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Drug Evaluation

Lasofoxifene: a third-generation selective estrogen receptor modulator for the prevention and treatment of osteoporosis

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Pages 1091-1103 | Published online: 17 Aug 2006

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Andreas Fontalis, Eustathios Kenanidis, Rafail Angelos Kotronias, Afroditi Papachristou, Panagiotis Anagnostis, Michael Potoupnis & Eleftherios Tsiridis. (2019) Current and emerging osteoporosis pharmacotherapy for women: state of the art therapies for preventing bone loss. Expert Opinion on Pharmacotherapy 20:9, pages 1123-1134.
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Miriam Carr, Andrew J. S. Knox, David G. Lloyd, Daniela M. Zisterer & Mary J. Meegan. (2016) Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup3, pages 117-130.
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Pailla Umareddy & Veera Reddy Arava. (2016) Total synthesis of lasofoxifene and nafoxidine. Synthetic Communications 46:4, pages 309-313.
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Luigi Gennari, Daniela Merlotti, Konstantinos Stolakis & Ranuccio Nuti. (2012) Pharmacokinetic evaluation of toremifene and its clinical implications for the treatment of osteoporosis. Expert Opinion on Drug Metabolism & Toxicology 8:4, pages 505-513.
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Luigi Gennari, Daniela Merlotti & Ranuccio Nuti. (2010) Selective estrogen receptor modulator (SERM) for the treatment of osteoporosis in postmenopausal women: focus on lasofoxifene. Clinical Interventions in Aging 5, pages 19-29.
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Luigi Gennari, Daniela Merlotti & Ranuccio Nuti. (2009) Lasofoxifene: a new-generation SERM for the treatment of postmenopausal osteoporosis. Expert Review of Obstetrics & Gynecology 4:6, pages 607-617.
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Luigi Gennari. (2009) Lasofoxifene, a new selective estrogen receptor modulator for the treatment of osteoporosis and vaginal atrophy. Expert Opinion on Pharmacotherapy 10:13, pages 2209-2220.
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Chang Bai, Osvaldo Flores & Azriel Schmidt. (2007) Opportunities for development of novel therapies targeting steroid hormone receptors. Expert Opinion on Drug Discovery 2:5, pages 725-737.
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Carin C.C. Johansson Seechurn, Ivana Gazić Smilović, Thomas Colacot, Antonio Zanotti-Gerosa & Zdenko Časar. (2018) Development of concise two-step catalytic approach towards lasofoxifene precursor nafoxidine. Bioorganic & Medicinal Chemistry 26:9, pages 2691-2697.
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