Citations (47)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Qiong Xie, Zhaoxi Zheng, Biyun Shao, Wei Fu, Zheng Xia, Wei Li, Jian Sun, Wei Zheng, Weiwei Zhang, Wei Sheng, Qihong Zhang, Hongzhuan Chen, Hao Wang & Zhuibai Qiu. (2017) Pharmacophore-based design and discovery of (−)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 659-671.
Read now
Read now
Daniela Galimberti & Elio Scarpini. (2016) Old and new acetylcholinesterase inhibitors for Alzheimer’s disease. Expert Opinion on Investigational Drugs 25:10, pages 1181-1187.
Read now
Read now
Altaf S Darvesh, Richard T Carroll, Werner J Geldenhuys, Gary A Gudelsky, Jochen Klein, Charles K Meshul & Cornelis J Van der Schyf. (2011)
In vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery. Expert Opinion on Drug Discovery 6:2, pages 109-127.
Read now
Read now
Jerry J Buccafusco. (2009) Emerging cognitive enhancing drugs. Expert Opinion on Emerging Drugs 14:4, pages 577-589.
Read now
Read now
Articles from other publishers (43)
Hai Ren, Rui-An Wang, Jun Shi, Jun-Rong Song, Wei Wu, Qin Chi & Ni Zhang. (2023) Electrochemical bromocyclization enables 3,5-diversification of heterocyclic indolines. Organic & Biomolecular Chemistry 21:36, pages 7290-7294.
Crossref
Crossref
Brian RobinsonBrian Robinson. 2023. The Calabar Bean and its Alkaloids. The Calabar Bean and its Alkaloids
25
122
.
Brian RobinsonBrian Robinson. 2023. The Calabar Bean and its Alkaloids. The Calabar Bean and its Alkaloids
169
224
.
Ana Matošević, Anamarija Knežević, Antonio Zandona, Nikola Maraković, Zrinka Kovarik & Anita Bosak. (2022) Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease. Pharmaceuticals 15:10, pages 1220.
Crossref
Crossref
Andreea L. Turcu, Júlia Companys-Alemany, Matthew B. Phillips, Dhilon S. Patel, Christian Griñán-Ferré, M. Isabel Loza, José M. Brea, Belén Pérez, David Soto, Francesc X. Sureda, Maria G. Kurnikova, Jon W. Johnson, Mercè Pallàs & Santiago Vázquez. (2022) Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease. European Journal of Medicinal Chemistry 236, pages 114354.
Crossref
Crossref
Ankit Jana, Arkadyuti Bhattacharjee, Sabya Sachi Das, Avani Srivastava, Akshpita Choudhury, Rahul Bhattacharjee, Swagata De, Asma Perveen, Danish Iqbal, Piyush Kumar Gupta, Saurabh Kumar Jha, Shreesh Ojha, Sandeep Kumar Singh, Janne Ruokolainen, Niraj Kumar Jha, Kavindra Kumar Kesari & Ghulam Md Ashraf. (2022) Molecular Insights into Therapeutic Potentials of Hybrid Compounds Targeting Alzheimer’s Disease. Molecular Neurobiology 59:6, pages 3512-3528.
Crossref
Crossref
Julien Delrieu & Bruno Vellas. 2022. Pathy's Principles and Practice of Geriatric Medicine. Pathy's Principles and Practice of Geriatric Medicine
843
859
.
Esra Küpeli Akkol, Gökçe Şeker Karatoprak, Elif Carpar, Yaseen Hussain, Haroon Khan & Michael Aschner. (2022) Effects of Natural Products on Neuromuscular Junction. Current Neuropharmacology 20:3, pages 594-610.
Crossref
Crossref
Sidra Batool, Tiyyaba Furqan, Muhammad Sibte Hasan Mahmood, David Tweedie, Mohammad A. Kamal & Nigel H. Greig. (2022)
In Silico
and
Ex Vivo
Analyses of the Inhibitory Action of the Alzheimer Drug Posiphen and Primary Metabolites with Human Acetyl- and Butyrylcholinesterase Enzymes
. ACS Pharmacology & Translational Science 5:2, pages 70-79.
Crossref
Crossref
Jia Zhou, Zi-Hao Li, Le Wang, Jun-Chen Kang, Xun-Hui Wang & Shu-Yu Zhang. (2021)
Base-Promoted Cobalt-Catalyzed Regio- and Enantioselective
para
-Friedel–Crafts Alkylation of Aniline Derivatives
. Organic Letters 23:24, pages 9353-9359.
Crossref
Crossref
Erma Fatiha Muhammad, Ashutosh Kumar, Habibah A. Wahab & Kam Y.J. Zhang. (2021) Identification of 1,2,4‐Triazolylthioethanone Scaffold for the Design of New Acetylcholinesterase Inhibitors. Molecular Informatics 40:8, pages 2100020.
Crossref
Crossref
Mohammad Shahrivar‐Gargari, Maryam Hamzeh‐Mivehroud, Salar Hemmati, Javid S. Mojarrad, Tuba Tüylü Küçükkılınç, Beyza Ayazgök & Siavoush Dastmalchi. (2021) Hybridization‐based design of novel anticholinesterase indanone–carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies. Archiv der Pharmazie 354:7.
Crossref
Crossref
Immacolata Vecchio, Luca Sorrentino, Annamaria Paoletti, Rosario Marra & Mariamena Arbitrio. (2021) The State of The Art on Acetylcholinesterase Inhibitors in the Treatment of Alzheimer’s Disease. Journal of Central Nervous System Disease 13, pages 117957352110291.
Crossref
Crossref
Vipul Chaudhary, Ashwini Kumar Nigam, Ashutosh Paliwal, Manoj Kumar Singh, Jalaj Kumar Gour & Vimlendu Bhushan Sinha. 2021. Naturally Occurring Chemicals Against Alzheimer's Disease. Naturally Occurring Chemicals Against Alzheimer's Disease
65
82
.
Tina Bilousova, Bryan J. Simmons, Rachel R. Knapp, Chris J. Elias, Jesus Campagna, Mikhail Melnik, Sujyoti Chandra, Samantha Focht, Chunni Zhu, Kanagasabai Vadivel, Barbara Jagodzinska, Whitaker Cohn, Patricia Spilman, Karen H. Gylys, Neil K. Garg & Varghese John. (2020) Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease. ACS Chemical Biology 15:6, pages 1671-1684.
Crossref
Crossref
Nigel H. Greig, Daniela Lecca, Shih‐Chang Hsueh, Carlos Nogueras‐Ortiz, Dimitrios Kapogiannis, David Tweedie, Elliot J. Glotfelty, Robert E. Becker, Yung‐Hsiao Chiang & Barry J. Hoffer. (2019) (−)‐Phenserine tartrate (PhenT) as a treatment for traumatic brain injury. CNS Neuroscience & Therapeutics 26:6, pages 636-649.
Crossref
Crossref
Seong-Jin Yu, Kuo-Jen Wu, Eunkyung Bae, Yu –Syuan Wang, Chia-Wen Chiang, Li-Wei Kuo, Brandon K. Harvey, Nigel H. Greig & Yun Wang. (2020) Post-treatment with Posiphen reduces endoplasmic reticulum stress and neurodegeneration in stroke brain. iScience, pages 100866.
Crossref
Crossref
Gabriela Dumitrita Stanciu, Andrei Luca, Razvan Nicolae Rusu, Veronica Bild, Sorin Ioan Beschea Chiriac, Carmen Solcan, Walther Bild & Daniela Carmen Ababei. (2019) Alzheimer’s Disease Pharmacotherapy in Relation to Cholinergic System Involvement. Biomolecules 10:1, pages 40.
Crossref
Crossref
Shih-Chang Hsueh, Daniela Lecca, Nigel H. Greig, Jia-Yi Wang, Warren Selman, Barry J. Hoffer, Jonathan P. Miller & Yung-Hsiao Chiang. (2019) (-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice. Cell Transplantation 28:9-10, pages 1183-1196.
Crossref
Crossref
Adebayo A Adeniyi & Jeanet Conradie. (2019) Computational insight into the anticholinesterase activities and electronic properties of physostigmine analogs. Future Medicinal Chemistry 11:15, pages 1907-1928.
Crossref
Crossref
Kamlesh Sharma. (2019) Cholinesterase inhibitors as Alzheimer's therapeutics (Review). Molecular Medicine Reports.
Crossref
Crossref
Alexander Tuan-Huy Duong, Bryan J. Simmons, Mohammad Parvez Alam, Jesus Campagna, Neil K. Garg & Varghese John. (2019) Synthesis of fused indolines by interrupted Fischer indolization in a microfluidic reactor. Tetrahedron Letters 60:3, pages 322-326.
Crossref
Crossref
Atish Kumar Sahoo, Jagnehswar Dandapat, Umesh Chandra Dash & Satish Kanhar. (2018) Features and outcomes of drugs for combination therapy as multi-targets strategy to combat Alzheimer's disease. Journal of Ethnopharmacology 215, pages 42-73.
Crossref
Crossref
Cheng-Fu Chang, Jing-Huei Lai, John Chung-Che Wu, Nigel H. Greig, Robert E. Becker, Yu Luo, Yen-Hua Chen, Shuo-Jhen Kang, Yung-Hsiao Chiang & Kai-Yun Chen. (2017) (−)-Phenserine inhibits neuronal apoptosis following ischemia/reperfusion injury. Brain Research 1677, pages 118-128.
Crossref
Crossref
Taoyi Yang, Ting Xiao, Qi Sun & Kewei Wang. (2017) The current agonists and positive allosteric modulators of α 7 nAChR for CNS indications in clinical trials. Acta Pharmaceutica Sinica B 7:6, pages 611-622.
Crossref
Crossref
Corien de Graaff, Lisa Bensch, Sjoerd J. Boersma, Răzvan C. Cioc, Matthijs J. van Lint, Elwin Janssen, Nicholas J. Turner, Romano V. A. Orru & Eelco Ruijter. (2015) Asymmetric Synthesis of Tetracyclic Pyrroloindolines and Constrained Tryptamines by a Switchable Cascade Reaction. Angewandte Chemie International Edition 54:47, pages 14133-14136.
Crossref
Crossref
Corien de Graaff, Lisa Bensch, Sjoerd J. Boersma, Răzvan C. Cioc, Matthijs J. van Lint, Elwin Janssen, Nicholas J. Turner, Romano V. A. Orru & Eelco Ruijter. (2015) Asymmetric Synthesis of Tetracyclic Pyrroloindolines and Constrained Tryptamines by a Switchable Cascade Reaction. Angewandte Chemie 127:47, pages 14339-14342.
Crossref
Crossref
Amedeo Amedei & Elena Niccolai. 2014. Natural Products Analysis. Natural Products Analysis
43
113
.
Ying Xie, Pan Jiang, Xinxing Ge, Hao Wang, Biyun Shao, Qiong Xie, Zhuibai Qiu & Hongzhuan Chen. (2014) Determination of a novel carbamate AChE inhibitor meserine in mouse plasma, brain and rat plasma by LC–MS/MS: Application to pharmacokinetic study after intravenous and subcutaneous administration. Journal of Pharmaceutical and Biomedical Analysis 96, pages 156-161.
Crossref
Crossref
Zhaoxi Zheng, Yabin Tang, Haoyu Lv, Jianrong Xu, Hengyi Zhao, Qiong Xie, Zhuibai Qiu, Hongzhuan Chen & Hao Wang. (2014) Determination of Meserine, a new candidate for Alzheimer’s disease in mice brain by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic and tissue distribution study. Analytical and Bioanalytical Chemistry 406:14, pages 3451-3458.
Crossref
Crossref
Paul J. Pistell, Edward L. Spangler, Bennett Kelly-Bell, Marshall G. Miller, Rafael de Cabo & Donald K. Ingram. (2012) Age-associated learning and memory deficits in two mouse versions of the stone T-maze. Neurobiology of Aging 33:10, pages 2431-2439.
Crossref
Crossref
Julien Delrieu, Antoine Piau & Bruno Vellas. 2012. Pathy's Principles and Practice of Geriatric Medicine. Pathy's Principles and Practice of Geriatric Medicine
923
941
.
Sohan Mikkilineni, Ippolita Cantuti-Castelvetri, Catherine M. Cahill, Amelie Balliedier, Nigel H. Greig & Jack T. Rogers. (2012)
The Anticholinesterase Phenserine and Its Enantiomer Posiphen as 5
′
Untranslated-Region-Directed Translation Blockers of the Parkinson’s Alpha Synuclein Expression
. Parkinson's Disease 2012, pages 1-13.
Crossref
Crossref
Keri Martinowich, Robert J. Schloesser, Yuan Lu, Dennisse V. Jimenez, Daniel Paredes, Joshua S. Greene, Nigel H. Greig, Husseini K. Manji & Bai Lu. (2012) Roles of p75NTR, Long-Term Depression, and Cholinergic Transmission in Anxiety and Acute Stress Coping. Biological Psychiatry 71:1, pages 75-83.
Crossref
Crossref
Sazal Patyar, Ajay Prakash & Bikash Medhi. (2011) Dual inhibition: a novel promising pharmacological approach for different disease conditions. Journal of Pharmacy and Pharmacology 63:4, pages 459-471.
Crossref
Crossref
Antoine Piau, F. Nourhashémi, C. Hein, C. Caillaud & B. Vellas. (2011) Progress in the development of new drugs in Alzheimer’s disease. The journal of nutrition, health & aging 15:1, pages 45-57.
Crossref
Crossref
Qian-sheng Yu, Harold W. Holloway, Weiming Luo, Debomoy K. Lahiri, Arnold Brossi & Nigel H. Greig. (2010) Long-acting anticholinesterases for myasthenia gravis: synthesis and activities of quaternary phenylcarbamates of neostigmine, pyridostigmine and physostigmine. Bioorganic & Medicinal Chemistry 18:13, pages 4687-4693.
Crossref
Crossref
Francesca Mangialasche, Alina Solomon, Bengt Winblad, Patrizia Mecocci & Miia Kivipelto. (2010) Alzheimer's disease: clinical trials and drug development. The Lancet Neurology 9:7, pages 702-716.
Crossref
Crossref
Antoine Piau, F. Nourhashémi, C. Hein, C. Caillaud & B. Vellas. (2010) Progress in the development of new drugs in Alzheimer’s disease. The journal of nutrition, health & aging.
Crossref
Crossref
Roland Jakob-Roetne & Helmut Jacobsen. (2009) Alzheimer's Disease: From Pathology to Therapeutic Approaches. Angewandte Chemie International Edition 48:17, pages 3030-3059.
Crossref
Crossref
Roland Jakob-Roetne & Helmut Jacobsen. (2009) Die Alzheimer-Demenz: von der Pathologie zu therapeutischen Ansätzen. Angewandte Chemie 121:17, pages 3074-3105.
Crossref
Crossref
Manuela Bartolini, Nigel H. Greig, Qian-sheng Yu & Vincenza Andrisano. (2009) Immobilized butyrylcholinesterase in the characterization of new inhibitors that could ease Alzheimer?s disease. Journal of Chromatography A 1216:13, pages 2730-2738.
Crossref
Crossref
Donna M. Barten & Charles F. Albright. (2008) Therapeutic Strategies for Alzheimer’s Disease. Molecular Neurobiology 37:2-3, pages 171-186.
Crossref
Crossref