critchley & Nebojsa Janjic. (2007) Aminoacyl-tRNA synthetases: essential and still promising targets for new anti-infective agents. Expert Opinion on Investigational Drugs 16:5, pages 573-593.
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Vipin Chandra Kalia, Asha Rani, Sadhana Lal, Simrita Cheema & C P Raut. (2007) Combing databases reveals potential antibiotic producers. Expert Opinion on Drug Discovery 2:2, pages 211-224.
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Garyphallia Poulakou & Helen Giamarellou. (2007) Investigational treatments for postoperative surgical site infections. Expert Opinion on Investigational Drugs 16:2, pages 137-155.
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Liangsu Wang & John F Barrett. (2006) Pharmacoeconomics of treatment with the newer anti-Gram-positive agents. Expert Opinion on Pharmacotherapy 7:7, pages 885-897.
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Valentina Molteni & Andreas Kreusch. (2005) Peptide deformylase inhibitors: a survey of the patent literature. Expert Opinion on Therapeutic Patents 15:10, pages 1423-1437.
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Thomas J Dougherty & Thomas V Magee. (2005) Novel antibacterial compounds addressing resistance: patent disclosures 2002 – 2005. Expert Opinion on Therapeutic Patents 15:10, pages 1409-1421.
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Anastasia Skvortsova, Andrii Trelin, Pavel Kriz, Roman Elashnikov, Barbora Vokata, Pavel Ulbrich, Alexandra Pershina, Vaclav Svorcik, Olga Guselnikova & Oleksiy Lyutakov. (2022) SERS and advanced chemometrics – Utilization of Siamese neural network for picomolar identification of beta-lactam antibiotics resistance gene fragment. Analytica Chimica Acta 1192, pages 339373.
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Hongzhi Xiao, Pan Sun, Jicheng Qiu, Jianzhong Wang, Lei Yan, Suxia Zhang & Xingyuan Cao. (2020) Determination of Lekethromycin, a Novel Macrolide Lactone, in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study. Molecules 25:20, pages 4676.
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Afeefah Khazi-Syed, Md Tanvir Hasan, Elizabeth Campbell, Roberto Gonzalez-Rodriguez & Anton V. Naumov. (2019) Single-Walled Carbon Nanotube-Assisted Antibiotic Delivery and Imaging in S. epidermidis Strains Addressing Antibiotic Resistance. Nanomaterials 9:12, pages 1685.
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Faris Alrumaihi, Khaled S. Allemailem, Ahmad Almatroudi, Mohammed A. Alsahli, Arif Khan & Masood A. Khan. (2019) Tinospora cordifolia Aqueous Extract Alleviates Cyclophosphamide- Induced Immune Suppression, Toxicity and Systemic Candidiasis in Immunosuppressed Mice: In vivo Study in Comparison to Antifungal Drug Fluconazole. Current Pharmaceutical Biotechnology 20:12, pages 1055-1063.
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Sultan Alsuhaibani & Masood A. Khan. (2017) Immune-Stimulatory and Therapeutic Activity of Tinospora cordifolia : Double-Edged Sword against Salmonellosis . Journal of Immunology Research 2017, pages 1-9.
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Weiling Hong, Jie Zeng & Jianping Xie. (2014) Antibiotic drugs targeting bacterial RNAs. Acta Pharmaceutica Sinica B 4:4, pages 258-265.
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Brygida Kwiatkowska, Maria Maslinska, Malgorzata Przygodzka, Joanna Dmowska-Chalaba, Justyna Dabrowska & Katarzyna Sikorska-Siudek. (2013) Immune system as a new therapeutic target for antibiotics. Advances in Bioscience and Biotechnology 04:04, pages 91-101.
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Tobias W. Giessen & Mohamed A. Marahiel. (2012) Ribosome-independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity. FEBS Letters 586:15, pages 2065-2075.
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Manjinder S. Lall, Garrett HogeTuan P. Tran, William Kissel, Sean T. Murphy, Clarke Taylor, Kim Hutchings, Brian Samas, Edmund L. Ellsworth, Timothy Curran & H. D. Hollis Showalter. (2012) Stereoselective Synthesis of ( S )-3-(Methylamino)-3-(( R )-pyrrolidin-3-yl)propanenitrile . The Journal of Organic Chemistry 77:10, pages 4732-4739.
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Brygida Kwiatkowska & Maria Maślińska. (2012) Macrolide Therapy in Chronic Inflammatory Diseases. Mediators of Inflammation 2012, pages 1-7.
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Pedro Brugarolas, Erica M. Duguid, Wen Zhang, Catherine B. Poor & Chuan He. (2011) Structural and biochemical characterization of N 5 -carboxyaminoimidazole ribonucleotide synthetase and N 5 -carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus . Acta Crystallographica Section D Biological Crystallography 67:8, pages 707-715.
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Andrea Mencarelli, Eleonora Distrutti, Barbara Renga, Sabrina Cipriani, Giuseppe Palladino, Catherine Booth, Gregory Tudor, Jan-Hinrich Guse, Ulrike Hahn, Micheal Burnet & Stefano Fiorucci. (2011) Development of non-antibiotic macrolide that corrects inflammation-driven immune dysfunction in models of inflammatory bowel diseases and arthritis. European Journal of Pharmacology 665:1-3, pages 29-39.
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Mukul Sharma, Penny Joshi, Nitin Kumar, Seema Joshi, Rajesh K. Rohilla, Nilanjan Roy & Diwan S. Rawat. (2011) Synthesis, antimicrobial activity and structure–activity relationship study of N,N-dibenzyl-cyclohexane-1,2-diamine derivatives. European Journal of Medicinal Chemistry 46:2, pages 480-487.
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Anil K Agarwal & Colin W. G. Fishwick. (2010) Structure-based design of anti-infectives. Annals of the New York Academy of Sciences 1213:1, pages 20-45.
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Dražen Pavlović, Andrea Fajdetić & Stjepan Mutak. (2010) Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials. Bioorganic & Medicinal Chemistry 18:24, pages 8566-8582.
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Chambers C. Hughes & William Fenical. (2010) Antibacterials from the Sea. Chemistry – A European Journal 16:42, pages 12512-12525.
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Dražen Pavlović & Stjepan Mutak. (2010) Synthesis and Structure−Activity Relationships of Novel 8a-Aza-8a-homoerythromycin A Ketolides. Journal of Medicinal Chemistry 53:15, pages 5868-5880.
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James B. Thoden, Hazel M. Holden, Hanumantharao Paritala & Steven M. Firestine. (2010) Structural and Functional Studies of Aspergillus clavatus N 5 -Carboxyaminoimidazole Ribonucleotide Synthetase, . Biochemistry 49:4, pages 752-760.
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Deepak Kumar, Seema Joshi, Rajesh K. Rohilla, Nilanjan Roy & Diwan S. Rawat. (2010) Synthesis and antibacterial activity of benzyl-[3-(benzylamino-methyl)-cyclohexylmethyl]-amine derivatives. Bioorganic & Medicinal Chemistry Letters 20:3, pages 893-895.
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Sunil K. Vooturi & Steven M. Firestine. (2009) Solution-Phase Parallel Synthesis of Novel Membrane-Targeted Antibiotics. Journal of Combinatorial Chemistry 12:1, pages 151-160.
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Hyung-Moo Jung, Marimuthu Jeya, Sang-Yong Kim, Hee-Jung Moon, Raushan Kumar Singh, Ye-Wang Zhang & Jung-Kul Lee. (2009) Biosynthesis, biotechnological production, and application of teicoplanin: current state and perspectives. Applied Microbiology and Biotechnology 84:3, pages 417-428.
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Sunil K. Vooturi, Chrissy M. Cheung, Michael J. Rybak & Steven M. Firestine. (2009) Design, Synthesis, and Structure−Activity Relationships of Benzophenone-Based Tetraamides as Novel Antibacterial Agents. Journal of Medicinal Chemistry 52:16, pages 5020-5031.
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Steven M. Firestine, Hanumantharao Paritala, Jane E. Mcdonnell, James B. Thoden & Hazel M. Holden. (2009) Identification of inhibitors of N5-carboxyaminoimidazole ribonucleotide synthetase by high-throughput screening. Bioorganic & Medicinal Chemistry 17:9, pages 3317-3323.
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Richard H Baltz. (2006) Molecular engineering approaches to peptide, polyketide and other antibiotics. Nature Biotechnology 24:12, pages 1533-1540.
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G. H. Talbot, J. Bradley, J. E. Edwards, D. Gilbert, M. Scheld & J. G. Bartlett. (2006) Bad Bugs Need Drugs: An Update on the Development Pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clinical Infectious Diseases 42:5, pages 657-668.
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Mark S. Butler & Antony D. Buss. (2006) Natural products ? The future scaffolds for novel antibiotics?. Biochemical Pharmacology 71:7, pages 919-929.
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Stefan Pelzer & Agnieszka Dziarnowski. (2006) Sulfation: A New Biocombinatorial Tool. Chemistry & Biology 13:2, pages 113-114.
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Kevin R Foster & Hajo Grundmann. (2006) Do We Need to Put Society First? The Potential for Tragedy in Antimicrobial Resistance. PLoS Medicine 3:2, pages e29.
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Shridhar Hegde & Michelle Schmidt. 2006. Annual Reports in Medicinal Chemistry Volume 41. Annual Reports in Medicinal Chemistry Volume 41 439 477 .
Falko Wolter, Sebastian Schoof & Roderich D. Süssmuth. 2006. Glycopeptides and Glycoproteins. Glycopeptides and Glycoproteins 143 185 .

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