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Expert Opinion on Investigational Drugs Volume 20, 2011 - Issue 10
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Drug Evaluations

Vorapaxar: a novel protease-activated receptor-1 inhibitor

Paul A Gurbel Sinai Center for Thrombosis Research, 2401 W. Belvedere Ave, Baltimore, MD 21215, USA+1 410 601 9600; +1 410 601 9601; [email protected]
, MD,
Young-Hoon Jeong Sinai Center for Thrombosis Research, 2401 W. Belvedere Ave, Baltimore, MD 21215, USA+1 410 601 9600; +1 410 601 9601; [email protected]
, MD PhD &
Udaya S Tantry Sinai Center for Thrombosis Research, 2401 W. Belvedere Ave, Baltimore, MD 21215, USA+1 410 601 9600; +1 410 601 9601; [email protected]
, PhD
Pages 1445-1453 | Published online: 06 Aug 2011

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Amit Rout, Ajaypaul Sukhi, Rahul Chaudhary, Kevin P Bliden, Udaya S Tantry & Paul A Gurbel. (2020) Investigational drugs in phase II clinical trials for acute coronary syndromes. Expert Opinion on Investigational Drugs 29:1, pages 33-47.
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Udaya S. Tantry, Fang Liu, Gailing Chen & Paul A. Gurbel. (2015) Vorapaxar in the secondary prevention of atherothrombosis. Expert Review of Cardiovascular Therapy 13:12, pages 1293-1305.
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Articles from other publishers (14)

Rafika Yasmin, Shankar Chanchal, Mohammad Zahid Ashraf & Robin Doley. (2023) Daboxin P, a phospholipase A 2 of Indian Daboia russelii venom, modulates thrombin‐mediated platelet aggregation . Journal of Biochemical and Molecular Toxicology 37:11.
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Panagiotis Theofilis, Marios Sagris, Evangelos Oikonomou, Alexios S. Antonopoulos, Konstantinos Tsioufis & Dimitris Tousoulis. (2022) Factors Associated with Platelet Activation-Recent Pharmaceutical Approaches. International Journal of Molecular Sciences 23:6, pages 3301.
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Udaya S Tantry, Kevin P Bliden, Rahul Chaudhary, Marko Novakovic, Amit Rout & Paul A Gurbel. (2020) Vorapaxar in the treatment of cardiovascular diseases. Future Cardiology 16:5, pages 373-384.
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Gerasimos Siasos, Georgia Skotsimara, Evangelos Oikonomou, Marios Sagris, Mystakidi Vasiliki-Chara, Evanthia Bletsa, Panagiota Stampouloglou, Panagiotis Theofilis, Georgios Charalampous & Dimitris Tousoulis. (2020) Antithrombotic Treatment in Diabetes Mellitus: A Review of the Literature about Antiplatelet and Anticoagulation Strategies Used for Diabetic Patients in Primary and Secondary Prevention. Current Pharmaceutical Design 26:23, pages 2780-2788.
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Marie Lordkipanidzé & Paul Harrison. 2017. Platelets in Thrombotic and Non-Thrombotic Disorders. Platelets in Thrombotic and Non-Thrombotic Disorders 559 570 .
Marie Lordkipanidzé. (2015) Is platelet transfusion the solution to reverse platelet inhibition in patients on triple antiplatelet therapy?. Thrombosis Research 136:6, pages 1057-1058.
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Charles Feldman & Ronald Anderson. (2015) Community-Acquired Pneumonia. Chest 148:2, pages 523-532.
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Rahil Rafeedheen, Kevin P. Bliden, Fang Liu, Udaya S. Tantry & Paul A. Gurbel. (2015) Novel Antiplatelet Agents in Cardiovascular Medicine. Current Treatment Options in Cardiovascular Medicine 17:6.
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Lan Gao, Fei-Li Zhao & Shu-Chuen Li. (2015) Efficacy and Safety of Thrombin-Receptor Antagonist (Atopaxar and Vorapaxar) in Patients with Acute Coronary Syndrome or Coronary Artery Disease?A Meta-Analysis of Randomized Controlled Trials. Value in Health Regional Issues 6, pages 22-32.
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Paul A. GurbelAthan KuliopulosUdaya S. Tantry. (2015) G-Protein–Coupled Receptors Signaling Pathways in New Antiplatelet Drug Development. Arteriosclerosis, Thrombosis, and Vascular Biology 35:3, pages 500-512.
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Jung Hwa JungUdaya S. TantryPaul A. GurbelYoung-Hoon Jeong. (2015) Current Antiplatelet Treatment Strategy in Patients with Diabetes Mellitus. Diabetes & Metabolism Journal 39:2, pages 95.
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Raewyn M. Poole & Shelley Elkinson. (2014) Vorapaxar: First Global Approval. Drugs 74:10, pages 1153-1163.
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Kiran Kalra, Christopher J. Franzese, Martin G. Gesheff, Eli I. Lev, Shachi Pandya, Kevin P. Bliden, Udaya S. Tantry & Paul A. Gurbel. (2013) Pharmacology of Antiplatelet Agents. Current Atherosclerosis Reports 15:12.
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Karyn M. Austin, Nga Nguyen, Golrokh Javid, Lidija Covic & Athan Kuliopulos. (2013) Noncanonical Matrix Metalloprotease-1-Protease-activated Receptor-1 Signaling Triggers Vascular Smooth Muscle Cell Dedifferentiation and Arterial Stenosis. Journal of Biological Chemistry 288:32, pages 23105-23115.
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